The Histopathological Profile Of Kidney Diseases In A Single Center In Egypt: An Overview Of 14 Years Of Experience
Hamdy Ahmed Sliem, E-Mail: email@example.com
Background: The histopathological examination of biopsied kidneys is a gold standard for renal diagnosis. Currently, there is a lack of long-term data collection and studies on renal diseases, whether on glomerular or other forms. Therefore, the present study was designed to determine the histopathological profile of nephropathy in a single large center in Egypt in the last 14 years and to discuss the differences from other countries.
Methods: The study was a retrospective descriptive study. The demographical and clinical data were analyzed for all patients who underwent renal biopsy in the renal unit of the Suez Canal University Hospital. The records of the renal biopsies which were performed for them at the hospital from January 1996 until the end of December 2009 were retrospectively analyzed.
Results: The mean age of the patients was 27.19 Â± 14.31 years; 57.14 % were females and 42.86% were males. The most common indication of the kidney biopsy was nephrotic syndrome (43.1%), with the predominance of membranoproliferative glomerulonephritis (MPGN). The second indication was asymptomatic urinary abnormalities (AUA), (25.18%) and the third one was acute renal failure (15.98%). In all biopsies, MPGN was the most prevalent pathological diagnosis (38.74%), followed by membranous glomerulonephritis (22.76%). Lupus was the first co-morbid disease and the most frequent secondary glomerulonephritis.
Conclusion: Discussing the Egyptian registry for renal biopsy will help in increasing the understanding of the histopathology of renal diseases in Egypt in general and in the region of the Suez canal and Sinai in particular. Meticulous interest should be paid to AUAs, as about half of them had MPGN.