
A Histopathological study of Granulomatous Inflammations with an attemptto find the Aetiology
301-306
Correspondence
Dr Jayashree Pawale, C-14 staff quarters, SN Medical College
Bagalkot.587101. Karnataka.
Email address:jaishree_pawale@yahoo.co.in
ashutosh_pawale@yahoo.co.in, Phone: 09538161007
Granulomas are the commonest lesions that the pathologists come across in routine practice. In order to treat these lesions, definitive diagnosis by the demonstration of the aetiological agent is essential, which will bear an impact on the patient management and outcome.
Our aim was to find the aetiology in all the granulomatous lesions, on histopathologically evaluated biopsies.
A two year prospective study was done in KIMS; Hubli.The biopsies of the cases which were diagnosed as granulomas on H and E stained sections from all the sites were selected. Special stains like Ziehl-Neelsen stain, Gomori’s Methenamine silver, Fite Faraco and Auramine Rhodamine stain were done wherever required.
A total of 170 granulomatous lesions were studied. Granulomas with different aetiologies were seen. The commonest were the granulomas due to tuberculosis with 84 (49.41%) cases, followed by those with leprosy, rhinoscleroma, actinomycosis andfungal infections and foreign body granulomas and granulomas with unknown aetiology.
An attempt has to be made to put these granulomas into specific aetiological categories for specific treatment.
The morphology of the lesions and the use of special stains helped us to diagnose 159 out of the 170 cases.