Vitamin D and the Metabolic Syndrome in Indian Sub-population 89-91
Dr. Manuj Sharma
Department of Medicine,
Gandhi Medical College,
Bhopal, Madhya Pradesh.
Introduction:Low serum 5-hydroxyvitamin D [25(OH)D] levels have been related to insulin resistance, the metabolic syndrome (MetS) and its components. The aim of our analysis was to investigate the association of 25(OH)D with IDF-defined MetS.
Design: This was a cross-sectional study of 50 participants aged 15â€“65 years.
Results: Mean age of the participants was 42.14 years. 25(OH)D levels were inversely associated with BMI, waist circumference, systolic and diastolic blood pressure (BP), triglycerides, and fasting blood glucose (P<0.05). The percentage of subjects with MetS decreased across increasing quintiles of 25(OH)D (P<0.001).
Conclusions: Our results demonstrate an inverse relationship between 25(OH)D levels and MetS in the Indian sub-population studied. Further investigations are required to clarify the clinical significance of these findings.