Common Silent Liver Disease In and Around of Salem Population: An Autopsy Study 207-210
Dr. R. Thamil Selvi
Professor, Department of Pathology.
Vinayaka Missions Kirupananda Variyar Medical College and
Hospital, Salem, Tamilnadu, India.
Introduction: We aim to determine the prevalence of silent liver diseases and to correlate it with age, sex, life style and its other risk factors. Histopathology is an important and most useful way to find out the conditions of internal visceral organs and the unique method for diagnosis of liver diseases because the liver is the site of many diseases, of which become symptomatic while some are diagnosed only on autopsy. Histopathology study is conducted in 120 cases in VMKV. Medical College Hospital, in the department of Pathology Salem, Tamil Nadu, India.
Methods: The study was conducted over a period of two years (2009-2011) as elective and prospective study. We collected samples from 120 cases for histopathology study. Samples from the right and left lobe and one in the centre of the liver as well as other morphological findings was observed and recorded. Tissue sections were made and stained with Haematoxylin and eosin were evaluated.
Results: Of the 120 cases were studied, 12 cases were excluded due to autolysis. 108 cases have analysed for study, the cases ranging from 6 years to 80years. Among 108 cases, Males were 82 & Females were 26, with the mean age of 46+/-9.52 years. Fatty changes were found in 26.9% followed by normal 25.9%, congestion 16.7%, hepatitis 13.9%, cirrhosis & abscess 7.4% and malignancy 1.9%. Causes of death were RTA -51, poisoning-15, hanging-15, suspecious-11, myocardial infarction-5, drowning-4, burns and electrocution each 3 and 1 in railway.
Conclusion: From this study, the most common findings were fatty changes were more prone in the age of 50 â€“ 70 years and starts with 40 years of age due to chronic consumption of alcohol in the Population of Salem district, Tamil Nadu.