Acinetobacter spp.: An Emerging Pathogen in Neonatal Septicaemia 805-806
Dr.Jeyamurugan T., M.D. (Micro),
Assistant Professor Department of Microbiology,
Tirunelveli Medical College,
Tirunelveli District, 627 011, Tamil Nadu, India.
Background and objectives: Acinetobacter spp. are gaining importance as a potential pathogen in neonatal septicaemia because of its frequent isolation and multidrug resistance. The aim of the present study is to investigate the incidence of Acinetobacter septicaemia in neonates and its antibiotic resistance pattern.
Materials and Methods: Neonates admitted to the neonatal intensive care unit with signs suggestive of sepsis were recruited into this prospective study.Blood culture and Antibiotic sensitivity test were carried out.
Results: Out of 50, 14 were blood culture positive, Acinetobacter accounted for 5 (35.7%) of the blood culture positive sepsis. Other organisms were Citrobacter koseri(7.14%) Klebsiella oxytoca(7.14%), Staphylococcus aureus(14.29%), Klebsiella pneumoniae (21.42%), Pseudomonas aeruginosa (7.14%), Coagulase negative Staphylococci(7.14%).The organism was sensitive to Ampicillin (20%), Ciprofloxacin (40%), Amikacin (40%),Gentamicin(60),Doxycycline(20%),Cefotaxime(60%),Meropenem(100%),Imipenem(100%),Piperacillin+Tazobactam (100%).
Conclusions: Low birth weight and preterm delivery are the potential risk factors of Acinetobacter sepsis. Sensitivity of Acinetobacter has changed over the years, previously they are sensitive to cephalosporins but now they have become resistant to it.High incidence of sepsis in institutional delivery indicates that the theatre protocol should be maintained.28% of cases were only culture positive ,remaining clinical sepsis cases must be investigated for anaerobic infection.To prevent acinetobacter