A Rare Presentation of the Klinefelter’s Syndrome 1544-1546
Dr. Negar Sadat Taheri
Shahid Nabavi Polyclinics,
4th Azar Alley, 5 Azar Blvd, Gorgan, Iran.
Postal Code: 4917765181
Tel: +981712340835; Fax: +981712369210
A 16 years old boy with Chronic Renal Failure (CRF) was not suspected of having Klinefelterâ€™s syndrome until he complained of painful gynecomastia. He was under haemodialysis for 2 years. At first, he was in an approximately full pubertal development (P5, G5), but he had a small and a firm testis (length 2.2cm) and some degree of facial male pattern hair. He also had a decreased upper to lower body segment ratio and despite having chronic renal failure, he was taller than his parents and siblings. His laboratory tests showed high levels of FSH and normal levels of LH and testosterone. With regards to all these findings, we suspected that there might be an occult Klinefelterâ€™s syndrome. So, we made his karyotype that showed a 47XXY pattern. Because there are only a few number of cases that have occult Klinefelterâ€™s syndrome in the basis of chronic renal failure, we decided to report this case.