Systemic Sclerosis Presenting with Simultaneous Retinal Vasculitis in One Eye and Optic Neuritis in the other along with Severe Immune Haemolytic Anaemia 2978-2980
Dr. Avijit Moulick,
Flat 2F, Spandan Apartment. 1/14 Extn Chittaranjan Colony. Kolkataâ€“700032, West Bengal, India.
Phone: 9333656161, E-mail: firstname.lastname@example.org
Systemic Sclerosis (SSc) is a connective tissue disorder which involves multiple systems in a chronic progressive manner. Microâ€“angiopathic haemolytic anaemia is a distinguished feature of â€śscleroderma renal crisisâ€ť, which is manifested by severe hypertension, a rapidly progressing renal dysfunction and hyperreninaemia and is seen in patients with an early, diffuse form of the disease. A nervous system involvement is rare, though entrapment neuropathies have been reported. Who presented with a sequential loss of vision in both eyes; due to retinal vasculitis in right eye and optic nerve demyelination in the left eye. She also had severe Coombsâ€™ negative haemolytic anaemia in absence of any renal dysfunction or hypertension. Both the ophthalmologic and the haematologic manifestations are very rare and both responded well to oral prednisolone therapy.