A Case of Ankylosing Spondylitis and Discussion of the Literature
Dr. Ranjith M.P.
Bhavatharini, Pantheerankave P.O.
Kozhikode-673019, Kerala, India.
Ankylosing spondylitis (AS) is a systemic rheumatic disease.Its pathogenesis has not been completely understood, but the HLA-B 27 molecule, immune cells and cytokines are thought to be involved. Nonsteroidal anti-inflammatory agents are the first line of drugs and they effectively relieve the symptoms. Biological therapies which use Infliximab, which help in targeting the underlying inflammatory process in AS, have been used recently. Here, we are reporting a case of AS, with the established classical skeletal deformities.