Dentinogenesis Imperfecta: A Family which was Affected for Over Three Generations 1808-1811
Dr. Poornima Surendra,
Professor & HOD, Paediatric & Preventive Dentistry,College Of Dental Sciences, Davangere, Karnataka, India.
Phone: (+91)8105482841, E-mail: email@example.com
Dentinogenesis Imperfecta (DI) or hereditary opalescent dentin is inherited in a simple autosomal dominant mode with high penetrance and low mutation rates. It generally affects both the deciduous and the permanent dentitions. DI corresponds to a localized form of mesodermal dysplasia which is observed in the histo-differentiation. An early diagnosis and treatment are therefore fundamental, which aim at obtaining a favourable prognosis, since at late intervention makes the treatment more complex. We are presenting here a case of DI in which the disease affected the three generations of a family in India.