A Rare Case of Primary Supraclavicular Lymphadenitis due to Cryptococcus Neoformans in an HIV Infected Patient 137-138
Dr. Smriti Chauhan,
Medical Officer, Department of Microbiology, Dr Rajendra Prasad Government Medical College,
Kangra at Tanda, Himachal Pradesh, India.
Phone: +919418070808, E-mail: firstname.lastname@example.org
Cryptococcosis caused by encapsulated yeast Cryptococcus neoformans most commonly presents as disease of the central nervous system. Cryptococcus is a nonâ€“mycelial budding yeast found in soil, pigeon droppings and their nesting places. The three â€˜classicâ€™ virulence factors of cryptococci are: polysaccharide capsule, melanin production and growth at 37Â°C. Here, we present a rare case of cryptococcosis affecting left supraclavicular lymph node in a Human Immunodeficiency virus (HIV) infected individual. Culture of fine needle aspirate of the lymph node yielded Cryptococcus neoformans which was identified by standard microbiological techniques. Meyerâ€™s mucicarmine stain imparted a typical rose burgundy colour to the capsule. Unusual characteristics of the isolate included poorly developed capsule and the presence of yeast in chains resembling pseudo-hyphae. This case highlights the importance of microbiological techniques for diagnosis and prompt treatment of cryptococcosis.