Nasal Discharge Cytology an Important Diagnostic Method for Allergic Fungal Sinusitis: Report of Three Cases
Dr. Nalini Vinayak Kadgi,
B-403, Nancy Lake Homes, Opposite Bharati Vidyapeeth, Pune â€“ Satara Road, Katraj, Pune-411046, India.
Phone: 091- 9881690690, E-mail: firstname.lastname@example.org
Allergic fungal sinusitis (AFS) is a distinct clinicopathological entity. It occurs in immunocompetent individuals with history of atopy, increased IgE levels and peripheral eosinophilia and causes noninvasive pansinusitis. It is histologically characterised by the presence of â€˜allergic mucinâ€™ with clusters of eosinophils, charcot â€“ Leyden crystals and scattered fungal hyphae. AFS is an immunological reaction to fungal deposits. As AFS is noninvasive, fungal hyphae can be demonstrated in nasal secretions on cytology. Etiological agent of AFS is Aspergillus or pigmented dematiaceous family. Special stains are helpful for identification. We came across three cases of age group ranging from 26 to 60-year of recurrent rhinitis with nasal discharge. The nasal secretions were collected by nasal swabs onto the glass slide and stained with Giemsa and silver stains. Smears revealed fungal hyphae amidst inflammatory cells with occasional Charcot-Leyden crystals. Nasal secretion cytology plays an important role in diagnosis and can be used for preoperative as well as intraoperative diagnosis of AFS and can be used as an additional diagnostic tool.