Multicentric Metaplastic Breast Carcinoma with Squamous Differentiation ED09-ED10
Dr. Sunil V Jagtap,
Professor, Department of Pathology, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India.
Metaplastic breast carcinoma is a rare primary breast malignancy. A 45-year-old female patient presented with multicentric lumps in left breast of 6 months duration and history of axillary lymphadenopathy of 2 months duration. Mammography revealed two high density masses with ill defined margins. Fine needle aspiration cytology was positive for duct carcinoma cells. Histo pathologic examination, reported as â€śMulticentric infiltrating duct carcinoma with squamous differentiation left breastâ€ť, grade 2. Immunohistochemistry revealed negativity for ER, PR and positivity for HER-2neu. We are presenting this rare case for clinical, radiological, histopathological and immunohistochemical study.