Mastication Frequency and Postprandial Blood Sugar Levels in Normoglycaemic and Dysglycaemic Individuals: A Cross- Sectional Comparative study OC06-OC08
Dr. Arun Shirali,
Associate Professor, Department of Internal Medicine, KMC â€“ Attavar, Manipal University, Mangalore, India.
Introduction: Mastication has potential to affect postprandial blood glucose levels by affecting cephalic phase of insulin release. However, limited number of studies done in this regard has yielded conflicting results.
Aim: To evaluate effects of mastication on postprandial blood glucose levels.
Materials and Methods: We compared routine and thorough mastication in 2 separate groups: dysglycaemic (prediabetics and diabetics) and normoglycaemic in prospective interventional study. Blood glucose levels were measured pre-prandial and postprandial (after 2 hours) on separate days after routine and thorough mastication in both groups.
Results: In normoglycaemic group, thorough mastication significantly reduced postprandial blood glucose levels at 2 hours (128.25Â± 7.82 mg/dl on routine mastication vs 119.74Â±9.08 mg/dl on thorough mastication, p<0.05). Comparatively, in dysglycaemic group, thorough mastication had little effect on postprandial blood glucose levels at 2 hours (244.07Â±22.37 mg/dl vs. 243.55Â±22.87 mg/dl).
Conclusion: In normoglycaemic group, postprandial blood glucose concentration upon thorough mastication was significantly lower, due to early-phase insulin secretion. This simple lifestyle modification of thorough mastication can be a useful preventive measure against diabetes in people with a strong family history and other risk factors for diabetes who have not yet developed diabetes or prediabetes.