Histopathological Study of Incidental or Opportunistic Salpingectomy Specimens and the Association of Tubal and Ovarian Lesions in South Eastern Nigeria EC13-EC17
Dr. Nnaemeka Thaddeus Onyishi,
Consultant Pathologist, Department of Histopathology, Enugu State University College of Medicine, Parklane Enugu, Nigeria.
Introduction: There is heightened interest on the fallopian tube in recent times. Most reports on the subject emanate from western countries thus data on fallopian tube is lacking in Nigerian and African populations.
Aim: To establish the histopathological status of grossly normal fallopian tube specimens and the pattern of gynaecological disease contributing to concomitant resection of normal fallopian tube and to determine if there are any association between tubal and uterine and or ovarian lesions.
Materials and Methods: The study was a prospective cross-sectional study of incidental fallopian tubes received at University of Nigeria Teaching Hospital and Enugu State University Teaching Hospital from 1st January 2012 to 31st December 2014. The Haematoxylin and Eosin (H&E) stained sections of the entire tube were examined. Statistical analysis was done using IBM SPSS software version 20.0. Measures of central tendency and variation were calculated for numerical variables while frequency and proportions were calculated for categorical variables. Fisher’s-Exact and chi-square tests were done as appropriate.
Results: Fallopian tubes from 120 female subjects were studied. The mean age of the women was 48.7±10.1 (range: 26-79) years. Sixty one out of the 120 women (61/120, 50.8%) had fallopian tubes within normal limits. Eighty lesions were identified in fallopian tubes of 49.2% (59/120) of the women. No case of Serous Tubal Intraepithelial Carcinoma (STIC) was diagnosed. Statistically significant association was seen between ovarian sex cord stromal tumours and moderate to marked epithelial hyperplasia of the fallopian tube (p<0.001).
Conclusion: Extensive sampling protocol revealed identifiable pathological, mostly benign lesions in 49.2% of grossly normal fallopian tubes. Diseases of the uterine corpus, particularly uterine leiomyoma, were the commonest cause of incidental fallopian tube resection.