Acute Disseminated Encephalomyelitis: A Rare Complication of Varicella Zoster Infection in an Adult OD01-OD03
Dr. S Anuradha,
Director Professor, Department of Medicine, Maulana Azad Medical College, Bahadur Shah Zafar Marg, New Delhi-110002, India.
Acute Disseminated Encephalomyelitis (ADEM) is a mutifocal, demyelinating disease of the brain and spinal cord of acute onset. It usually occurs after viral infections or post vaccination. Its occurrence in immunocompetent middle-aged adults, that too without cerebral dysfunction following Varicella Zoster Virus (VZV) infection is extremely rare. Here, we report a case of a 42-year-old female who developed ADEM after an episode of VZV infection. The patient responded dramatically to corticosteroids and made complete neurological recovery. Though she had extensive lesions on her brain MRI, she had no symptoms/signs related to brain involvement clinically. To the best of our knowledge, such a presentation has not been reported in literature so far.