Osteoclasts: Multifaceted Molecule in Vesicular Trafficking ZE01-ZE05
Dr. Jaideep Mahendra,
Department of Periodontics, Faculty of Dentistry, Meenakshi Academy of Higher Education and Research, No. 1,
Alapakkam Main Road, Maduravoyal, Chennai-600095, Tamil Nadu, India.
It has been widely accepted that periodontitis is a result of the host immune inflammatory response caused by various periodontal microorganisms leading to tissue degradation and bone resorption. One important mechanism of the inflammatory mediators present in periodontal tissue is the stimulation and formation of osteoclasts that are believed to be the major cell type responsible for bone resorption. This review article comprehensively explains the various molecular activities of osteoclasts and their role in periodontitis.