A One-Year Treatment Outcome Comparison of Pulpotomies in Primary Molars using Biodentine and Formocresol in Thai Children: A Randomised Control Trial ZC17-ZC21
Department of Paediatric Dentistry, Faculty of Dentistry, Mahidol University,
6 Yothee Street, Ratchathewi, Bangkok-10400.
Introduction: Pulpotomy is the treatment to preserve radicular pulp in order to maintain the integrity of the teeth after caries or traumatic exposure. Pulpotomy medication has been studied for many years. Biodentine is a new material which has been studied recently and showed promising results.
Aim: To evaluate the clinical and radiographic outcomes and compare the treatment success rate in primary molars using biodentine and formocresol during a 12 months period.
Materials and Methods: A parallel-design, randomised control trial was performed in children aged 3 to 8 years old who had at least one primary molar that required pulpotomy treatment. Fifty teeth were selected from 38 children and randomly assigned into two groups which were formocresol (n=25) and biodentine (n=25) as pulpotomy agents. The final restoration for all teeth were stainless steel crown. Clinical and radiographic outcomes were evaluated at 6 and 12 months after the treatment. Chi-square test was used for statistical analysis between two groups (significance level at p<0.05).
Results: A total of 50 primary molars were included in this study. Both groups were the same in terms of age, sex and tooth treated. At 6 months, 47 teeth were available to follow-up (23 from formocresol, 24 from biodentine). At 12 months, 45 teeth were available to follow-up (23 from formocresol, 22 from biodentine). An additional two teeth from biodentine group were lost due to patient relocation. Clinical success rates for both groups were 100% at 6 and 12 months follow-up. The radiographic success rate at 6 month follow-up in formocresol and biodentine groups were 65% and 79%, respectively. The radiographic success rate at 12 month follow-up in formocresol and biodentine groups were 74% and 96%, respectively. There was statistically difference in radiographic success rates between 2 groups at 12 months follow-up (p=0.022).
Conclusion: Biodentine showed similar clinical effective and higher radiographic success rate at 12 months follow-up when compared to formocresol. Biodentine can be used as pulpotomy medicaments alternative to formocresol in primary teeth.