A Comparative Study of Serum Uric Acid and Serum Magnesium Level in Diagnosed Cases of Various Renal Disorders
Dr. Arup Jyoti Baruah,
Associate Professor, Department of General Surgery, Room No. 25, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Ma Wdiangdiang, East Khasihills, Shillong-793012, Meghalaya, India.
Introduction: Estimation of serum uric acid and magnesium along with other sensitive markers of renal function (serum creatinine and urea) are very effective to determine extent of renal impairment.
Aim: To compare the serum uric acid and magnesium level between controls and patients with various renal diseases and also to evaluate any correlation of these two parameters with severity of impairment (creatinine and urea).
Materials and Methods: Serum uric acid and magnesium estimation in 20 controls and 50 cases (28 males and 22 females; age 14-64 years) with various renal diseases (five cases of acute glomerulonephritis, 10 cases of acute renal failure, eight cases of acute pyelonephritis and 27 cases of chronic renal failure) were done during a period of one year in North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Shillong, India.
Results: The serum magnesium and uric acid in control group were found within normal range with no significant variations observed in different age and sex. Both the parameters were found to be raised above their standard normal value in all 50 cases and also the parameters in the study showed positive correlation with serum creatinine and urea, so result of this study was significant (p-value <0.001).
Conclusion: Estimation of serum uric acid and magnesium are sensitive for the establishment of diagnostic and prognostic aspect in various renal diseases.