Prognostic Factors on Survival of Rasoul-e-Akram Hospital Patients with Colorectal Cancer: A Survival Analysis
Dr. Mojtaba Soltani-Kermanshahi,
Department of Epidemiology and Biostatistics, Semnan University of Medical Sciences, Semnan, Iran.
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Introduction: Colorectal Cancer (CRC) also called colon cancer or intestine cancer is characterised by cancerous growth of cells in the rectum, colon and appendix. CRC is the fourth most common form of cancer after skin, gastric, bladder and prostate cancers among Iranian population, since 6-8 people per 10,000 people suffer from this disease.
Aim: To evaluate the prognostic factors on survival of patients with CRC, in Rasool-e-Akram Hospital in Tehran, Iran.
Materials and Methods: The population under study included patients with CRC, admitted between 30 March 2010 to 29 March 2013, in Rasoul-e-Akram teaching hospital affiliated with Iran University of Medical Sciences, Tehran, Iran. The event was death from CRC and any other cause. Possible prognostic variables were selected from documents. A multivariate Cox regression model was performed to study the concurrent effect of parameters on survival after taking into account the parallel effect of residual factors.
Results: In this research 80 patients were studied. With respect to inclusion and exclusion criteria 68 patients were enrolled and data related to 68 patients were exposed to statistical analysis. Median and mean age of patients were equal to 55.5 and 55.0 years, respectively with standard deviation of 13.9 years. Only â€śLogarithm of White Blood Cellâ€ť showed a significant effect on survival of patients with CRC.
Conclusion: The results of our study showed the effect of WBC on survival of patients with CRC. Accordingly the increased one unit of log WBC increased the death hazard by 21.22 times in CRC patient.