Exophiala jeanselmei and Rhizopus oryzae Co-infection Post Renal Transplant
Dr. Immaculata Xess,
Professor, Department of Microbiology, AIIMS, Delhi, India.
Invasive fungal infections are associated with morbidity and mortality in immunocompromised patients. Dematiaceous fungi are being increasingly recognised as human pathogens, particularly in transplant recipients. However, most cases of dematiaceous fungal infections after organ transplantation have been reported as sole aetiological agents. We report a case of fatal, disseminated phaeohyphomycosis with rhinocerebral mucormycosis in post renal transplant patient. Quick diagnosis is challenging and inspite of aggressive management with a combination of surgical and medical therapies, the outcome is poor. Amphotericin B remains the cornerstone in the medical management of mucormycosis and itraconazole in phaeohyphomycosis, still we are short of drugs to fight against such catastrophic organisms.