A Case of Macrophagic Activation Syndrome in a Child with Epilepsy Treated with an Excessive Dose of Sodium Valproate ED04-ED05
Dr. Kambourou Judicael,
Lecturer, Department of Paediatrics, Faculty of Health Sciences, University Marien NGOUABI, Brazzaville, Congo.
Macrophagic Activation Syndrome (MAS) is a rare disorder and is thought to result from non-malignant activation and proliferation of macrophages and T-cells. It can be of primary or secondary origin and its prognosis is often poor. We report a case of a three-year-old boy admitted in the intensive care unit for MAS secondary to an overdose of sodium valproate to remind practitioners to think about it in the presence of a febrile pancytopenia.