Minoxidil a Youth Elixir for Eyebrow Hypotrichosis PC01-PC03
Dr. Yeshwant Lamture,
J.N.M.C., Wardha-442005, Maharashtra, India.
Introduction: Eyebrows being prominent feature of the face contributes majorily for aesthetics. Eyebrow hypotrichosis means the reduction or absence of the eyebrow hair. This is associated with negative self-esteem. Minoxidil has been found to act at the level of hair follicle by direct stimulation of follicular epithelial growth, increase cutaneous blood flow, and stimulate resting hair follicles.
Aim: To study the potential role of Minoxidil for the treatment of eyebrow hypotrichosis.
Materials and Methods: It was a prospective interventional study comprising of 22 subjects aged 18 years or more having eyebrow hypotrichosis. These patients garded as Grade 1 or 2 hairloss on the Allergan Global Eyebrow Assessment (GEBA) scale. All the patients were advised to apply 1 mL of 2% minoxidil lotion to eyebrow twice a day for four months. Comparison of the change in global photographic score (Subjectâ€™s satisfaction) before and after Minoxidil treatment was done, also comparison of the diameter and number of eyebrow hairs/cm2 areas between pre and post-treatment done. Paired t-test was used to compare diameter and number of eyebrow before and at the end of treatment.
Results: Before treatment with Minoxidil the average hair shaft diameter was 0.034±0.0057 mm and density was 17±5.03 hairs/ cm2 . After treatment this improved to 0.07±0.0045 mm and 30Â±7.03 hairs/cm2 , respectively. The global photographic score was -2.1±0.76 before treatment that increased to -1.3±0.89 at four weeks and reached a peak of 2.3±0.55 at 16 weeks. The incidence of adverse events was 22.72% (5/22 subjects) which included mild itching and burning.
Conclusion: This study showed that 2% Minoxidil is a welltolerated and effective treatment for eyebrow hypotrichosis.