Abrikossoff’s Tumour of Oesophagus- An Innocent Bystander or a Silent Killer? OD01-OD02
Dr. Kuppusamy Senthamizhselvan,
Department of Medical Gastroenterology, Superspeciality Building, JIPMER, Dhanvantari Nagar, Puducherry, India.
Oesophageal Granular Cell Tumour (GCT) is a rare tumour arising from Schwann cells of the sub-mucosal nerve plexus. They are slow growing, generally benign though malignant potential has been reported. They are usually found incidentally during endoscopic evaluation of dyspepsia or dysphagia. They rarely produce symptoms on their own unless the size is larger, ulceration occur on their surface or when it compresses the adjacent structure. Though they are sub-mucosal, they are usually diagnosed by standard biopsy techniques or after an endoscopic resection. Oesophageal GCTs without muscularis propria attachment are amenable for Endoscopic Sub-mucosal Dissection (ESD) which is a minimally invasive procedure when compared to surgical resection. They may require follow-up after resection. Here, we report a case of 39-year-old male, who presented with epigastric pain and heart burn and underwent endoscopy for the same, which revealed a sub-centimetric, yellowish white flat lesion above oesophago-gastric junction. Biopsy was done and histopathology and immuno-histochemistry revealed sheets of tumour cells with clear granular cytoplasm, which stained positive for S100 and Calretinin, with a Ki-67 index of 2%, confirming the diagnosis of a benign GCT. Endoscopic Ultrasound (EUS) revealed no local invasion and the patient was advised three months follow-up and annual surveillance endoscopy.