Development and Validation of Persian Risk Assessment Tool using National Comprehensive Cancer Network Guideline for Colorectal Cancer Screening LC01-LC05
Mohammad Hossein Somi,
Liver and Gastrointestinal Diseases Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran.
Introduction: Despite evidence that early diagnosis of Colorectal Cancer (CRC) reduces the associated death burden, screening programs are uncommon even in developed countries.
Aim:To develop and validate a simple, practical and efficient tool to improve CRC risk assessment by identifying moderate- and high-risk disease.
Materials and Methods: The National Comprehensive Cancer Network guideline has been used to develop the CRC risk assessment tool. Content validity was assessed by a panel of 10 experts by generating a Content Validity Index (CVI), which was recorded quantitatively as the proportion of experts who agreed that the item was relevant, before calculating the Content Validity Ratio (CVR) per item.
Results: The CVI was in the range 0.7-1 and the acceptable CVR was in the range 0.4-1. The overall mean CVI and CVR values were 0.93 and 0.62, respectively. Changes were made according to the expertsâ€™ recommendations, and the final online Persian questionnaire was assessed for face validity by 15 individuals (general population voluntarily). Only a few items subsequently needed modification and expansion.
Conclusion: The Persian Risk Assessment tool is simple, quick, and easy to apply to different clinical categories and subcategories of CRC and can even be self-administered. This is the first translated tool in Persian version, usable in Iran.