Sleep Quality and Cognitive Dysfunction among Acute Stroke Patients from Coastal Areas of North Sulawesi, Indonesia OC06-OC09
Sekplin AS Sekeon,
FKM Unsrat, Kompleks Kampus Unsrat Kleak Manado, 95115, Manado, North Sulawesi, Indonesia.
Introduction: Poor sleep quality is one of the non conventional risk factors for stroke. Cognitive dysfunction is prevalent among stroke survivors. There is limited data on the association between sleep quality and cognitive dysfunction among stroke patients from coastal areas of Indonesia.
Aim: The objective of this study was to analyse the association between sleep quality and cognitive dysfunction among acute stroke patients from coastal areas in North Sulawesi province.
Materials and Methods: This was a hospital-based cross-sectional study. Samples of 78 acute stroke patients from coastal areas were consecutively selected. The dependent variable was cognitive dysfunction measured by Mini Mental Status Examination (MMSE). The independent variable was pre stroke sleep quality measured by the Pittsburgh Sleep Quality Index (PSQI). Stroke was diagnosed from history taking, physical examination, and/or neuroimaging study. The data were analysed by Chi-square test and Odds Ratio.
Results: More than half of 78 (52.6%) patients were female, with the mean age 59.71 (SD=13.78), and majority in 51-60 years age group (30.8%). Patients mostly graduated from high school (48.7%), lived in urban area (60.3%) and suffered ischemic stroke (62.8%). Poor sleep quality was found in 79.5% patients and cognitive dysfunction was detected in 53.9% patients. Stroke patients with poor sleep quality were almost two times more likely to experience cognitive dysfunction than counterparts with good quality of sleep (OR=1.89; 95%CI=0.54 to 6.55; p=0.467). The association between sleep quality and cognitive dysfunction among acute stroke patient from coastal areas of North Sulawesi province of Indonesia was not statistically significant.
Conclusion: Although poor sleep quality had a likely higher risk to develop cognitive disorders among acute stroke, but we could not establish significant association between sleep quality prior to stroke attack with impairment of cognitive function.