An Analysis of Treatment and Prognosis of Spinal Tuberculosis: A Prospective Study done in Tertiary Care Centre RC11-RC13
Dr. Varun Singh,
Department of Orthopaedics, Saraswathi Institute of Medical Science, NH-24,
Anwarpur, Pilakhuwa, Hapur-245304, Uttar Pradesh, India.
Introduction: In cases of skeletal Tuberculosis (TB), spinal TB is considered to be the most hazardous. Early treatment of spinal TB brings somewhat fine projections as well.
Aim: To evaluate the treatment and prognosis of patients with spinal TB.
Materials and Methods: The study involved patients with spinal TB from the period of 2017 to 2019. The total of 67 patients were included and follow-ups were made during the entire period of healing. Patients diagnosed with spinal TB and had not previously received anti-TB therapy and debridement or radical decompression surgery were included. A paired t-test was used to compare the pre-treatment and post-treatment clinical data. A p-value <0.05 was considered statistically significant.
Results: The male patients comprised of the 62.7% of the total sample size. At the final follow-up, the Visual Analogue Scale (VAS) score significantly improved from 5.99±2.11 preoperatively to 1.90±4.81 postoperatively (0<0.05), the Cobb angle significantly decreased from 16.84±6.42 preoperatively to 3.86±2.26 postoperatively (0<0.05). The Erythrocyte Sedimentation Rate (ESR) significantly decreased from 45.26±12.26 preoperatively to 9.91±6.48 postoperatively (0<0.05), and C-Reactive Protein (CRP) also significantly decreased from 49.22±42.31 to 9.84±11.53.
Conclusion: Quick treatment and diagnosis of spinal TB are essential to prevent permanent neurological disability and to minimise spinal deformity.