A black intruder into the Pandemic: Rhino-Orbital Mucormycosis Complicating COVID-19 NR01-NR04
Dr. Keya Chakrabarti,
Gymkhana Palm Heights, B804, Bharatpur, Bhubaneshwar, Odisha, India.
There is an increased incidence of rhino orbital mucormycosis during the Coronavirus Disease-2019 (COVID-19) pandemic attributed to Diabetes Mellitus, corticosteroid usage and immunocompromise caused by COVID-19. In this series, seven biopsy-proven cases of mucormycosis (six male patients and 1 female patients) are presented from a tertiary center in eastern India from (May 2021 to June 2021). Empirical systemic liposomal amphotericin B, radical sinus surgery with orbital decompression and irrigation of sinus and orbit with amphotericin B was performed. The mean age of the patients was 42.71±7.34 years with a male preponderance (85.7%). Five patients had orbital involvement (71.42%), and two had cerebral involvement (28.6%). All of them had elevated blood glucose levels, though only three (42.85%) were known cases of type 2 diabetes. The most common manifestations were sinus tenderness (100%), paresthesia (100%), facial swelling (71.42%) and nasal discharge (28.57%). Follow-up at two months showed zero mortality. Timely diagnosis, appropriate management with intravenous amphotericin B and endoscopic radical sinus surgery, debridement of the necrotic tissue proved to be necessary for a good outcome in rhino-orbito-cerebral mucormycosis.