Haemorrhagic Retinopathy Associated with Zieve Syndrome
Dr. Abdul Waris,
Assistant Professor, Department of Ophthalmology, Aligarh Muslim University,
Institute of Ophthalmology, Jawaharlal Nehru Medical College and Hospital,
Aligarh-202002, Uttar Pradesh, India.
Zieve syndrome, a rarely reported case is a triad of jaundice, haemolytic anaemia and hyperlipidaemia that develops secondary to alcohol-induced liver injury. Here in, a case of a 23-year-old young male with history of steatohepatitis is reported who presented with diminution of vision in both eyes. On fundoscopy, there were extensive retinal haemorrhages involving fovea. Workup was consistent with haemolytic anaemia with no source of active bleeding. The patient was managed with supportive treatment. No specific ocular treatment was given. However, the vision gradually improved during follow-up. A rare association of Zieve syndrome with haemorrhagic retinopathy is described here. Moreover, Zieve syndrome has been described in the literature, mostly in nonEnglish language case studies and is still under-recognised and under-reported. Diagnosis should be made quickly to avoid unnecessary invasive diagnostic interventions.