Early Onset Sarcoidosis/Blau Syndrome: Disguising as Juvenile Idiopathic Arthritis
Dr. Seema Singh,
Assistant Professor, Department of Pathology, Rajasthan University of Health Sciences, Jaipur, Rajasthan, India.
Blau Syndrome (BS) is a rare autoinflammatory granulomatous disorder which mostly develops at an early age (less than four years) and is described by granulomatous dermatitis, symmetric arthritis and recurrent uveitis. Hereby, the authors present a case of a 5-year-old female child with joint pain and swelling since four years. Initially, her diagnosis was made as juvenile idiopathic arthritis-polyarticular Rheumatoid Factor (RF) negative and was initiated on methotrexate along with bridge steroids (prednisolone). When she presented to the hospital, she had skin coloured micropapular rashes, mostly non follicular over body, from last nine months and after skin and synovial biopsy, the diagnosis was reviewed as early onset sarcoidosis/BS-sporadic type. The present rare report highlights that, BS is an under-recognised and reported childhood arthritis which may have multisystem involvement. The onset of arthritis without ocular or skin manifestations may be mistaken as juvenile idiopathic arthritis.