Effect of Air versus 1% Lignocaine used for Endotracheal Tube Cuff Inflation on Laryngotracheal Morbidity after Laparoscopic Surgery- A Randomised Clinical Study
Dr. Nirali Nimeshkumar Panchal,
8, Shaligram Greens, Rambhai Kaka Marg, Bakrol, Anand, Gujarat, India.
Introduction: Endotracheal intubation in general anaesthesia is associated with post intubation morbidity due to prolonged inflation of Endotracheal Tube (ETT) cuff with air. During laparoscopic surgery their incidence increases further. Lignocaine is likely to diffuse through ETT cuff when instilled into it. As a result, it decreases coughing, sore throat and hoarseness by reducing local irritation and inflammation of the airway.
Aim: To compare the effect of air and 1% lignocaine used for ETT cuff inflation on postoperative sore throat, hoarseness of voice and coughing in patients undergoing laparoscopic surgeries.
Materials and Methods: This double-blind randomised clinical study was conducted at Shree Krishna Hospital, Karamsad, Gujarat, India, between September 2021 to March 2022. Total of 54 patients were randomly divided into two groups with 27 in each; group A (air) and group X (1% lignocaine= 2% lignocaine and equal volume of normal saline). Postextubation patients were assessed for Postoperative Sore Throat (POST), hoarseness and coughing at 2 hours and 18-24 hours. Fisher’s Exact test was used to find the association between categorical variables in both the groups. The p<0.05 was considered statistically significant.
Results: The mean age in group A was 46.04±10.26 years, and in group X was 48.59±10.92 years. At 2 hours, in group X 11% (n=3) of patients had POST as compared to group A where nine patients (33%) reported POST (p=0.099). Group X showed a significantly reduced incidence of POST at 18-24 hours, hoarseness of voice, coughing at 2 hours and at 18-24 hours as compared to group A.
Conclusion: The use of 1% lignocaine for ETT cuff inflation in laparoscopic surgeries was associated with reduced incidence of POST, hoarseness of voice and coughing as compared to air.