Varied Histomorphological Presentations of Appendiceal Neoplasms: A Case Series of Eight Cases
ER10-ER14
Correspondence
Dhivya Balaiya,
Assistant Professor, Department of Pathology, Thanjavur Medical College, Thanjavur-613004, Tamil Nadu, India.
E-mail: dhivyasmc05@gmail.com
During routine histopathological study of appendicular specimens, we identified eight cases of appendiceal tumours, including five cases of Low-grade Appendiceal Mucinous Neoplasms (LAMN) and three cases of adenocarcinoma. Among the adenocarcinoma cases, one was a rare colorectal type adenocarcinoma in an older male and two were mucinous adenocarcinoma which includes a case of signet ring cell rich type. These tumours were classified and staged according to the recent WHO classification (5th edition) and the eighth edition of the American Joint Committee of Cancer (AJCC) staging manual. The median age in our series was 60 years. Serum markers were evaluated in two cases of Pseudomyxoma Peritonei (PMP), which showed elevated levels of CA-125 and CA 19.9 in each case. In this case series, three patients were initially diagnosed with acute appendicitis, one case as mucocele, two cases underwent surgery for ovarian malignancy, one patient was operated for an incisional hernia, and one patient was diagnosed with acute intestinal obstruction after clinical and radiological investigations. Histopathological examination confirmed the diagnosis of appendicular neoplasms in these eight cases. Meticulous histopathological examination of all appendectomy specimens is important for the proper diagnosis of appendicular neoplasms and to predict their severity. This will help surgeons plan further treatment to increase the patient’s survival rate.