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Intersection of Coeliac Disease and Sjogren’s Syndrome: A Report of Two Cases
Correspondence Address :
Dr. Ravi Talapa,
Postgraduate Student, Department of Medicine, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, New Delhi-110001, India.
E-mail: rtblaze1998@gmail.com
Coeliac Disease (CD) and Sjogren’s Syndrome (SS), both autoimmune disorders, are gaining attention for their complex interaction when occurring together. CD involves gluten intolerance and can present with gastrointestinal symptoms, while SS affects various organs, primarily causing dryness of the eyes and mouth. Diagnosis for each relies on specific criteria including serologic testing and histopathology. When these conditions overlap, they create unique clinical challenges, highlighting the need for a thorough understanding of their combined effects on health. This exploration aimed to uncover the intricacies of their relationship, including clinical manifestations and implications for diagnosis and management when dealing with both simultaneously. In both cases (58-year-old female and 47-year-old female), there was gastrointestinal villous atrophy as a manifestation of CD, which improved with simple dietary modification.
Anti-tissue transglutaminase, Autoantibodies, Immunoglobulin A, Villous atrophy
DOI: 10.7860/JCDR/2024/69885.19469
Date of Submission: Feb 01, 2024
Date of Peer Review: Mar 05, 2024
Date of Acceptance: Apr 08, 2024
Date of Publishing: Jun 01, 2024
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Feb 02, 2024
• Manual Googling: Mar 12, 2024
• iThenticate Software: Apr 06, 2024 (10%)
ETYMOLOGY: Author Origin
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