Subcutaneous Panniculitis-Like T-Cell Lymphoma: A Rare Tumour
Correspondence Address :
Dr. Pradeep Kumar Reddy Kistampally,
Junior Resident, Department of Medical Oncology, Kasturba Medical College & Hospital, Manipal, Karnataka, India.
E-mail: kpkreddy.kmc@gmail.com
Subcutaneous Panniculitis like T cell Lymphoma (SPTCL) is an uncommon variant and poorly differentiated type of cutaneous T cell lymphoma. Here we describe the case of a 19-year-old female who presented with swelling of left half of the face with no regional lymphadenopathy and hepatosplenomegaly which was initially misdiagnosed as a benign cutaneous condition by various practitioners. Histopathological examination revealed diffuse infiltration of subcutaneous plane by small to medium sized atypical lymphocytes. Immunohistochemistry showed CD3, CD8 and ßF-1 positivity; CD20, CD56, Epstein Barr Virus (EBV) and TCR-d negativity. Clinical profile, histopathology and immunohistochemical analysis yielded a diagnosis of SPTCL. Thus cases with atypical and nonresolving dermatological lesions should raise a suspicion of SPTCL as diagnosis against other benign conditions.
Atypical lymphocytes, Cutaneous condition, Face, Non resolving
DOI: 10.7860/JCDR/2016/18458.7824
Date of Submission: Dec 22, 2015
Date of Peer Review: Mar 15, 2016
Date of Acceptance: Mar 26, 2016
Date of Publishing: May 01, 2016
Financial OR OTHER COMPETING INTERESTS: None.
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