Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

Users Online : 95328

AbstractCase ReportDiscussionReferences
Article in PDF How to Cite Citation Manager Readers' Comments (0) Audio Visual Article Statistics Link to PUBMED Print this Article Send to a Friend
Advertisers Access Statistics Resources

Dr Mohan Z Mani

"Thank you very much for having published my article in record time.I would like to compliment you and your entire staff for your promptness, courtesy, and willingness to be customer friendly, which is quite unusual.I was given your reference by a colleague in pathology,and was able to directly phone your editorial office for clarifications.I would particularly like to thank the publication managers and the Assistant Editor who were following up my article. I would also like to thank you for adjusting the money I paid initially into payment for my modified article,and refunding the balance.
I wish all success to your journal and look forward to sending you any suitable similar article in future"

Dr Mohan Z Mani,
Professor & Head,
Department of Dermatolgy,
Believers Church Medical College,
Thiruvalla, Kerala
On Sep 2018

Prof. Somashekhar Nimbalkar

"Over the last few years, we have published our research regularly in Journal of Clinical and Diagnostic Research. Having published in more than 20 high impact journals over the last five years including several high impact ones and reviewing articles for even more journals across my fields of interest, we value our published work in JCDR for their high standards in publishing scientific articles. The ease of submission, the rapid reviews in under a month, the high quality of their reviewers and keen attention to the final process of proofs and publication, ensure that there are no mistakes in the final article. We have been asked clarifications on several occasions and have been happy to provide them and it exemplifies the commitment to quality of the team at JCDR."

Prof. Somashekhar Nimbalkar
Head, Department of Pediatrics, Pramukhswami Medical College, Karamsad
Chairman, Research Group, Charutar Arogya Mandal, Karamsad
National Joint Coordinator - Advanced IAP NNF NRP Program
Ex-Member, Governing Body, National Neonatology Forum, New Delhi
Ex-President - National Neonatology Forum Gujarat State Chapter
Department of Pediatrics, Pramukhswami Medical College, Karamsad, Anand, Gujarat.
On Sep 2018

Dr. Kalyani R

"Journal of Clinical and Diagnostic Research is at present a well-known Indian originated scientific journal which started with a humble beginning. I have been associated with this journal since many years. I appreciate the Editor, Dr. Hemant Jain, for his constant effort in bringing up this journal to the present status right from the scratch. The journal is multidisciplinary. It encourages in publishing the scientific articles from postgraduates and also the beginners who start their career. At the same time the journal also caters for the high quality articles from specialty and super-specialty researchers. Hence it provides a platform for the scientist and researchers to publish. The other aspect of it is, the readers get the information regarding the most recent developments in science which can be used for teaching, research, treating patients and to some extent take preventive measures against certain diseases. The journal is contributing immensely to the society at national and international level."

Dr Kalyani R
Professor and Head
Department of Pathology
Sri Devaraj Urs Medical College
Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka
On Sep 2018

Dr. Saumya Navit

"As a peer-reviewed journal, the Journal of Clinical and Diagnostic Research provides an opportunity to researchers, scientists and budding professionals to explore the developments in the field of medicine and dentistry and their varied specialities, thus extending our view on biological diversities of living species in relation to medicine.
‘Knowledge is treasure of a wise man.’ The free access of this journal provides an immense scope of learning for the both the old and the young in field of medicine and dentistry as well. The multidisciplinary nature of the journal makes it a better platform to absorb all that is being researched and developed. The publication process is systematic and professional. Online submission, publication and peer reviewing makes it a user-friendly journal.
As an experienced dentist and an academician, I proudly recommend this journal to the dental fraternity as a good quality open access platform for rapid communication of their cutting-edge research progress and discovery.
I wish JCDR a great success and I hope that journal will soar higher with the passing time."

Dr Saumya Navit
Professor and Head
Department of Pediatric Dentistry
Saraswati Dental College
On Sep 2018

Dr. Arunava Biswas

"My sincere attachment with JCDR as an author as well as reviewer is a learning experience . Their systematic approach in publication of article in various categories is really praiseworthy.
Their prompt and timely response to review's query and the manner in which they have set the reviewing process helps in extracting the best possible scientific writings for publication.
It's a honour and pride to be a part of the JCDR team. My very best wishes to JCDR and hope it will sparkle up above the sky as a high indexed journal in near future."

Dr. Arunava Biswas
MD, DM (Clinical Pharmacology)
Assistant Professor
Department of Pharmacology
Calcutta National Medical College & Hospital , Kolkata

Dr. C.S. Ramesh Babu
" Journal of Clinical and Diagnostic Research (JCDR) is a multi-specialty medical and dental journal publishing high quality research articles in almost all branches of medicine. The quality of printing of figures and tables is excellent and comparable to any International journal. An added advantage is nominal publication charges and monthly issue of the journal and more chances of an article being accepted for publication. Moreover being a multi-specialty journal an article concerning a particular specialty has a wider reach of readers of other related specialties also. As an author and reviewer for several years I find this Journal most suitable and highly recommend this Journal."
Best regards,
C.S. Ramesh Babu,
Associate Professor of Anatomy,
Muzaffarnagar Medical College,
On Aug 2018

Dr. Arundhathi. S
"Journal of Clinical and Diagnostic Research (JCDR) is a reputed peer reviewed journal and is constantly involved in publishing high quality research articles related to medicine. Its been a great pleasure to be associated with this esteemed journal as a reviewer and as an author for a couple of years. The editorial board consists of many dedicated and reputed experts as its members and they are doing an appreciable work in guiding budding researchers. JCDR is doing a commendable job in scientific research by promoting excellent quality research & review articles and case reports & series. The reviewers provide appropriate suggestions that improve the quality of articles. I strongly recommend my fraternity to encourage JCDR by contributing their valuable research work in this widely accepted, user friendly journal. I hope my collaboration with JCDR will continue for a long time".

Dr. Arundhathi. S
MBBS, MD (Pathology),
Sanjay Gandhi institute of trauma and orthopedics,
On Aug 2018

Dr. Mamta Gupta,
"It gives me great pleasure to be associated with JCDR, since last 2-3 years. Since then I have authored, co-authored and reviewed about 25 articles in JCDR. I thank JCDR for giving me an opportunity to improve my own skills as an author and a reviewer.
It 's a multispecialty journal, publishing high quality articles. It gives a platform to the authors to publish their research work which can be available for everyone across the globe to read. The best thing about JCDR is that the full articles of all medical specialties are available as pdf/html for reading free of cost or without institutional subscription, which is not there for other journals. For those who have problem in writing manuscript or do statistical work, JCDR comes for their rescue.
The journal has a monthly publication and the articles are published quite fast. In time compared to other journals. The on-line first publication is also a great advantage and facility to review one's own articles before going to print. The response to any query and permission if required, is quite fast; this is quite commendable. I have a very good experience about seeking quick permission for quoting a photograph (Fig.) from a JCDR article for my chapter authored in an E book. I never thought it would be so easy. No hassles.
Reviewing articles is no less a pain staking process and requires in depth perception, knowledge about the topic for review. It requires time and concentration, yet I enjoy doing it. The JCDR website especially for the reviewers is quite user friendly. My suggestions for improving the journal is, more strict review process, so that only high quality articles are published. I find a a good number of articles in Obst. Gynae, hence, a new journal for this specialty titled JCDR-OG can be started. May be a bimonthly or quarterly publication to begin with. Only selected articles should find a place in it.
An yearly reward for the best article authored can also incentivize the authors. Though the process of finding the best article will be not be very easy. I do not know how reviewing process can be improved. If an article is being reviewed by two reviewers, then opinion of one can be communicated to the other or the final opinion of the editor can be communicated to the reviewer if requested for. This will help one’s reviewing skills.
My best wishes to Dr. Hemant Jain and all the editorial staff of JCDR for their untiring efforts to bring out this journal. I strongly recommend medical fraternity to publish their valuable research work in this esteemed journal, JCDR".

Dr. Mamta Gupta
(Ex HOD Obs &Gynae, Hindu Rao Hospital and associated NDMC Medical College, Delhi)
Aug 2018

Dr. Rajendra Kumar Ghritlaharey

"I wish to thank Dr. Hemant Jain, Editor-in-Chief Journal of Clinical and Diagnostic Research (JCDR), for asking me to write up few words.
Writing is the representation of language in a textual medium i e; into the words and sentences on paper. Quality medical manuscript writing in particular, demands not only a high-quality research, but also requires accurate and concise communication of findings and conclusions, with adherence to particular journal guidelines. In medical field whether working in teaching, private, or in corporate institution, everyone wants to excel in his / her own field and get recognised by making manuscripts publication.

Authors are the souls of any journal, and deserve much respect. To publish a journal manuscripts are needed from authors. Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards. Both ways its true "No authors-No manuscripts-No journals" and "No journals–No manuscripts–No authors". Reviewing a manuscript is also a very responsible and important task of any peer-reviewed journal and to be taken seriously. It needs knowledge on the subject, sincerity, honesty and determination. Although the process of reviewing a manuscript is a time consuming task butit is expected to give one's best remarks within the time frame of the journal.
Salient features of the JCDR: It is a biomedical, multidisciplinary (including all medical and dental specialities), e-journal, with wide scope and extensive author support. At the same time, a free text of manuscript is available in HTML and PDF format. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb 2007 of its first issue, it contained 5 articles only, and now in its recent volume published in April 2011, it contained 67 manuscripts. This e-journal is fulfilling the commitments and objectives sincerely, (as stated by Editor-in-chief in his preface to first edition) i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help. JCDR provides authors help in this regards.
Timely publication of journal: Publication of manuscripts and bringing out the issue in time is one of the positive aspects of JCDR and is possible with strong support team in terms of peer reviewers, proof reading, language check, computer operators, etc. This is one of the great reasons for authors to submit their work with JCDR. Another best part of JCDR is "Online first Publications" facilities available for the authors. This facility not only provides the prompt publications of the manuscripts but at the same time also early availability of the manuscripts for the readers.
Indexation and online availability: Indexation transforms the journal in some sense from its local ownership to the worldwide professional community and to the public.JCDR is indexed with Embase & EMbiology, Google Scholar, Index Copernicus, Chemical Abstracts Service, Journal seek Database, Indian Science Abstracts, to name few of them. Manuscriptspublished in JCDR are available on major search engines ie; google, yahoo, msn.
In the era of fast growing newer technologies, and in computer and internet friendly environment the manuscripts preparation, submission, review, revision, etc and all can be done and checked with a click from all corer of the world, at any time. Of course there is always a scope for improvement in every field and none is perfect. To progress, one needs to identify the areas of one's weakness and to strengthen them.
It is well said that "happy beginning is half done" and it fits perfectly with JCDR. It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb 2007. This had been made possible due to the efforts and the hard work put in it. The way the JCDR is improving with every new volume, with good quality original manuscripts, makes it a quality journal for readers. I must thank and congratulate Dr Hemant Jain, Editor-in-Chief JCDR and his team for their sincere efforts, dedication, and determination for making JCDR a fast growing journal.
Every one of us: authors, reviewers, editors, and publisher are responsible for enhancing the stature of the journal. I wish for a great success for JCDR."

Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
On May 11,2011

Dr. Shankar P.R.

"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
Most of the manuscripts are published within 3 to 4 months of their submission if they are found to be suitable after the review process. JCDR is published bimonthly and the accepted articles were usually published in the next issue. Recently, due to the increased volume of the submissions, the review process has become slower and it ?? Section can take from 4 to 6 months for the articles to be reviewed. The journal has an extensive author support system and it has recently introduced a paid expedited review process. The journal also mentions the average time for processing the manuscript under different submission systems - regular submission and expedited review.
Strengths of the journal: The journal has an online first facility in which the accepted manuscripts may be published on the website before being included in a regular issue of the journal. This cuts down the time between their acceptance and the publication. The journal is indexed in many databases, though not in PubMed. The editorial board should now take steps to index the journal in PubMed. The journal has a system of notifying readers through e-mail when a new issue is released. Also, the articles are available in both the HTML and the PDF formats. I especially like the new and colorful page format of the journal. Also, the access statistics of the articles are available. The prepublication and the manuscript tracking system are also helpful for the authors.
Areas for improvement: In certain cases, I felt that the peer review process of the manuscripts was not up to international standards and that it should be strengthened. Also, the number of manuscripts in an issue is high and it may be difficult for readers to go through all of them. The journal can consider tightening of the peer review process and increasing the quality standards for the acceptance of the manuscripts. I faced occasional problems with the online manuscript submission (Pre-publishing) system, which have to be addressed.
Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work."

Dr. P. Ravi Shankar
KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
On April 2011

Dear team JCDR, I would like to thank you for the very professional and polite service provided by everyone at JCDR. While i have been in the field of writing and editing for sometime, this has been my first attempt in publishing a scientific paper.Thank you for hand-holding me through the process.

Dr. Anuradha
On Jan 2020

Important Notice

Case report
Year : 2008 | Month : June | Volume : 2 | Issue : 3 | Page : 867 - 870 Full Version

Primary Pyomyositis Of Paraspinal Muscles: A Rare Location

Published: June 1, 2008 | DOI:
Correspondence Address :
Dr. Tauro Leo Francis Department of General Surgery Fr. Muller Medical College Hospital Kankanady, Mangalore – 575002 (D.K.), Karnataka.Ph. No: Hosp: (0824) 2436301, Res: (0824) 2224911 E-Mail:


Primary pyomyositis is a rare, sub-acute, primary muscle infection that is probably the result of a transient bacteraemia in most patients. It is rarely reported in temperate climates. The quadriceps, gluteal and iliopsoas muscles are the most commonly affected anatomic sites. A case of primary pyomyositis within the paraspinal muscles of a 30-year-old man is reported with details of diagnostic evaluation, and medical and surgical treatment of the condition. Early diagnosis and complete drainage of any abscess cavity combined with appropriate antibiotic therapy, remains the mainstay of treatment. Most patients have complete recovery, with no long term sequelae. Failure to recognize this clinical entity can lead to diagnostic delay and inappropriate management.


Pyomyositis, Para spinal abscess, tropical pyomyositis

Primary pyomyositis is a rare, sub acute, primary bacterial infection of the skeletal muscles. It is not secondary to a contiguous infection of the skin, bone or soft tissues.(1) (2) It is also called tropical myositis, infective myositis, pyogenic myositis, suppurative myositis, myositis purulenta tropica, epidemic abscess or bacterial pyomyositis.(2) The quadriceps, gluteal and iliopsoas muscles are the most commonly affected anatomic sites. Staphylococcus aureus is the culpable organism in more than 75% of the cases. There are three consecutive stages of the disease: diffuse muscle infection, abscess formation, and sepsis. Magnetic Resonance Imaging is the preferred diagnostic imaging modality. Early diagnosis and complete drainage of any abscess cavity, combined with appropriate antibiotic therapy, remains the mainstay of treatment.(1) (2) We report a young male patient with para spinal pyomyositis presenting as back pain.

Case Report

A 30 year-old-male patient was admitted with severe back pain and high grade fever for three days. The patient was not a known diabetic, and had no prior history of trauma to the back muscles. On general physical examination, the patient was febrile, with a pulse rate of 90/min. Local examination revealed diffuse erythema with subcutaneous oedema in the right para spinal region, extending from the right scapular region to the iliac crest. There was local rise of temperature, and tenderness. Fluctuation was absent. The systemic examination was unremarkable. There was no evidence of any focus of infection in the urinary tract, dental or ENT regions. His haematological examination revealed haemoglobin 11g/dl, total count 16,800/mm3, N-84%, L-10%, E-6%, and ESR- 32mm in the first hour. Urine analysis detected proteinuria (300mg/dl). Liver function tests were normal, except for a marginal raise in the bilirubin and alkaline phosphatase levels. His blood urea nitrogen and serum creatinine were within normal limits. The peripheral smear revealed reactive neutrophilia with neutrophils showing toxic change. There were no haemoparasites detected. Serum CK-MB 12U/L. ELISA for HIV, and HBsAg were non-reactive. Ultra sound abdomen revealed 6mm calculus in the lower pole of left kidney, and mild right side pleural effusion. Musculoskeletal ultrasonography (USG) of the back revealed evidence of inter and intramuscular collection in the right para-spinal area, and USG- guided aspiration yielded pus. His chest x-ray was normal. X-ray of the thoraco-lumbar spine showed minimal scoliosis on the right side, without any bony lesions (Table/Fig 1). Para spinal pyomyositis was drained by multiple transverse incisions under general anaesthesia(Table/Fig 2). Pus culture isolated coagulase negative staphylococci which were sensitive to amoxyclav, gentamicin, amikacin, ciprofloxacin, cefotaxime, ceftriaxone and cefadroxil, were grown in aerobic culture media. AFB stain was negative. Histopathological examination of the curettage specimen of the abscess cavity revealed features suggestive of pyogenic abscess, without any evidence of tuberculosis.

Parenteral Ceftriaxone with Amikacin was administered for 10 days. The patient was subjected to daily cleaning and dressing of the wounds, and was discharged on oral cefadroxil for 4 weeks.
After 6 months follow up, the patient remains asymptomatic with a full range of spinal movements, without any residual disability. The repeat X-ray of his spine revealed disappearance of scoliosis.


Traquair(3) credited Virchow for the earliest mention of pyomyositis; however, Scriba in 1885, was probably responsible for the first true description. Primary Pyomyositis (PPM) is a rare, sub acute, muscle infection that is probably the result of transient bacteraemia in most patients. It has been seen in all age groups, but it is most common in the first and second decades of life, with slight predominance in males.(2)(4) PPM commonly manifests as a local abscess, but may also present as a diffuse inflammatory or a rapidly progressing myonecrotic process. PPM can involve any muscle group in the body: a single muscle is usually affected, although 11% to 43% of the patients have involvement of multiple sites.(4) Because of its rarity and often vague clinical presentation, it is unlikely to be considered during the initial diagnosis. Moreover, diagnosis may be delayed if the affected muscle is deeply situated and local signs are not apparent. This delay in diagnosis may result in a compartmental syndrome,(5) extension into and destruction of an adjacent joint, (6) sepsis, and occasionally death. Lung and brain abscesses, pericarditis, myocarditis, endocarditis and renal failure have been reported. (7)

The aetiology of PPM remains unclear. The infection is believed to be a complication of transient bacteraemia, because, in the vast majority of the patients, it develops without any penetrating injuries or any other clear portals of entry.(4) The rarity of the infection is attributed to an assumed resistance of skeletal muscles to bacteraemic episodes. Trauma to the affected muscle resulting in alteration of the muscle structure has been proposed as a possible aetiology. PPM has three distinct stages, which represent a gradual progression from diffuse muscle infection to focal abscess formation, to a septic state.(2) (4)

Stage 1: Diffuse muscle infection - Local signs of inflammation are absent initially due to deep seated infection, but pain and even systemic signs of infection are present.

Stage 2: Muscle abscess formation is associated with local and systemic manifestations of infection. A tender soft tissue mass can be palpated, and the affected muscle is typically described as having a firm, wooden texture. The overlying skin is swollen, erythematous and warm. The patient may have exquisite tenderness and fluctuance of the involved area, obvious functional disability, and occasionally frank septicaemia.

Stage 3: Sepsis: It includes signs of toxicity and septic shock. This late stage of the disease is characterized by severe pain, local signs of infection and systemic manifestations of sepsis, all of which require urgent intervention. Because of its clinical manifestations, PPM has been confused with muscle strain, thrombophlebitis, cellulitis, bursitis, contusion, haematoma, Perthes’ disease, septic arthritis, osteomyelitis, rheumatoid arthritis and soft tissue sarcoma. (2),(3),(4) PPM of iliopsoas or involvement of the abdominal wall, especially the right lower quadrant, may be confused with acute appendicitis and may lead to unnecessary laparotomy. (2)

Imaging studies like plain radiography is the appropriate study for the initial screening to rule out primary bone lesions such as sub-acute osteomyelitis or primary bone sarcoma that can mimic the clinical presentation of PPM. Computerized tomography provides better delineation of muscle structure than plain radiography, and therefore enables the diagnosis of the muscle abscess. Ultrasonography has also been used for the diagnosis of PPM. The typical findings are a bulky muscle with abnormal echo text


Cecil M, Dimar JR 2nd. Para spinal pyomyositis, a rare cause of severe back pain: case report and review of literature. Am J Orthop. 1997; 26:785-7.
Bickels J, Ben-Sira L, Kessler A, Wientroub S. Primary Pyomyositis. J Bone Joint Surg Am 2002; 84:2277-86.
Hall RL, Callaghan JJ, Moloney E, Martinez S, Harrelson JM. Pyomyositis in a temperate climate. Presentation, diagnosis and treatment. J Bone Joint Surg Am 1990; 72:1240-44.
Chiedozi LC. Pyomyositis. Review of 205 cases in 112 patients. Am J Surg 1979; 137:255-59.
Harrington P, Scott B, Chetcuti P. Multifocal streptococcal pyomyositis complicated by acute compartmental syndrome. J Pediatr Orthop B 2001; 10:120-22.
Freedman KB, Hahn GV, Fitzgerald RH Jr. Unusual case of septic arthritis of the hip: spread from adjacent adductor pyomyositis. J Arthroplasty. 1999; 14:886-91.
Immerman RP, Greenman RL. Toxic shock syndrome associated with pyomyositis caused by a strain of staphylococcus aureus that does not produce toxic shock syndrome toxin-1. J Infect Dis 1987; 156:505-7.

JCDR is now Monthly and more widely Indexed .
  • Emerging Sources Citation Index (Web of Science, thomsonreuters)
  • Index Copernicus ICV 2017: 134.54
  • Academic Search Complete Database
  • Directory of Open Access Journals (DOAJ)
  • Embase
  • EBSCOhost
  • Google Scholar
  • HINARI Access to Research in Health Programme
  • Indian Science Abstracts (ISA)
  • Journal seek Database
  • Google
  • Popline (reproductive health literature)