Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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On Sep 2018

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On Sep 2018

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"Journal of Clinical and Diagnostic Research is at present a well-known Indian originated scientific journal which started with a humble beginning. I have been associated with this journal since many years. I appreciate the Editor, Dr. Hemant Jain, for his constant effort in bringing up this journal to the present status right from the scratch. The journal is multidisciplinary. It encourages in publishing the scientific articles from postgraduates and also the beginners who start their career. At the same time the journal also caters for the high quality articles from specialty and super-specialty researchers. Hence it provides a platform for the scientist and researchers to publish. The other aspect of it is, the readers get the information regarding the most recent developments in science which can be used for teaching, research, treating patients and to some extent take preventive measures against certain diseases. The journal is contributing immensely to the society at national and international level."

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On Aug 2018

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Dr. Arundhathi. S
MBBS, MD (Pathology),
Sanjay Gandhi institute of trauma and orthopedics,
On Aug 2018

Dr. Mamta Gupta,
"It gives me great pleasure to be associated with JCDR, since last 2-3 years. Since then I have authored, co-authored and reviewed about 25 articles in JCDR. I thank JCDR for giving me an opportunity to improve my own skills as an author and a reviewer.
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Reviewing articles is no less a pain staking process and requires in depth perception, knowledge about the topic for review. It requires time and concentration, yet I enjoy doing it. The JCDR website especially for the reviewers is quite user friendly. My suggestions for improving the journal is, more strict review process, so that only high quality articles are published. I find a a good number of articles in Obst. Gynae, hence, a new journal for this specialty titled JCDR-OG can be started. May be a bimonthly or quarterly publication to begin with. Only selected articles should find a place in it.
An yearly reward for the best article authored can also incentivize the authors. Though the process of finding the best article will be not be very easy. I do not know how reviewing process can be improved. If an article is being reviewed by two reviewers, then opinion of one can be communicated to the other or the final opinion of the editor can be communicated to the reviewer if requested for. This will help one’s reviewing skills.
My best wishes to Dr. Hemant Jain and all the editorial staff of JCDR for their untiring efforts to bring out this journal. I strongly recommend medical fraternity to publish their valuable research work in this esteemed journal, JCDR".

Dr. Mamta Gupta
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Aug 2018

Dr. Rajendra Kumar Ghritlaharey

"I wish to thank Dr. Hemant Jain, Editor-in-Chief Journal of Clinical and Diagnostic Research (JCDR), for asking me to write up few words.
Writing is the representation of language in a textual medium i e; into the words and sentences on paper. Quality medical manuscript writing in particular, demands not only a high-quality research, but also requires accurate and concise communication of findings and conclusions, with adherence to particular journal guidelines. In medical field whether working in teaching, private, or in corporate institution, everyone wants to excel in his / her own field and get recognised by making manuscripts publication.

Authors are the souls of any journal, and deserve much respect. To publish a journal manuscripts are needed from authors. Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards. Both ways its true "No authors-No manuscripts-No journals" and "No journals–No manuscripts–No authors". Reviewing a manuscript is also a very responsible and important task of any peer-reviewed journal and to be taken seriously. It needs knowledge on the subject, sincerity, honesty and determination. Although the process of reviewing a manuscript is a time consuming task butit is expected to give one's best remarks within the time frame of the journal.
Salient features of the JCDR: It is a biomedical, multidisciplinary (including all medical and dental specialities), e-journal, with wide scope and extensive author support. At the same time, a free text of manuscript is available in HTML and PDF format. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb 2007 of its first issue, it contained 5 articles only, and now in its recent volume published in April 2011, it contained 67 manuscripts. This e-journal is fulfilling the commitments and objectives sincerely, (as stated by Editor-in-chief in his preface to first edition) i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help. JCDR provides authors help in this regards.
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In the era of fast growing newer technologies, and in computer and internet friendly environment the manuscripts preparation, submission, review, revision, etc and all can be done and checked with a click from all corer of the world, at any time. Of course there is always a scope for improvement in every field and none is perfect. To progress, one needs to identify the areas of one's weakness and to strengthen them.
It is well said that "happy beginning is half done" and it fits perfectly with JCDR. It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb 2007. This had been made possible due to the efforts and the hard work put in it. The way the JCDR is improving with every new volume, with good quality original manuscripts, makes it a quality journal for readers. I must thank and congratulate Dr Hemant Jain, Editor-in-Chief JCDR and his team for their sincere efforts, dedication, and determination for making JCDR a fast growing journal.
Every one of us: authors, reviewers, editors, and publisher are responsible for enhancing the stature of the journal. I wish for a great success for JCDR."

Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
On May 11,2011

Dr. Shankar P.R.

"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
Most of the manuscripts are published within 3 to 4 months of their submission if they are found to be suitable after the review process. JCDR is published bimonthly and the accepted articles were usually published in the next issue. Recently, due to the increased volume of the submissions, the review process has become slower and it ?? Section can take from 4 to 6 months for the articles to be reviewed. The journal has an extensive author support system and it has recently introduced a paid expedited review process. The journal also mentions the average time for processing the manuscript under different submission systems - regular submission and expedited review.
Strengths of the journal: The journal has an online first facility in which the accepted manuscripts may be published on the website before being included in a regular issue of the journal. This cuts down the time between their acceptance and the publication. The journal is indexed in many databases, though not in PubMed. The editorial board should now take steps to index the journal in PubMed. The journal has a system of notifying readers through e-mail when a new issue is released. Also, the articles are available in both the HTML and the PDF formats. I especially like the new and colorful page format of the journal. Also, the access statistics of the articles are available. The prepublication and the manuscript tracking system are also helpful for the authors.
Areas for improvement: In certain cases, I felt that the peer review process of the manuscripts was not up to international standards and that it should be strengthened. Also, the number of manuscripts in an issue is high and it may be difficult for readers to go through all of them. The journal can consider tightening of the peer review process and increasing the quality standards for the acceptance of the manuscripts. I faced occasional problems with the online manuscript submission (Pre-publishing) system, which have to be addressed.
Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work."

Dr. P. Ravi Shankar
KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
On April 2011

Dear team JCDR, I would like to thank you for the very professional and polite service provided by everyone at JCDR. While i have been in the field of writing and editing for sometime, this has been my first attempt in publishing a scientific paper.Thank you for hand-holding me through the process.

Dr. Anuradha
On Jan 2020

Important Notice

Case report
Year : 2012 | Month : February | Volume : 6 | Issue : 1 | Page : 106 - 107 Full Version

Thyroid Abscess in Immuno Compromised Patient: A Case Report

Published: February 1, 2012 | DOI:
Yamanur P. Lamani, S.I. Basarkod, S.R. Telkar, B.V. Goudar, Uday Ambi

1. Assistant Professor, Dept of Surgery, SN Medical College, Navanagar, Bagalkot. 2. Associate Professor, Dept of Surgery, SN Medical College, Navanagar, Bagalkot. 3. Assistant Professor, Dept of Surgery, SN Medical College, Navanagar, Bagalkot. 4. Associate Professor, Dept of Surgery, SN Medical College, Navanagar, Bagalkot. 5. Assistant Professor, Dept of Anaesthesiology, SN Medical College, Navanagar, Bagalkot.

Correspondence Address :
Dr. Y.P. Lamani
Department of Surgery
SN Medical College, Navanagar, Bagalkot
Phone: 9986293013


Thyroid abscess is a rare condition of the thyroid gland. The ability of thyroid gland is to resist infection which is well known and the infection in thyroid gland is rare, particularly so with the advent of widespread usage of antibiotics. Thyroid abscess represents only 0.1 to 0.7% of surgically treated thyroid pathologies. We report here a case of adult female with HIV infection who presented with thyroid abscess.


Abscess, Staphyloccocal aureus, Thyroditis

Acute suppurative thyroditis(AST) leading to thyroid abscess is a rare clinical entity. AST affects specially patients with pre-existing thyroid gland pathology and in childhood it is associated with local anatomic defects. Because of its rarity and unusual clinical features, the diagnosis of thyroid abscess is often delayed. Thyroid abscess is infrequently encountered condition with a rarity that is attributed to anatomic and physiologic characteristics of the gland that imparts a unique quality of infection of resistance. When discovered a thyroid abscess it presents as acutely as a painful swelling. The differential diagnosis for a painful thyroid is limited, with sub-cute and chronic thyroiditis being the most often encountered process.

Case Report

A 28-year old female presented with an enlarging painful neck swelling of one month duration. There was a history of mild to moderate degree fever and odonophagia since the onset of the swelling. Pain was described as constant and radiating to the occipital region. On admission patient was febrile, tachacycardia but no evidence of respiratory distress. Examination of the neck reveled a swelling occupying in the region of thyroid more prominent on the right than on the left. The swelling was tender and fluctuant, movement with deglutition was present and there was no movement with protrusion of tongue. No cervical lymphadenopathy was found. Laboratory investigations revealed laeukocyte count of more than 15000 with 80% of polymorphs; haemoglobin of 9% with HIV infection.USG neck demonstrated a cystic swelling in the right lobe of the thyroid suggestive of thyroid abscess. Needle aspiration of the swelling obtained thick yellow pus and culture yielded Staphylococcal aureus, thyroid function test was normal. Patient underwent ultrasound guided byaspiration with wide bore needle, and given intravenous antibiotics according to the culture sensitivity report. Patient was followed up after one month there was gross regression in the size of the swelling and pain.


Thyroid abscess is an infrequently encountered condition, with a rarity that is attributable to the anatomic and physiologiccharacteristics of the gland that imparts a unique quality of infection resistance (1). The remarkable resistance of the thyroid gland to infection is attributable to many factors. A prosperous lymphatic and vascular supply, well developed capsule, high iodine content of the gland havevarious mechanisms suggested to account for this relative resistance to infection (2).

Abscess formation of thyroid most commonly arises in pediatric population in the setting of anatomic anomalies of the hypopharyngeal region, leading to the development of a pyriform sinus fistula. In the adult population, multiple etiologies have been proposed. Abscess development secondary to direct trauma from foreign bodies, such as fine needle aspiration, fish bone and chicken bone penetration have been described, as well as extension from neighboring anatomic structures (3),(4),(5). However hematogenous spreading from a distant site is considered to be the most common cause of infection,eventhough the exact infectious source or pathology is frequently unknown (6). The most common causative organisms have historically been Staphylococci and Streptococci species and cultures are moreoften polymicrobials,other organisms isolated such as Acinatobacter, Mycobacterium, Coccidiodes, Pseudomonas, Salmonella, Eikenella, Clostridium, Nocordia, Pnemocystis carnii, Hemophilus and Candida species have been identified, although they are most commonly associated with immunosuppressed patients (6), (8),(9),(10),(11),(12),(13),(14),(15),(16). Acute suppurative thyroiditis has also been associated with immunsuppression, especially human immune-deficiency virus (15). Patients infected with HIV, however still develop Mycobacterial and fungal thyroid infection with some regularity. AST has been associated with transient hyperthyroidism and was caused by Pasteurella multocida (7).

Because of its rarity the incidence of thyroid abscess formation is difficult to identify. That data are equivocal regarding whether thyroid abscesses occur more frequently in men or women. Hazard et al (3) observed a more common occurance in the women in the age range of 20-40 years, where as large reviews by Yu et al (17) and Burger et al (18) both revealed a more uniformed distribution among the sexes. Acute suppurative thyroiditis responds well to antibiotics (Intravenous) with or without incision drainage of the abscesses and rarely causes external fistula. Our patient was a female aged 28 years with immunocompromised state presented with painful swelling in the region of thyroid, underwent USG guided aspiration of the pus and culture showed Staphylococcal aureus and she was managed with intravenous antibiotics for 7days. Follow up done after one month there was complete regression of the swelling and pain.


Herdon, Mark D, Christie, et al. Thyroid abscess: Case report and review of literature. Am Surg 2007; 73:725-28.
Schweitzer VG, Olson NR. Thyroid abscess Otolaryngol Head Neck Surg 1981; Mar-Apr, 89(2):226-29.
Hazard JB. Thyroiditis: A review – Part I. Am J Clin Pathol 1995; 25: 289-98.
Coret A.Heyman Z. Bendet E, et al. Thyroid abscess resulting from transoesophageal migration of a fish bone: Ultrasound appearance. J Clin Ultrasound 1993; 21:152-54.
Yung BC, Loke TK. Fan WC. et al. Acute suppurative thyroiditis due to foreign body induced retropharyngeal presented as thyrotoxicosis. Clin Nucl Med 2000; 35:249-52.
Jacobs A, Gros DC .Gradon JD. Thyroid abscess due to Acinetobacter calcoaceticus: Case report and review of the causes of and current management strategies of thyroid abscesses. South Med J 2003; 96: 300-07.
McLaughlin SA, Smith SL,Meek SE 2006 Acute suppurative thyroiditis caused by Pasturella multocida and associated with thyrotoxicosis. Thyroid 16: 307-10.
Pandita D, Carson PJ. Thyroid abscess caused by Mycobacterium chelonae. Clin Infect Dis 1999; 28:1183-84.
Smilack JD, Argueta R. Coccidial infection of the thyroid. Lntern Med 1998; 158: 89-92.
Ameh EA. Sabo SY, Nmadu PT. The risk of infective thyroiditis in nodular goiter. East Afr Med J 1998; 75: 425-27.
Gudipati S, Westblom TU. Salmonellosis initially seen as thyroid abscess. Head Neck 1991; 13:153-55.
Vichyanoud P, Howard CP,Olson LC. Eikenella corrodens as a cause of thyroid abscess. Am J Dis Child 1983; 137:971-3.
Michel RG, Hall DM, Woodard BH. Gas forming suppurative thyroiditis. Ear Nose Throat J 1981; 60:127-30.
Vandome A. Pageaux GP. Bismuth M et al. Nocordiosis revealed by thyroid abscess in a liver–kidney transplant recipient. Transplant Int 2001; 14:202-04.
Golshan MM. MacHenry CR. DeVente J et al.Acute suppurative thyroiditis and necrosis of the thyroid gland: A rare endocrine manifestation of acquired immunodeficiency syndrome. Surg 1997; 121:593-96.
Diez O.Anorbe E, Asia P, et al. Acute suppurative thyroiditis secondary to pyriform sinus fistula: A case report. Eur J Radiol 1998; 29:25-7.
Yu EH. Ko WC. Chuang YC, et al. Suppurative Acinatobacter baumanii thyroiditis with bacteremic pneumonia: A case report and review. Clin Infect Dis 1998; 27: 1286-90.
Berger SA, Zonszein J, Villamena P. Infectious diseases of thyroid gland. Rev Infect Dis 1983; 5: 108-22.

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[Table / Fig - 1]
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ID: JCDR/2012/3533:1880


Date of Submission: Nov 02, 2011
Date of Peer Review: Dec 11, 2011
Date of Acceptance: Dec 22, 2011
Date of Publishing: Feb 15, 2012

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