Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

Users Online : 35858

AbstractCase ReportDiscussionConclusionReferencesDOI and Others
Readers' Comments (0) Article in PDF Audio Visual Citation Manager Article Statistics Link to PUBMED Print this Article Send to a Friend
Advertisers Access Statistics Resources

Dr Bhanu K Bhakhri

"The Journal of Clinical and Diagnostic Research (JCDR) has been in operation since almost a decade. It has contributed a huge number of peer reviewed articles, across a spectrum of medical disciplines, to the medical literature.
Its wide based indexing and open access publications attracts many authors as well as readers
For authors, the manuscripts can be uploaded online through an easily navigable portal, on other hand, reviewers appreciate the systematic handling of all manuscripts. The way JCDR has emerged as an effective medium for publishing wide array of observations in Indian context, I wish the editorial team success in their endeavour"

Dr Bhanu K Bhakhri
Faculty, Pediatric Medicine
Super Speciality Paediatric Hospital and Post Graduate Teaching Institute, Noida
On Sep 2018

Dr Mohan Z Mani

"Thank you very much for having published my article in record time.I would like to compliment you and your entire staff for your promptness, courtesy, and willingness to be customer friendly, which is quite unusual.I was given your reference by a colleague in pathology,and was able to directly phone your editorial office for clarifications.I would particularly like to thank the publication managers and the Assistant Editor who were following up my article. I would also like to thank you for adjusting the money I paid initially into payment for my modified article,and refunding the balance.
I wish all success to your journal and look forward to sending you any suitable similar article in future"

Dr Mohan Z Mani,
Professor & Head,
Department of Dematolgy,
Believers Church Medical College,
Thiruvalla, Kerala
On Sep 2018

Prof. Somashekhar Nimbalkar

"Over the last few years, we have published our research regularly in Journal of Clinical and Diagnostic Research. Having published in more than 20 high impact journals over the last five years including several high impact ones and reviewing articles for even more journals across my fields of interest, we value our published work in JCDR for their high standards in publishing scientific articles. The ease of submission, the rapid reviews in under a month, the high quality of their reviewers and keen attention to the final process of proofs and publication, ensure that there are no mistakes in the final article. We have been asked clarifications on several occasions and have been happy to provide them and it exemplifies the commitment to quality of the team at JCDR."

Prof. Somashekhar Nimbalkar
Head, Department of Pediatrics, Pramukhswami Medical College, Karamsad
Chairman, Research Group, Charutar Arogya Mandal, Karamsad
National Joint Coordinator - Advanced IAP NNF NRP Program
Ex-Member, Governing Body, National Neonatology Forum, New Delhi
Ex-President - National Neonatology Forum Gujarat State Chapter
Department of Pediatrics, Pramukhswami Medical College, Karamsad, Anand, Gujarat.
On Sep 2018

Dr. Kalyani R

"Journal of Clinical and Diagnostic Research is at present a well-known Indian originated scientific journal which started with a humble beginning. I have been associated with this journal since many years. I appreciate the Editor, Dr. Hemant Jain, for his constant effort in bringing up this journal to the present status right from the scratch. The journal is multidisciplinary. It encourages in publishing the scientific articles from postgraduates and also the beginners who start their career. At the same time the journal also caters for the high quality articles from specialty and super-specialty researchers. Hence it provides a platform for the scientist and researchers to publish. The other aspect of it is, the readers get the information regarding the most recent developments in science which can be used for teaching, research, treating patients and to some extent take preventive measures against certain diseases. The journal is contributing immensely to the society at national and international level."

Dr Kalyani R
Professor and Head
Department of Pathology
Sri Devaraj Urs Medical College
Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka
On Sep 2018

Dr. Saumya Navit

"As a peer-reviewed journal, the Journal of Clinical and Diagnostic Research provides an opportunity to researchers, scientists and budding professionals to explore the developments in the field of medicine and dentistry and their varied specialities, thus extending our view on biological diversities of living species in relation to medicine.
‘Knowledge is treasure of a wise man.’ The free access of this journal provides an immense scope of learning for the both the old and the young in field of medicine and dentistry as well. The multidisciplinary nature of the journal makes it a better platform to absorb all that is being researched and developed. The publication process is systematic and professional. Online submission, publication and peer reviewing makes it a user-friendly journal.
As an experienced dentist and an academician, I proudly recommend this journal to the dental fraternity as a good quality open access platform for rapid communication of their cutting-edge research progress and discovery.
I wish JCDR a great success and I hope that journal will soar higher with the passing time."

Dr Saumya Navit
Professor and Head
Department of Pediatric Dentistry
Saraswati Dental College
On Sep 2018

Dr. Arunava Biswas

"My sincere attachment with JCDR as an author as well as reviewer is a learning experience . Their systematic approach in publication of article in various categories is really praiseworthy.
Their prompt and timely response to review's query and the manner in which they have set the reviewing process helps in extracting the best possible scientific writings for publication.
It's a honour and pride to be a part of the JCDR team. My very best wishes to JCDR and hope it will sparkle up above the sky as a high indexed journal in near future."

Dr. Arunava Biswas
MD, DM (Clinical Pharmacology)
Assistant Professor
Department of Pharmacology
Calcutta National Medical College & Hospital , Kolkata

Dr. C.S. Ramesh Babu
" Journal of Clinical and Diagnostic Research (JCDR) is a multi-specialty medical and dental journal publishing high quality research articles in almost all branches of medicine. The quality of printing of figures and tables is excellent and comparable to any International journal. An added advantage is nominal publication charges and monthly issue of the journal and more chances of an article being accepted for publication. Moreover being a multi-specialty journal an article concerning a particular specialty has a wider reach of readers of other related specialties also. As an author and reviewer for several years I find this Journal most suitable and highly recommend this Journal."
Best regards,
C.S. Ramesh Babu,
Associate Professor of Anatomy,
Muzaffarnagar Medical College,
On Aug 2018

Dr. Arundhathi. S
"Journal of Clinical and Diagnostic Research (JCDR) is a reputed peer reviewed journal and is constantly involved in publishing high quality research articles related to medicine. Its been a great pleasure to be associated with this esteemed journal as a reviewer and as an author for a couple of years. The editorial board consists of many dedicated and reputed experts as its members and they are doing an appreciable work in guiding budding researchers. JCDR is doing a commendable job in scientific research by promoting excellent quality research & review articles and case reports & series. The reviewers provide appropriate suggestions that improve the quality of articles. I strongly recommend my fraternity to encourage JCDR by contributing their valuable research work in this widely accepted, user friendly journal. I hope my collaboration with JCDR will continue for a long time".

Dr. Arundhathi. S
MBBS, MD (Pathology),
Sanjay Gandhi institute of trauma and orthopedics,
On Aug 2018

Dr. Mamta Gupta,
"It gives me great pleasure to be associated with JCDR, since last 2-3 years. Since then I have authored, co-authored and reviewed about 25 articles in JCDR. I thank JCDR for giving me an opportunity to improve my own skills as an author and a reviewer.
It 's a multispecialty journal, publishing high quality articles. It gives a platform to the authors to publish their research work which can be available for everyone across the globe to read. The best thing about JCDR is that the full articles of all medical specialties are available as pdf/html for reading free of cost or without institutional subscription, which is not there for other journals. For those who have problem in writing manuscript or do statistical work, JCDR comes for their rescue.
The journal has a monthly publication and the articles are published quite fast. In time compared to other journals. The on-line first publication is also a great advantage and facility to review one's own articles before going to print. The response to any query and permission if required, is quite fast; this is quite commendable. I have a very good experience about seeking quick permission for quoting a photograph (Fig.) from a JCDR article for my chapter authored in an E book. I never thought it would be so easy. No hassles.
Reviewing articles is no less a pain staking process and requires in depth perception, knowledge about the topic for review. It requires time and concentration, yet I enjoy doing it. The JCDR website especially for the reviewers is quite user friendly. My suggestions for improving the journal is, more strict review process, so that only high quality articles are published. I find a a good number of articles in Obst. Gynae, hence, a new journal for this specialty titled JCDR-OG can be started. May be a bimonthly or quarterly publication to begin with. Only selected articles should find a place in it.
An yearly reward for the best article authored can also incentivize the authors. Though the process of finding the best article will be not be very easy. I do not know how reviewing process can be improved. If an article is being reviewed by two reviewers, then opinion of one can be communicated to the other or the final opinion of the editor can be communicated to the reviewer if requested for. This will help one’s reviewing skills.
My best wishes to Dr. Hemant Jain and all the editorial staff of JCDR for their untiring efforts to bring out this journal. I strongly recommend medical fraternity to publish their valuable research work in this esteemed journal, JCDR".

Dr. Mamta Gupta
(Ex HOD Obs &Gynae, Hindu Rao Hospital and associated NDMC Medical College, Delhi)
Aug 2018

Dr. Rajendra Kumar Ghritlaharey

"I wish to thank Dr. Hemant Jain, Editor-in-Chief Journal of Clinical and Diagnostic Research (JCDR), for asking me to write up few words.
Writing is the representation of language in a textual medium i e; into the words and sentences on paper. Quality medical manuscript writing in particular, demands not only a high-quality research, but also requires accurate and concise communication of findings and conclusions, with adherence to particular journal guidelines. In medical field whether working in teaching, private, or in corporate institution, everyone wants to excel in his / her own field and get recognised by making manuscripts publication.

Authors are the souls of any journal, and deserve much respect. To publish a journal manuscripts are needed from authors. Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards. Both ways its true "No authors-No manuscripts-No journals" and "No journals–No manuscripts–No authors". Reviewing a manuscript is also a very responsible and important task of any peer-reviewed journal and to be taken seriously. It needs knowledge on the subject, sincerity, honesty and determination. Although the process of reviewing a manuscript is a time consuming task butit is expected to give one's best remarks within the time frame of the journal.
Salient features of the JCDR: It is a biomedical, multidisciplinary (including all medical and dental specialities), e-journal, with wide scope and extensive author support. At the same time, a free text of manuscript is available in HTML and PDF format. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb 2007 of its first issue, it contained 5 articles only, and now in its recent volume published in April 2011, it contained 67 manuscripts. This e-journal is fulfilling the commitments and objectives sincerely, (as stated by Editor-in-chief in his preface to first edition) i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help. JCDR provides authors help in this regards.
Timely publication of journal: Publication of manuscripts and bringing out the issue in time is one of the positive aspects of JCDR and is possible with strong support team in terms of peer reviewers, proof reading, language check, computer operators, etc. This is one of the great reasons for authors to submit their work with JCDR. Another best part of JCDR is "Online first Publications" facilities available for the authors. This facility not only provides the prompt publications of the manuscripts but at the same time also early availability of the manuscripts for the readers.
Indexation and online availability: Indexation transforms the journal in some sense from its local ownership to the worldwide professional community and to the public.JCDR is indexed with Embase & EMbiology, Google Scholar, Index Copernicus, Chemical Abstracts Service, Journal seek Database, Indian Science Abstracts, to name few of them. Manuscriptspublished in JCDR are available on major search engines ie; google, yahoo, msn.
In the era of fast growing newer technologies, and in computer and internet friendly environment the manuscripts preparation, submission, review, revision, etc and all can be done and checked with a click from all corer of the world, at any time. Of course there is always a scope for improvement in every field and none is perfect. To progress, one needs to identify the areas of one's weakness and to strengthen them.
It is well said that "happy beginning is half done" and it fits perfectly with JCDR. It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb 2007. This had been made possible due to the efforts and the hard work put in it. The way the JCDR is improving with every new volume, with good quality original manuscripts, makes it a quality journal for readers. I must thank and congratulate Dr Hemant Jain, Editor-in-Chief JCDR and his team for their sincere efforts, dedication, and determination for making JCDR a fast growing journal.
Every one of us: authors, reviewers, editors, and publisher are responsible for enhancing the stature of the journal. I wish for a great success for JCDR."

Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
On May 11,2011

Dr. Shankar P.R.

"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
Most of the manuscripts are published within 3 to 4 months of their submission if they are found to be suitable after the review process. JCDR is published bimonthly and the accepted articles were usually published in the next issue. Recently, due to the increased volume of the submissions, the review process has become slower and it ?? Section can take from 4 to 6 months for the articles to be reviewed. The journal has an extensive author support system and it has recently introduced a paid expedited review process. The journal also mentions the average time for processing the manuscript under different submission systems - regular submission and expedited review.
Strengths of the journal: The journal has an online first facility in which the accepted manuscripts may be published on the website before being included in a regular issue of the journal. This cuts down the time between their acceptance and the publication. The journal is indexed in many databases, though not in PubMed. The editorial board should now take steps to index the journal in PubMed. The journal has a system of notifying readers through e-mail when a new issue is released. Also, the articles are available in both the HTML and the PDF formats. I especially like the new and colorful page format of the journal. Also, the access statistics of the articles are available. The prepublication and the manuscript tracking system are also helpful for the authors.
Areas for improvement: In certain cases, I felt that the peer review process of the manuscripts was not up to international standards and that it should be strengthened. Also, the number of manuscripts in an issue is high and it may be difficult for readers to go through all of them. The journal can consider tightening of the peer review process and increasing the quality standards for the acceptance of the manuscripts. I faced occasional problems with the online manuscript submission (Pre-publishing) system, which have to be addressed.
Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work."

Dr. P. Ravi Shankar
KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
On April 2011

Important Notice

Case report
Year : 2012 | Month : August | Volume : 6 | Issue : 6 | Page : 1070 - 1072

Low Grade Fibromyxoid Sarcoma Presented with Local Recurrence and an Extensive Foot Deformity

Sunil V. Jagtap, Dhiraj B Nikumbh, P.G. Chougule, Ashish O. Bohra, Swati S. Jagtap

1. Corresponding Author. 2. Department of Pathology. 3. Department of Surgery. 4. Department of Pathology. 5. Department of Physiology,Krishna Institute of Medical Sciences University and Krishna Hospital and Research Center, Karad, India.

Correspondence Address :
Dr. Sunil Vitthalrao Jagtap (MD) Associate Professor Department of Pathology Krishna Institute of Medical Sciences University, Karad, Maharashtra, India. Phone: 9960628672. E-mail:


Low Grade Fibromyxoid Sarcoma (LGFMS) is a rare neoplasm commonly affects young adults and which typically arises in the deep soft tissues of the proximal extremities. This tumour has the potential for local recurrence or distant metastasis. We are presenting here, the case of a 70-year old male who developed a large ulceroproliferative nodular mass in the dorsum of the left foot, which led to an extensive foot deformity with local recurrence. Careful consideration of light microscopy in view of its bland histopathological findings and immunohistochemical features is important to distinguish LGFMS from a number of other benign and malignant soft tissue neoplasms, for the proper management of the patient.


Low grade fibromyxoid sarcoma (LGFMS), Soft tissue tumour, Low grade myxofibrosarcoma

How to cite this article :

Sunil V. Jagtap, Dhiraj B Nikumbh, P.G. Chougule, Ashish O. Bohra, Swati S. Jagtap. LOW GRADE FIBROMYXOID SARCOMA PRESENTED WITH LOCAL RECURRENCE AND AN EXTENSIVE FOOT DEFORMITY. Journal of Clinical and Diagnostic Research [serial online] 2012 August [cited: 2018 Oct 21 ]; 6:1070-1072. Available from

Low Grade Fibromyxoid Sarcoma (LGFMS) is a distinctive variant of fibrosarcoma. LGFMS which was first described by Evans(1) in 1987, is a rare soft tissue sarcoma which exhibits bland histological features but a paradoxically aggressive behaviour by showing a high rate of local recurrence (33%) and metastasis(58%) (2).

Over the last two decades, roughly 150 cases have been documented with local recurrence, metastasis, and death (3). A predominance in males and young adult groups which were between the ages of 25-46 years was evident, as was reported by Goodlad et al (4).

The tumour most commonly arises in the deep soft tissues of the proximal and lower extremities, particularly in the thigh (1),(5).

We are reporting here a case of a 70-old year male who presented with a superficial ulceroproliferative and nodular mass, with local pain, extensive foot deformity and local recurrence. The surgically Surgically excised mass on histopathology revealed features suggestive of LGFMS.

Case Report

A 70-year-old male patient came to the surgical OPD of our hospital with the chief complaints of a non-healing wound over the dorsum of the left foot with a huge foot swelling of two and half years duration and difficulty in walking since three months. There was no history of trauma. His past history revealed the excision of the mass from the dorsum of the left foot one and half years back by a local practitioner. Since then, the mass had recurred after 6 months with nodular surface and skin ulceration, which slowly went on increasing. During the presentation to our hospital, the mass was found to have occupied the distal half of the foot. The local examination revealed a large, ulceroproliferative, nodular mass over the dorsum of the left foot, which totally measured 15x10 x9 cms, which involved the plantar aspect also. There were extensive deformities of all the toes and oedema on the distal one third of the leg and the foot. The left inguinal nodes were not palpable. The per abdominal examination revealed no abnormality. The X-ray of the chest and ultrasonogaphy of the abdomen showed no significant pathology. The X ray of the left foot revealed a soft tissue mass on the distal left foot with deformity of the bones. All the routine examinations were within normal limits. A small incisional biopsy was done, which was reported as suggestive of low grade fibromyxoid sarcoma. In view of its large size, the severe foot deformity, extensive surface ulceration and neurovascular defects, a below the knee amputation was done and the specimen was sent for histopathological examination. At present, the patient is on regular follow up. Gross Features: We received the left below the knee amputation specimen with the large foot mass. The dorsal aspect of the foot showed a large, irregular, nodular, bosselated, grey white mass which extended from the lateral to the medial aspect, which involved the dorsum and the plantar aspect of the foot and which totally measured 15×10×9 cm (Table/Fig 1). The lesion was composed of multiple, well circumscribed, nodular masses which extended all over the dorsum of the foot and those which extensively involved and deformed the dorsum of the foot. A large irregular surface ulcer was seen over the dorsum, which extended towards the great toe, which measured 5.2×4 cm. The surface of the ulcer was covered with necrotic slough. The cut surface of the mass was well circumscribed, with multiple, nodular grey white, fleshy areas with glistening surfaces (Table/Fig 2). Multiple sections of it were taken for the histopathological diagnosis.

Light microscopy: The multiple sections showed a nodular tumour with sharp demarcation beneath the skin. The skin was thinned out and at places, it was ulcerated by the underlying tumour (Table/Fig 3). The tumour was composed of moderate to low cellularity of a biphasic pattern, with alternate fibrous and myxoid areas. The tumour cells were arranged in fascicles and in swirling and whorled patterns. The individual tumour cells were bland and oval to spindle shaped, with small hyperchromatic, oval to tapering nuclei, which contained fine clumped chromatin and a pale, ill defined cytoplasm. The background matrix ranged from fibromyxoid to dense fibrous (Table/Fig 4) & (Table/Fig 5). At places, stellate cells were noted in the fibromyxoid areas (Table/Fig 6). An occasional area of necrosis with a low mitotic activity was noted. Based on these features, the tumour was diagnosed as low grade fibromyxoid sarcoma. Immunohistochemistry was performed to confirm the diagnosis. The neoplasm stained strongly for vimentin and it stained negative for other markers like CD34, CD68, SM actin and S-100.


The Stanford School of Medicine defined low grade fibromyxoid sarcoma as a cytologically bland malignant neoplasm with alternate fibrous and myxoid stroma of a low grade/ low malignant potential (6).

Low grade fibromyxoid sarcoma (LGFMS) was first described by Evans (1) as a slow growing, asymptomatic soft tissue tumour with apparently benign histological characteristics, which belied a high metastatic potential. The usual presentation of the tumour is a slow growing, painless, deep soft tissue mass that ranges from 1-18cm in greatest diameter, although most are about 8-10 cm (7).The tumour most commonly arises in the deep soft tissues of the lower extremities, particularly the thigh. The following regions can be affected in the decreasing order of frequency: The chest wall/axilla, shoulder, inguinal, buttock and the neck (5),(8).

In recent years, several new entities of LGFMS have been described, which are: [2,5] 1. Low grade myxofibrosarcoma 2. Low grade fibromyxoid sarcoma 3. Hyalinising spindle cell tumour with giant collagen rosette (HST)- Evans tumour 4. Sclerosing epitheliod fibrosarcoma Myxofibrosarcoma may show a progression to high grade sarcoma, but the remaining three types almost always remain as low grade fibrosarcoma (2),(5).

Evans (1) and Goodlad et al (4) suggested that LGFMS were paradoxically aggressive tumours. In the retrospective early series, local recurrence was noted in 68%, metastasis in 41% and death from the disease in 18% of the tumours. So, Evans HL (9), in 1993, labeled LGFMS as a distinctive soft tissue sarcoma with the most common affected location as the thigh, with predominance of local recurrence and distant metastasis to the lung according to his report on 12 cases.

We are reporting here, a case of a 70-year old male who presented with LGFMS as multiple local recurrence, foot deformities, surface ulcerations and pressure effects. Clinically, an extensive foot deformity was noted, which led to an inability to walk and to do the routine daily activities. In view of the above features, a below the knee amputation was done and the patient was advised regular follow up.

Regarding the differential diagnosis of LGFMS, it involves numerous benign and malignant soft tissue lesions which are characterized by fibrous and myxoid stroma, such as desmoids fibromatosis, perineuroma, myxoid neurofibroma, nodular fasciitis, low grade myxofibrosarcoma, myxoid liposarcoma and malignant peripheral nerve sheath tumour (6). These lesions should be differentiated because their clinical behaviour and prognosis differs.

Desmoids fibromatosis and low grade myxofibrosarcoma are the most important differential diagnoses which should be discussed, as per the Stanford School of Medicine (6).

In extraintestinal desmoids fibromatosis–sweeping bundles of cells are seen instead of the whorled or swirling patterns. The nuclei are vesicular, with no rosettes. Frequent slit like vessels are noted.

Another differential diagnosis is low grade myxofibrosarcoma which is characterized by a lack of fibrous and myxoid alternate areas, with the presence of pleomorphic nuclei and an abnormal mitotic activity. These lesions are often subcutaneous and cellular. These features are lacking in LGFMS (6).

The chromosomal translocation, t (7;16) (q33;p11) is identified in up to 96% of the LGFMS cases. This genetic abnormality is not present in other myxoid or fibrous neoplasms (6).


Low grade fibromyxoid sarcoma is a rare entity with cytologically bland, malignant neoplasm and an aggressive nature. So, LGFMS should be considered in the differential diagnosis of spindle cell neoplasms while the histopathology of soft tissue tumours are studied. A regular follow up for local recurrence as paradoxically aggressive behaviour of tumour will be helpful for patient care. We are presenting this case of LGFMS due to its unusual and unique presentation as local recurrence and an extensive foot deformity.


Evans HL. Low grade fibromyxoid sarcoma: A report of two metastasizing neoplasms which had a deceptively benign appearance. Am J Clin Path. 1987;88(5): 615-19.
Hansen T, Katenkamp k, Broadhum M, Katenkamp D. Low grade fibrosarcoma: A report on 39 not otherwise specified cases and comparison with the defined, low grade fibrosarcoma types. Histopathology, 2006; 49:152-60.
Wn X, Petronic V, Torode IP, Chow CW. Low grade fibromyxoid sarcoma: problems in the diagnosis and management of malignant tumours with a bland histopathological appearance. Pathology. 2009; 41:155-60.
Goodland JR, Mentez T, Fletur CD. Low grade fibromyxoid sarcoma: a clinicopathological analysis of 11 new cases in support of a distinct entity. Histopathology, 1995;26:229-37.
Weiss SW, Goldblum JR. Fibrosarcoma. In: Weiss SW, Goldblum JR (editors) Enzinger and Weiss’s Soft Tissue Tumours, ed. 4. New York: Mosby Inc, 2001;409-25.
Kempson RL, Rouse RV. Low grade fibromyxoid sarcoma. Stanford School of Medicine. (cited on 2011Sep 2). Available from http:// sarcoma/printable.
Lee WJ, Pork CO, Yoon SH, ChuYC.. Primary paravertebral low grade fibromyxoid sarcoma. J Korean Neuro Surg Soc, 2010;48:461-64.
Vernon SE, Bejaruno PA. Low grade fibromyxoid sarcoma. A brief review. Arch Pathol Lab Med, 2006; 130:1358-60.
Evans HL. Low grade fibromyxoid sarcoma. A report of 12 cases. Am J Surg Pathol, 1993;17(6): 595-600.

DOI and Others

ID: JCDR/2012/4008:2337

Date of Submission: Nov 12, 2011
Date of Peer Review: Jan 11, 2012
Date of Acceptance: Jan 19, 2012
Date of Publishing: Aug 10, 2012


JCDR is now Monthly and more widely Indexed .
  • Emerging Sources Citation Index (Web of Science, thomsonreuters)
  • Index Copernicus ICV 2016: 132.37
  • Academic Search Complete Database
  • Directory of Open Access Journals (DOAJ)
  • EBSCOhost
  • Embase & EMbiology
  • Google Scholar
  • HINARI Access to Research in Health Programme
  • Indian Science Abstracts (ISA)
  • Journal seek Database
  • Google
  • Popline (reproductive health literature)