Panhypopituitarism without Thrombosis due to Primary Antiphospholipid SyndromeCorrespondence Address :
Dr. Subodh Kumar Mahto,
Senior Resident, Department of Medicine, OPD Block, PGIMER, Dr. RML Hospital, New Delhi-110001, India.
Hypopituitarism is a clinical syndrome in which pituitary hormones deficiency is seen in many conditions. Antiphospholipid Syndrome (APS) is an autoimmune disease characterised by antiphospholipid antibodies, commonly manifests as venous or arterial thrombosis with recurrent foetal loss. We here by report a case of 40-year-old female who presented with bilateral swelling of lower limbs with exertional breathlessness along with feeling of cold extremities, easy fatigability, lethargy and decreased appetite for six months which turned out to be hypopituitarism with APS. Hormone replacement was started and she experienced a good clinical improvement.
Autoimmune, Hormone replacement, Hypopituitarism
Pulin Kumar Gupta, Subodh Kumar Mahto, Arjun Malasandra Balakrishna, Parikha Rampal, Narendra Kumar Sharma. PANHYPOPITUITARISM WITHOUT THROMBOSIS DUE TO PRIMARY ANTIPHOSPHOLIPID SYNDROME. Journal of Clinical and Diagnostic Research [serial online] 2019 February [cited: 2019 Feb 19 ]; 13:OD10-OD11. Available from
Date of Submission: Oct 31, 2018
Date of Peer Review: Nov 20, 2018
Date of Acceptance: Dec 11, 2018
Date of Publishing: Feb 01, 2019
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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