A Rare Case of Paranasal Sinus Schwannoma with Intracranial ExtensionCorrespondence Address :
Dr. Asha Sharad Shenoy,
301, Arihant, 613-B ,15th Road, Khar, Mumbai-400052, Maharashtra, India.
Paranasal sinus schwannomas are uncommon and account for less than 4% of head and neck schwannomas. Intracranial extension and aggressive behaviour are very rarely observed in these tumours leading to misdiagnosis of a malignant neoplasm. Here, we report a case of a 35-year-old male with complaint of proptosis. MRI showed a tumour in the region of ethmoid sinus with expansion into anterior cranial fossa. Microscopy revealed a biphasic tumour with compact and loose areas. Tumour was composed of spindle cells with wavy nuclei, showing focal palisading and a strong immunoreactivity for S100. MIB-1 index was around 1%. A diagnosis of Schwannoma was favoured based on histology and immunohistochemistry.
S100, Antoni A, Antoni B, Middle cranial fossa
Mihir Mohan Vaidya, Asha Sharad Shenoy, Naina Atul Goel. A RARE CASE OF PARANASAL SINUS SCHWANNOMA WITH INTRACRANIAL EXTENSION. Journal of Clinical and Diagnostic Research [serial online] 2019 March [cited: 2019 Mar 26 ]; 13:ED08-ED09. Available from
Date of Submission: Nov 14, 2018
Date of Peer Review: Dec 12, 2018
Date of Acceptance: Jan 17, 2019
Date of Publishing: Mar 01, 2019
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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