A Case of Blistering Eruptions in Systemic Lupus ErythematosusCorrespondence Address :
Dr. Sarojini Raman,
Department of Pathology, KIMS, Campus-5, Kiit Campus, BBSR, Bhubaneswar-751024, Odisha, India.
Cutaneous vesiculobullous lesions have a wide aetiological spectrum ranging from autoimmunity to medications and infections. Systemic Lupus Erythematosus (SLE) is one of most frequent autoimmune diseases with its cutaneous form being very uncommonly encountered. We report a case of Bullous Systemic Lupus Erythematosus (BSLE). Patient presented with fever, arthalgia and widespread blistering eruptions on face, neck and upper chest wall. Skin biopsy revealed subepidermal bulla and Direct Immunofluorescence (DIF) showed deposition of IgG, IgA, IgM, C3, C1q at the dermoepidermal junction. On treatment lesions healed rapidly. So proper clinical acumina is essential for diagnosis and management of such cases excluding the differentials.
Autoimmunity, Direct, Fluorescent antibody technique, Skin
Sarojini Raman, Abhimanyu Grover, Prasant Padhan, Urmila Senapati. A CASE OF BLISTERING ERUPTIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS. Journal of Clinical and Diagnostic Research [serial online] 2019 September [cited: 2019 Sep 16 ]; 13:ED04-ED05. Available from
Date of Submission: Jun 28, 2019
Date of Peer Review: Jul 30, 2019
Date of Acceptance: Aug 16, 2019
Date of Publishing: Sep 01, 2019
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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