Effect of Magnesium Sulphate as an Adjuvant to Bupivacaine in Interscalene Brachial Plexus Block for Postoperative AnalgesiaCorrespondence Address :
Dr. Sofia Jaswal,
House No. 421, Ground Floor, Omaxe City, Phase 2, New Chandigarh-140901, India.
Introduction: Ultrasound guided interscalene block is used for the upper limb surgeries. Various adjuvants have been used for prolonging the local anaesthetic action, without increasing the drug dosage.
Aim: To evaluate the effect of magnesium sulphate (MgSO4) as an adjuvant to bupivacaine on onset and duration of interscalene block, haemodynamic parameters, and requirement of postoperative analgesics.
Materials and Methods: A total of 60 ASA I and II patients of age group 20-60 years were scheduled for shoulder and arm surgeries. The patients received 20 mL of 0.5% bupivacaine with 0.5 mL of MgSO4 (50%) in Group I and 20 mL of bupivacaine with 0.5 mL saline in Group II for ultrasound guided interscalene block. Onset and duration of sensory and motor block was noted. VAS score, time to first rescue analgesic and total analgesic used in 24 hour were recorded.
Results: The demographic profile was comparable (p>0.05). The mean onset of sensory blockade and motor blockade was comparable in both the groups (p>0.05). The duration of sensory blockade was significantly prolonged in Group I (759.93 min) as compared to Group II (568.37 min) (p<0.001). The duration of motor blockade was 350.17 minutes in group I and 300.27 minutes in Group II and the difference was significant (p<0.001). The VAS scores were significantly lower in Group I as compared to Group II (p<0.05). The time to first rescue analgesic and total analgesic used in 24 hours were significantly less in group I (p<0.001).
Conclusion: MgSO4 as an adjuvant to ultrasound guided interscalene block significantly improves the quality and duration of the block.
Motor block, Sensory block, Ultrasound guided, Upper limb surgery
Aparna Sharma, Sofia Jaswal, Vikas Jaswal, Jyoti Pathania. EFFECT OF MAGNESIUM SULPHATE AS AN ADJUVANT TO BUPIVACAINE IN INTERSCALENE BRACHIAL PLEXUS BLOCK FOR POSTOPERATIVE ANALGESIA. Journal of Clinical and Diagnostic Research [serial online] 2019 October [cited: 2019 Oct 16 ]; 13:UC01-UC04. Available from
Date of Submission: May 14, 2019
Date of Peer Review: Jun 03, 2019
Date of Acceptance: Sep 10, 2019
Date of Publishing: Oct 01, 2019
• Financial or Other Competing Interests: No
• Was Ethics Committee Approval obtained for this study? Yes
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. NA
PLAGIARISM CHECKING METHODS: [Jain H et al.]
• Plagiarism X-checker: May 18, 2019
• Manual Googling: Sep 07, 2019
• iThenticate Software: Sep 17, 2019 (18%)
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