
Invasive Non-typhoidal Salmonella Sepsis in Top-up Fed Five-Month-Old Infant: Case Report
Correspondence Address :Dr. Vivek Hada,
Assistant Professor, Department of Microbiology, All India Institute of Medical
Sciences, Kunraghat, Gorakhpur-273008, Uttar Pradesh, India.
E-mail: vivekhada7285@gmail.com
Non-typhoidal Salmonella (NTS) are generally associated with self-limiting gastrointestinal disease, often acquired through the ingestion of contaminated food and it seldom requires antimicrobial therapy for treatment. Extra-intestinal manifestations could be localised infection leading to septic arthritis, osteomyelitis. In complicated invasive disease, there could be bronchopneumonia with or without bacteraemia leading to mortality. Invasive NTS infections are infrequently reported in India. The S. Typhimurium is one of the common serovars associated with invasive disease and its virulence factors are responsible for causing the disease. S. enteridies, S. Dublin are the other serovars which are commonly responsible for invasive NTS infection. It is difficult to diagnose invasive disease without appropriate bacteriological culture based method. With emergence to resistance to antimicrobials the treatment of this condition is also becoming challenging. In this case report, a five-month-old infant presented with cough fever, stuffed nose dyspnoea and was diagnosed as bronchopneumonia. Mechanical ventilation was required for five days along with admission to intensive care unit. Invasive NTS infection was diagnosed using automated blood culture and the child responded to intravenous antimicrobial chemotherapy
Blood culture, Bronchopneumonia, Food borne infection, Salmonella Typhimurium
DOI: 10.7860/JCDR/2021/47924.14539
Date of Submission: Dec 17, 2020
Date of Peer Review: Jan 05, 2021
Date of Acceptance: Jan 13, 2021
Date of Publishing: Feb 01, 2021
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes (Parental consent)
• For any images presented appropriate consent has been obtained from the subjects. Yes (Parental consent)
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Dec 24, 2020
• Manual Googling: Jan 10, 2021
• iThenticate Software: Jan 20, 2021 (10%)
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