
Orofacial Findings and Dental Management of Noonan Syndrome: A Case Report
Correspondence Address :Razeem Khalid Alhassoun,
Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
E-mail: razeemkhalid@gmail.com
Noonan Syndrome (NS) is an autosomal dominant condition caused by mutations in multiple genes in the RAS-MAP (MitogenActivated Protein) Kinase pathway. It is typically characterised by short stature, broad webbed neck, abnormal chest shape, congenital heart defects and developmental delay. Oral manifestations include high arched palate, micrognathia, malocclusion, impacted teeth and jaw bones. Presented here is a case of NS in a 26-year-old female, reported to the dental clinic in College of Dentistry, Princess Nourah Bint Abdulrahman University. The cranio-dentofacial features of this syndrome can be diagnosed by the dentist and these features can be unrecognised by the physician. The dentofacial features of the patient included a broad forehead, down slanting palpebral fissure, flat base of the nose and low junction of the ears, prominent nasolabial folds, Class III molar malocclusion, edge-to-edge bite, high arched palate, and congenitally missing teeth. The present patient was first diagnosed by a dental professional and hence, this case report aims to present this syndrome from a dental viewpoint. The treatment plan was to improve her oral hygiene, retain the deciduous tooth and space maintainer in the congenitally missing tooth to preserve space for the future prosthodontic treatment.
Craniofacial abnormalities, Oral manifestations, Unerupted teeth
DOI: 10.7860/JCDR/2021/43842.14436
Date of Submission: Feb 05, 2020
Date of Peer Review: Mar 23, 2020
Date of Acceptance: Dec 01, 2020
Date of Publishing: Jan 01, 2021
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Feb 06, 2020
• Manual Googling: Oct 24, 2020
• iThenticate Software: Dec 21, 2020 (14%)
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