Biosynthesis and Characterisation of Ellagic Acid Coupled Silver Nanoparticles- An In-vitro StudyCorrespondence Address :
Associate Professor, Department of Conservative Dentistry and Endodontics,
Vivekanandha Dental College for Women, Elayampalayam, Tiruchengode,
Namakkal, Tamil Nadu, India.
Email Id: firstname.lastname@example.org
Introduction: Nanomedicine dominated the world of therapeutics and diagnostics. Horizons are extending daily to identify a piece of the puzzle that helps us produce eco-friendly and cost-effective nanoparticles. In this, authors tried to synthesise a novel Silver Nanoparticle Coated with Ellagic Acid (EA-AgNPs) obtained from pomegranate using a simple method and explore its characterisation precisely.
Aim: To biosynthesise and assess the characterisation of Ellagic Acid coupled Silver Nanoparticles.
Materials and Methods: The study assessed the portrayal of EA-AgNPs were evaluated using various analytical techniques. Firstly, to analyse: the size of the EA-AgNPs using Ultraviolet (UV)-Visible Spectrometer; Secondly to determine the hydrodynamic size and its dispersity using Dynamic Light Scattering (DLS) and Zeta potential; thirdly to quantify the average size of EA-AgNPs by using Scanning Electron microscope (SEM); and lastly to identify the functional groups by using Fourier Transform Infrared Spectroscopy (FTIR) method. Descriptive statistics were used to analyse the results.
Results: Brownish colour change and shift of peak wavelength from 430 to 423 nm using UV-Visible Spectrometer analysis confirmed the formation and stability of EA-AgNPs. The DLS analysis revealed that EA-AgNPs were in nanosize (129.7 nm) with less aggregated polydispersity index (0.483). The Zeta potential confirmed that this newly synthesised nanoparticle was negatively charged -0.268mv. The SEM determination confirmed the formation of spherical-shaped nanoparticles with sizes ranging from 84.34-98.80 nm. The FTIR revealed EA-AgNPs exhibited different functional groups, which help to prevent particle aggregation.
Conclusion: In this work, the novel EA-AgNPs exhibited the apt characterisation needed for an effective and cost-efficient nanoparticle that could be effectively tapped in various fields of nanodentistry.
Analytical technique, Capping agents, Ellagic acid, Green chemistry, Nanomedicine, Reducing agents
Date of Submission: Sep 01, 2021
Date of Peer Review: Sep 23, 2021
Date of Acceptance: Oct 01, 2021
Date of Publishing: Nov 01, 2021
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? NA
• Was informed consent obtained from the subjects involved in the study? NA
• For any images presented appropriate consent has been obtained from the subjects. NA
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ETYMOLOGY: Author Origin
- Emerging Sources Citation Index (Web of Science, thomsonreuters)
- Index Copernicus ICV 2017: 134.54
- Academic Search Complete Database
- Directory of Open Access Journals (DOAJ)
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Popline (reproductive health literature)