Protective Effect of Yerba Mate on Rats Fed on High Cholesterol Diet- An Experimental StudyCorrespondence Address :
Fahmida Khatoon Zahid Balouch,
Azizyah Hail, Saudi Arabia.
Introduction: Yerba mate tea, a concoction made from the leaf extracts of the tree Ilex paraguariensis, is a broadly consumed non alcoholic beverage in Latin America which is gaining rapid introduction into the world market.
Aim: To explore the influence of Yerba Mate (Ilex paraguariensis) powder and beverage on induced hypercholesterolemic rats.
Materials and Methods: The experiment was carried out for a duration of one year from February 2020 to January 2021 at University of Ha'il, Ha'il, Saudi Arabia. on 48 male Albino rats divided into six subgroups; Control (-) group: group fed a basal diet. Rats in the other five groups fed on basal diet containing 2% cholesterol + 0.25% bile salts for two weeks to induce hypercholesterolemia. Then those rats were subdivided into: control (+) group: group that remained hypercholesterolemic. Yerba Mate Powdered (YMP) 15% group: fed on hypercholesterolemic diet + YMP15%; YMP 10% Group: fed on hypercholesterolemic diet + YMP10%; Yerba Mate Beverage (YMB) 15% group: fed on a hypercholesterolemic diet + YMB 15%; and YMB 10% group: fed on a hypercholesterolemic diet + YMB 10%.
Results: It was found that, with increasing the amount of Yerba Mate powder or beverage, the total cholesterol, triglycerides, Low Density Lipoprotein-Cholesterol (LDL-C), Aspartate Transaminase (ALT), Alanine Transaminase (ALT), urea nitrogen and glucose levels decreased significantly (p<0.05) and the best result belonged to the group of rats that fed on Yerba Mate 15% powder.
Conclusion: From the obtained results it can be concluded that, supplementation with high percentage of Yerba Mate powder (15%) exerts a positive impact on the lipid profile and other biochemical parameters in hypercholesterolemic rats.
Biochemical parameters, Hypercholesterolemia, Ilex paraguariensis, Lipids
Date of Submission: Nov 27, 2020
Date of Peer Review: Dec 31, 2020
Date of Acceptance: May 01, 2021
Date of Publishing: Oct 01, 2021
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? NA
• Was informed consent obtained from the subjects involved in the study? NA
• For any images presented appropriate consent has been obtained from the subjects. NA
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ETYMOLOGY: Author Origin
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