Plasma Exchange as a Rescue Therapy for Acute Liver Failure
Correspondence Address :
Dr. Nupur B Patel,
Senior Resident, Department of Critical Care Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
E-mail: nupurbpatel@yahoo.co.in
Acute Liver Failure (ALF) is a life-threatening condition and often necessitates Liver Transplantation (LT). However, LT is not available to most patients in developing countries due to resource constraints. A 30-year-old female presented to us with ALF and fulfilled criteria for LT. The aetiology of ALF could not be diagnosed in her. Due to the lack of LT facilities, she was offered plasma exchange as a therapeutic option, which resulted in improvement in sensorium and Liver Function Tests (LFT) {bilirubin, International Normalised Ratio (INR), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT)} over a period of two weeks. She was discharged and was doing well during follow-up. Plasma exchange is a less studied but potential treatment option for ALF when LT is not feasible.
Gastroenterology, Hepatitis, Liver function tests
10.7860/JCDR/2021/49865.15371
Date of Submission: Apr 13,2021
Date of Peer Review: Jul 16, 2021
Date of Acceptance: Aug 12, 2021
Date of Publishing: Sep 01, 2021
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Apr 14, 2021
• Manual Googling: Jul 29, 2021
• iThenticate Software: Aug 18, 2021 (5%)
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