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Aug 2018




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Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
E-mail: drrajendrak1@rediffmail.com
On May 11,2011




Dr. Shankar P.R.

"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
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KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
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On April 2011
Anuradha

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Dr. Anuradha
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On Jan 2020

Important Notice

Original article / research
Year : 2022 | Month : October | Volume : 16 | Issue : 10 | Page : FC06 - FC09 Full Version

Drug Storage and Self-medication Practices in Kashmir, India: A Cross-sectional Study


Published: October 1, 2022 | DOI: https://doi.org/10.7860/JCDR/2022/56886.17091
Rehana Tabassum, Syed Sajad Hussain, Sajad Hussain Arif

1. Professor, Department of Pharmacology, Government Medical College, Srinagar, Jammu and Kashmir, India. 2. Assistant Professor, Department of Pharmacology, Government Medical College, Srinagar, Jammu and Kashmir, India. 3. Associate Professor, Department of Neurosurgery, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

Correspondence Address :
Dr. Syed Sajad Hussain,
Shalabagh, Zadibal, Srinagar-190011, Jammu and Kashmir, India.
E-mail: sajadsafvi@gmail.com

Abstract

Introduction: Among the various potential health risks, selfmedication and inappropriate storage of medicines at home are found to be very important. Inappropriate storage conditions and irrational use of medication without medical consultation may result in serious health problems. Worldwide there has been an increase in the self-medication rate, which can lead to waste of resources and serious adverse reactions.

Aim: To assess the practice of self-medication and household storage of medicines amongst the study population.

Materials and Methods: This was a cross-sectional and questionnaire based study conducted in the southern district of Kashmir, India from 1st September 2021 to 28th February 2022. A total of 471 households were included and interviewed to determine the practice of home storage of medicines and selfmedication pattern. Quantitative data was presented as means and standard deviation (mean±SD) and qualitative data as frequency and 95% Confidence Interval (CI).

Results: Almost three quarters of the households were having monthly income of less than 20,000 INR whereas 219 (46.50%) of them were illiterate. Proton pump inhibitors, minerals and vitamins, antibiotics and analgesics were the most common medicines stored at home. Drawer was the most common place used for storage of medicines whereas the refrigerator was used in less than 1% of cases for the same. Solid dosage forms were mostly used by the householders and the injectables were least used for household storage purposes.

Conclusion: The study revealed that the studied householders stored large amount of medicines in homes, often under inappropriate storage conditions. There is a need for better public knowledge and information about the risks of reuse of prescribed medications.

Keywords

Households, Medicine prescription, Utilisation pattern

In self-medication practices, individuals use medicinal products to treat self-recognised diseases or symptoms. It also involves the intermittent or continuous use of medication which were prescribed by physician for chronic or recurrent disease or symptoms (1). Selfmedication has turned out to be a global concern involving both developed as well as developing countries (2). According to one estimate, about 60-80% of health problems are treated by selfmedication (3). In recent years, medicine consumption pattern has been changed, resulting in larger purchasing volumes of medicine. Hence the excessive amount of these medicines are being stored at home (4). Accumulation of medicine may lead to increased costs and can prove harmful to both patients as well as to other family members (5). Among the various factors that influence the practice of self-medication, increasing disease burden especially in developing countries, desire for quick recovery from illness and the acceptance of self-medication among communities are the commonest ones (6).

One of the reasons for irrational drug use can be related to the easy availability of drugs at home. The undesired storage of these drugs may affect the drug stability which increases the risk of unwanted effects as well as leads to ineffective drug therapy among its users (7),(8). Many studies have been carried out previously that have identified a relationship between medicine storage and self-medication practices (9),(10). In a study carried out by Kiyingi KS and Lauwo JAK, it was found that the presence of medicines in households is one of the risk factors for encouraging inappropriate drug use such as the use of the antimicrobial drugs in illnesses when they are not indicated mainly due to the ease of access (10). This includes medications stored intentionally while they are being used or medications that are incompletely used. Storing medicines at home have been found to increase the risk of self-medication and some authors have reported a high frequency of exchange of self-medication between family members (11). The much needed information on the access and use of medicine can be obtained from pattern, extent, source and storage conditions of medicines kept at household level. Studies on household use and storage of medicines have been conducted world over. Among the studies conducted, several studies revealed that significant proportions of households stored medicines whereas in some cases, all of them were keeping medicines at home (12),(13). Only a couple of studies have been conducted to enlighten the facts about the drug storage in Kashmir (14),(15). So the current study was carried out to enhance the knowledge regarding the practice of selfmedication and household storage pattern of various medicines in the Kashmir province of Union territory of Jammu and Kashmir, India.

Material and Methods

This was a cross-sectional and questionnaire based study that was undertaken in the southern district of Kashmir, India from 1st September 2021 till 28th February 2022. Chief Medical Officer of the Anantnag district was contacted to obtain formal permission to conduct the study and householders were informed in advance about the study to ensure their agreement to participate in the study. Selected households were visited and the data collection supervisors explained the objectives of the study.

Inclusion criteria: Heads of households were asked to consent for their home to be included in the study and for them to participate in filling the questionnaires.

Exclusion criteria: Only respondents with any known emotional, psychiatric, and intellectual disturbances were excluded because these conditions could affect the reliability of their response.

A sample of 471 householders were recruited by stratifying the local regions of the district (north, south, east, west and central) into different sections to cover families of different socio-economic status. Householders from each section were selected through a systematic, random sampling technique to cover all parts of the Anantnag district. The requisite sample size was achieved based on the previous study carried out and the Department of Social and Preventive Medicine provided the statistical assistance for the study (16). Each household was given a code and considered as a unit. If a householder was not willing to participate, the next household in the sampling frame was taken until the sample size was reached (n=471).

Procedure

An instrument composed of a structured interviewer-administered proforma was used for data collection [Proforma/Questionnaire]. It was developed by adapting tools used in previous studies and guidelines (16),(17) and was validated by subject experts. Householders responded to the instrument which collected data about their demographic characteristics including education status of head of family, their occupation and monthly income. During the interview, medication storage locations were directly inspected and all the medications found in the household were recorded. The medicine name, dosage form, source of the medicine, reason for storage, expiry date and storage place were taken into consideration. The reason for drug storage was not highlighted in final data as no specific reason was given by the respondents for the same and all the stored medicines were within the expiry date.

Statisctial Analysis

The data was reviewed, organised, tabulated and analysed using Microsoft Excel, 2010 version. Quantitative data was presented as means and standard deviation (mean±SD) and qualitative data as frequency and 95% CI.

Results

Out of the total participants, majority of them 219 (46.50%) were illiterate and 90 (19.11%) could only read and write. Although 69 (14.65%) had completed their primary education and 66 (14.01%) had completed their secondary education and only 27 (5.73%) had completed their studies at college level. When the nature of occupation of the heads of householders was considered, a good number of them were labourers 102 (21.66%), followed by businessmen 81 (17.19%), drivers and farmers 72 (15.29%). Majority of households 207 (43.95%) had the monthly income of less than 10,000 INR, followed by those which had monthly less than 10,000- 20,000 INR, 141(29.94%). Only 3 (0.64%) households had monthly income of 50,000-60,000 rupees (Table/Fig 1).

All the households reported that they kept medicines at home. Total numbers of medicines stored by the studied population were 1674, as most of the households stored more than one medicine. Most common place to store the medicine was found to be drawer 894 (53.41%), followed by cupboard 366 (21.86%). Only 12 (0.72%) of householders used to store their medicines in refrigerator. The results of the present study showed that tablets were the most common drug formulation used 978 (58.42%), which was followed by capsules 318 (19%) and oral liquids 267 (15.95%). Injectables were used only in 15 (0.90%) instances. Proton pump inhibitors were the most common reported therapeutic category of drugs used by the householders 228 (13.62%). Minerals and vitamins were the next therapeutic category of drugs commonly used 186 (11.11%). Antibiotics and analgesics were equally used by 165 (9.86%) of the total householders questioned during the study (Table/Fig 2).

Discussion

This pragmatic study was conducted in rural areas in the southern part of Kashmir, India, revealed the socio-demographic profile of the participating householders and revealed the various facts about the home storage of medication. Majority of the heads of the households were illiterate 219 (46.50%) and only 27 (5.73%) of them were having the college level education. This was in contrast to a similar study carried out in Kashmiri population where 94% of the studied population was found to be literate (14). This can be justified by the fact that the said survey was conducted in urban population where the majority population has access to educational institutes and the literacy levels are generally very high compared to rural areas where the current study was conducted. Majority of the studied cases 207 (43.95%) were having the monthly income of less than 10.000 rupees. These results were similar to the study carried out in Maharashtra, where the majority of households had monthly income of less than 15,000 INR (18). This can be justified by the fact that since the study was conducted in the rural areas where heads of the household used to indulge in the low wage work at the earliest of their age and paying least attention for their academic carriers.

The present study revealed that nearly three-fourth of households stored medicines either in the drawer or cupboard whereas less than 1% of them used the refrigerator for storage purpose. The correct storage place of the medicine depends on the nature of the medicine itself. Most of the drugs can be stored at desired room temperature whereas few medicines such as antibiotic suspensions after preparation must be kept cool but not frozen. These results were similar to the study conducted in Qatar, where most medicines were kept in the bedroom drawer (19). The adequacy of household storage is influenced by the location of the medicine. One of the risk factors for the occurrence of accidental poisoning in children and suicide attempts have been found to be storing drugs at places which are easily accessible (20),(21). Criteria for adequate home storage of medications given by some regulatory agencies are to store medicines out of reach of children and to be protected from heat, humidity, light, and dust (22),(23).

Tablets were the formulations most commonly used for self-medication 978 (58.42%). However, it should be emphasised that tablets might be the most frequently used dosage form in self-medication simply because most medicines for self-medication come in tablet form. This was followed by capsules formulation which was used in 318 (19%) cases. Solid dosage formulations (tablets and capsules) are commonly used drug formulations because of their ease of administration and acceptability in the community (24). Similar results were reported by a study carried by Martins RR et al., (25).

The results of the current study showed that stored medicines belonged mostly to four categories: proton pump inhibitors, minerals and vitamins, analgesics and antibiotics. Almost similar results were reported in a study carried out on Iranian households where analgesics, adult cold remedies and antibiotics were the three most commonly used therapeutic drug categories (26). The respiratory medicines (16.8%), Central Nervous System (CNS) agents (16.4%) and antibiotics (14.3%), were found to be most commonly reused medicines in a study carried out by Abou-Auda HS (27).

The present study results were in contrast to the British study, 28.0% cardiovascular medicines, 19.1% CNS agents, 14.8% respiratory agents, 11.4% gastrointestinal agents and only 4.0% antibiotics were returned to pharmacies (28). One of the risk factors for encouraging inappropriate drug use such as using the antimicrobial drugs in illnesses when they are not indicated is the ease of access to them. This inappropriate use of antimicrobials can potentially cause adverse drug reactions and lead to development of antimicrobial resistance, which is considered as the most serious challenge throughout the world (29). Similar studies have been tabulated in (Table/Fig 3) (8),(19),(26).

Limitation(s)

Although the present study was a community based and was not based on a specific target group however an absence of a standard definition of self-medication and the study design which did not include a comparison group means the results should be interpreted with caution and many more studies are needed to authenticate the results.

Conclusion

The studied householders stored large amount of medicines in homes. Most common place to store the medicine was found to be drawer (53.41%) and tablets (58.42%) were the most common drug formulation used. Since the study was carried out in rural population, most of the households were having low education level and belonged to low socio-economic sectors. Most often the stored medicines were not stored under proper storing conditions which can lead to unauthorised use of these medicines by the family members. Since large amount of medicines belonging to various drug classes (Analgesic, Multivitamins, Antibiotics and Antihypertensive) were stored by the households, the prescribers have to take into account that their patients are likely to keep several prescription medicines in their homes. These patients are potential providers of these medicines to their relatives and friends which can lead to unsafe self-medication. There is a need for better public knowledge and information about the risks of reuse of prescription medications.

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DOI and Others

DOI: 10.7860/JCDR/2022/56886.17091

Date of Submission: Apr 05, 2022
Date of Peer Review: May 16, 2022
Date of Acceptance: Aug 25, 2022
Date of Publishing: Oct 01, 2022

AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? No
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. NA

PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Apr 13, 2022
• Manual Googling: Aug 22, 2022
• iThenticate Software: Aug 24, 2022 (25%)

ETYMOLOGY: Author Origin

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