Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Dr Mohan Z Mani

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Department of Dermatolgy,
Believers Church Medical College,
Thiruvalla, Kerala
On Sep 2018




Prof. Somashekhar Nimbalkar

"Over the last few years, we have published our research regularly in Journal of Clinical and Diagnostic Research. Having published in more than 20 high impact journals over the last five years including several high impact ones and reviewing articles for even more journals across my fields of interest, we value our published work in JCDR for their high standards in publishing scientific articles. The ease of submission, the rapid reviews in under a month, the high quality of their reviewers and keen attention to the final process of proofs and publication, ensure that there are no mistakes in the final article. We have been asked clarifications on several occasions and have been happy to provide them and it exemplifies the commitment to quality of the team at JCDR."



Prof. Somashekhar Nimbalkar
Head, Department of Pediatrics, Pramukhswami Medical College, Karamsad
Chairman, Research Group, Charutar Arogya Mandal, Karamsad
National Joint Coordinator - Advanced IAP NNF NRP Program
Ex-Member, Governing Body, National Neonatology Forum, New Delhi
Ex-President - National Neonatology Forum Gujarat State Chapter
Department of Pediatrics, Pramukhswami Medical College, Karamsad, Anand, Gujarat.
On Sep 2018




Dr. Kalyani R

"Journal of Clinical and Diagnostic Research is at present a well-known Indian originated scientific journal which started with a humble beginning. I have been associated with this journal since many years. I appreciate the Editor, Dr. Hemant Jain, for his constant effort in bringing up this journal to the present status right from the scratch. The journal is multidisciplinary. It encourages in publishing the scientific articles from postgraduates and also the beginners who start their career. At the same time the journal also caters for the high quality articles from specialty and super-specialty researchers. Hence it provides a platform for the scientist and researchers to publish. The other aspect of it is, the readers get the information regarding the most recent developments in science which can be used for teaching, research, treating patients and to some extent take preventive measures against certain diseases. The journal is contributing immensely to the society at national and international level."



Dr Kalyani R
Professor and Head
Department of Pathology
Sri Devaraj Urs Medical College
Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka
On Sep 2018




Dr. Saumya Navit

"As a peer-reviewed journal, the Journal of Clinical and Diagnostic Research provides an opportunity to researchers, scientists and budding professionals to explore the developments in the field of medicine and dentistry and their varied specialities, thus extending our view on biological diversities of living species in relation to medicine.
‘Knowledge is treasure of a wise man.’ The free access of this journal provides an immense scope of learning for the both the old and the young in field of medicine and dentistry as well. The multidisciplinary nature of the journal makes it a better platform to absorb all that is being researched and developed. The publication process is systematic and professional. Online submission, publication and peer reviewing makes it a user-friendly journal.
As an experienced dentist and an academician, I proudly recommend this journal to the dental fraternity as a good quality open access platform for rapid communication of their cutting-edge research progress and discovery.
I wish JCDR a great success and I hope that journal will soar higher with the passing time."



Dr Saumya Navit
Professor and Head
Department of Pediatric Dentistry
Saraswati Dental College
Lucknow
On Sep 2018




Dr. Arunava Biswas

"My sincere attachment with JCDR as an author as well as reviewer is a learning experience . Their systematic approach in publication of article in various categories is really praiseworthy.
Their prompt and timely response to review's query and the manner in which they have set the reviewing process helps in extracting the best possible scientific writings for publication.
It's a honour and pride to be a part of the JCDR team. My very best wishes to JCDR and hope it will sparkle up above the sky as a high indexed journal in near future."



Dr. Arunava Biswas
MD, DM (Clinical Pharmacology)
Assistant Professor
Department of Pharmacology
Calcutta National Medical College & Hospital , Kolkata




Dr. C.S. Ramesh Babu
" Journal of Clinical and Diagnostic Research (JCDR) is a multi-specialty medical and dental journal publishing high quality research articles in almost all branches of medicine. The quality of printing of figures and tables is excellent and comparable to any International journal. An added advantage is nominal publication charges and monthly issue of the journal and more chances of an article being accepted for publication. Moreover being a multi-specialty journal an article concerning a particular specialty has a wider reach of readers of other related specialties also. As an author and reviewer for several years I find this Journal most suitable and highly recommend this Journal."
Best regards,
C.S. Ramesh Babu,
Associate Professor of Anatomy,
Muzaffarnagar Medical College,
Muzaffarnagar.
On Aug 2018




Dr. Arundhathi. S
"Journal of Clinical and Diagnostic Research (JCDR) is a reputed peer reviewed journal and is constantly involved in publishing high quality research articles related to medicine. Its been a great pleasure to be associated with this esteemed journal as a reviewer and as an author for a couple of years. The editorial board consists of many dedicated and reputed experts as its members and they are doing an appreciable work in guiding budding researchers. JCDR is doing a commendable job in scientific research by promoting excellent quality research & review articles and case reports & series. The reviewers provide appropriate suggestions that improve the quality of articles. I strongly recommend my fraternity to encourage JCDR by contributing their valuable research work in this widely accepted, user friendly journal. I hope my collaboration with JCDR will continue for a long time".



Dr. Arundhathi. S
MBBS, MD (Pathology),
Sanjay Gandhi institute of trauma and orthopedics,
Bengaluru.
On Aug 2018




Dr. Mamta Gupta,
"It gives me great pleasure to be associated with JCDR, since last 2-3 years. Since then I have authored, co-authored and reviewed about 25 articles in JCDR. I thank JCDR for giving me an opportunity to improve my own skills as an author and a reviewer.
It 's a multispecialty journal, publishing high quality articles. It gives a platform to the authors to publish their research work which can be available for everyone across the globe to read. The best thing about JCDR is that the full articles of all medical specialties are available as pdf/html for reading free of cost or without institutional subscription, which is not there for other journals. For those who have problem in writing manuscript or do statistical work, JCDR comes for their rescue.
The journal has a monthly publication and the articles are published quite fast. In time compared to other journals. The on-line first publication is also a great advantage and facility to review one's own articles before going to print. The response to any query and permission if required, is quite fast; this is quite commendable. I have a very good experience about seeking quick permission for quoting a photograph (Fig.) from a JCDR article for my chapter authored in an E book. I never thought it would be so easy. No hassles.
Reviewing articles is no less a pain staking process and requires in depth perception, knowledge about the topic for review. It requires time and concentration, yet I enjoy doing it. The JCDR website especially for the reviewers is quite user friendly. My suggestions for improving the journal is, more strict review process, so that only high quality articles are published. I find a a good number of articles in Obst. Gynae, hence, a new journal for this specialty titled JCDR-OG can be started. May be a bimonthly or quarterly publication to begin with. Only selected articles should find a place in it.
An yearly reward for the best article authored can also incentivize the authors. Though the process of finding the best article will be not be very easy. I do not know how reviewing process can be improved. If an article is being reviewed by two reviewers, then opinion of one can be communicated to the other or the final opinion of the editor can be communicated to the reviewer if requested for. This will help one’s reviewing skills.
My best wishes to Dr. Hemant Jain and all the editorial staff of JCDR for their untiring efforts to bring out this journal. I strongly recommend medical fraternity to publish their valuable research work in this esteemed journal, JCDR".



Dr. Mamta Gupta
Consultant
(Ex HOD Obs &Gynae, Hindu Rao Hospital and associated NDMC Medical College, Delhi)
Aug 2018




Dr. Rajendra Kumar Ghritlaharey

"I wish to thank Dr. Hemant Jain, Editor-in-Chief Journal of Clinical and Diagnostic Research (JCDR), for asking me to write up few words.
Writing is the representation of language in a textual medium i e; into the words and sentences on paper. Quality medical manuscript writing in particular, demands not only a high-quality research, but also requires accurate and concise communication of findings and conclusions, with adherence to particular journal guidelines. In medical field whether working in teaching, private, or in corporate institution, everyone wants to excel in his / her own field and get recognised by making manuscripts publication.


Authors are the souls of any journal, and deserve much respect. To publish a journal manuscripts are needed from authors. Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards. Both ways its true "No authors-No manuscripts-No journals" and "No journals–No manuscripts–No authors". Reviewing a manuscript is also a very responsible and important task of any peer-reviewed journal and to be taken seriously. It needs knowledge on the subject, sincerity, honesty and determination. Although the process of reviewing a manuscript is a time consuming task butit is expected to give one's best remarks within the time frame of the journal.
Salient features of the JCDR: It is a biomedical, multidisciplinary (including all medical and dental specialities), e-journal, with wide scope and extensive author support. At the same time, a free text of manuscript is available in HTML and PDF format. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb 2007 of its first issue, it contained 5 articles only, and now in its recent volume published in April 2011, it contained 67 manuscripts. This e-journal is fulfilling the commitments and objectives sincerely, (as stated by Editor-in-chief in his preface to first edition) i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help. JCDR provides authors help in this regards.
Timely publication of journal: Publication of manuscripts and bringing out the issue in time is one of the positive aspects of JCDR and is possible with strong support team in terms of peer reviewers, proof reading, language check, computer operators, etc. This is one of the great reasons for authors to submit their work with JCDR. Another best part of JCDR is "Online first Publications" facilities available for the authors. This facility not only provides the prompt publications of the manuscripts but at the same time also early availability of the manuscripts for the readers.
Indexation and online availability: Indexation transforms the journal in some sense from its local ownership to the worldwide professional community and to the public.JCDR is indexed with Embase & EMbiology, Google Scholar, Index Copernicus, Chemical Abstracts Service, Journal seek Database, Indian Science Abstracts, to name few of them. Manuscriptspublished in JCDR are available on major search engines ie; google, yahoo, msn.
In the era of fast growing newer technologies, and in computer and internet friendly environment the manuscripts preparation, submission, review, revision, etc and all can be done and checked with a click from all corer of the world, at any time. Of course there is always a scope for improvement in every field and none is perfect. To progress, one needs to identify the areas of one's weakness and to strengthen them.
It is well said that "happy beginning is half done" and it fits perfectly with JCDR. It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb 2007. This had been made possible due to the efforts and the hard work put in it. The way the JCDR is improving with every new volume, with good quality original manuscripts, makes it a quality journal for readers. I must thank and congratulate Dr Hemant Jain, Editor-in-Chief JCDR and his team for their sincere efforts, dedication, and determination for making JCDR a fast growing journal.
Every one of us: authors, reviewers, editors, and publisher are responsible for enhancing the stature of the journal. I wish for a great success for JCDR."



Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
E-mail: drrajendrak1@rediffmail.com
On May 11,2011




Dr. Shankar P.R.

"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
Most of the manuscripts are published within 3 to 4 months of their submission if they are found to be suitable after the review process. JCDR is published bimonthly and the accepted articles were usually published in the next issue. Recently, due to the increased volume of the submissions, the review process has become slower and it ?? Section can take from 4 to 6 months for the articles to be reviewed. The journal has an extensive author support system and it has recently introduced a paid expedited review process. The journal also mentions the average time for processing the manuscript under different submission systems - regular submission and expedited review.
Strengths of the journal: The journal has an online first facility in which the accepted manuscripts may be published on the website before being included in a regular issue of the journal. This cuts down the time between their acceptance and the publication. The journal is indexed in many databases, though not in PubMed. The editorial board should now take steps to index the journal in PubMed. The journal has a system of notifying readers through e-mail when a new issue is released. Also, the articles are available in both the HTML and the PDF formats. I especially like the new and colorful page format of the journal. Also, the access statistics of the articles are available. The prepublication and the manuscript tracking system are also helpful for the authors.
Areas for improvement: In certain cases, I felt that the peer review process of the manuscripts was not up to international standards and that it should be strengthened. Also, the number of manuscripts in an issue is high and it may be difficult for readers to go through all of them. The journal can consider tightening of the peer review process and increasing the quality standards for the acceptance of the manuscripts. I faced occasional problems with the online manuscript submission (Pre-publishing) system, which have to be addressed.
Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work."



Dr. P. Ravi Shankar
KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
E-mail: ravi.dr.shankar@gmail.com
On April 2011
Anuradha

Dear team JCDR, I would like to thank you for the very professional and polite service provided by everyone at JCDR. While i have been in the field of writing and editing for sometime, this has been my first attempt in publishing a scientific paper.Thank you for hand-holding me through the process.


Dr. Anuradha
E-mail: anuradha2nittur@gmail.com
On Jan 2020

Important Notice

Reviews
Year : 2022 | Month : February | Volume : 16 | Issue : 2 | Page : ZE01 - ZE05 Full Version

Orthodontic Limitations in Adults: A Review


Published: February 1, 2022 | DOI: https://doi.org/10.7860/JCDR/2022/50504.15932
Subi Singh , Mona Prabhakar , Jasmine Nindra , MS Sidhu , Shikha Ahlawat

1. Postgraduate Student, Department of Orthodontics and Dentofacial Orthopaedics, SGT University, Faculty of Dental Sciences, Gurugram, Haryana, India. 2. Professor, Department of Orthodontics and Dentofacial Orthopaedics, SGT University, Faculty of Dental Sciences, Gurugram, Haryana, India. 3. Senior Lecturer, Department of Orthodontics and Dentofacial Orthopaedics, SGT University, Faculty of Dental Sciences, Gurugram, Haryana, India. 4. Professor and Head, Department of Orthodontics and Dentofacial Orthopaedics, SGT University, Faculty of Dental Sciences, Gurugram, Haryana, India. 5. Postgraduate, Department of Orthodontics and Dentofacial Orthopaedics, SGT University, Faculty of Dental Sciences, Gurugram, Haryana, India.

Correspondence Address :
Subi Singh,
Shree Guru Govind Singh Tricentenery Univeristy (SGT University), Chandu Budhera, Gurugram, Haryana, India.
E-mail: drsubisingh@gmail.com

Abstract

The scope of orthodontics has broadened in the current era. It is no longer limited to the treatment of children and adolescents but includes the treatment of adults that are non growing thereby extending the age limit. The number of adults seeking orthodontic treatment has considerably increased over the past few years as people have become aesthetically conscious and aware of treatment modalities available through channels like internet and social media. While treating adult patients, a multidisciplinary approach should be adopted, taking into consideration several factors like systemic diseases and psychological factors so as to formulate a holistic treatment plan. Orthodontists face challenges in treating older adult patients whose growth is already completed. There are various elements that differentiate adult orthodontic treatment from that of children or adolescents. Therefore, this article highlights the constraints or challenges faced by an orthodontist in treating adult patients.

Keywords

Osteoporosis, Periodontal disease, Perception, Self-concept

Atypical alignment of teeth and jaws is common. Dentofacial aesthetics is one of the important aspects of orthodontic treatment to boost the social and psychological well-being of the patient. It contributes to physical attractiveness, physical health, and beauty lying on the fact that self-perception and self-confidence are influenced by one’s physical attractiveness. Perception of dental appearance, both of oneself and by others is therefore of major importance in Orthodontics. Orthodontic treatment can be done in young as well as adult individuals. Orthodontics in adults (non growing individuals) is not new (1).

During recent times, an increase in adult patients that are non growing has been seen in orthodontic practice. Approximately, 80% of the adults seeking orthodontic treatment is due to the aesthetic norms of the society rather than health or function (2). It necessitates a desparate approach to the treatment of non growing adults than that of growing adolescent individuals due to varied reasons. Growth modification procedures in adults are not applicable due to lack of growth potential in them and thus foists certain constraints or limitations to their treatment which may be challenging for an orthodontist though similarities exist in the management of adults and adolescent orthodontic patients (3).

Limitation in Adult Orthodontics

The limitations in Adult Orthodontic Patients can be Analogous to (4)

Biology:

• Dental status- Pertaining to dental status, the number and the quality of teeth are essential that encompass the absence or presence of any periapical pathology or active caries and the remaining natural tooth substance. Thus, the prognosis of each individual tooth should be taken into consideration (4).
• Periodontal status- In regard to periodontal status, the absence or presence of clinically active gingivitis and periodontitis is important to move teeth without further worsening its periodontal support (4).
• General health- General health is crucial for bone modelling that is generated by orthodontic forces. This is applicable to all patients but the proportion of adult patients with deviations in bone turnover has to be considered while orthodontic treatment planning that is higher in adults than among young patients (4).

Configuration:

• Orthodontic technique- Orthodontic technique in deteriorating dentitions in older adult patients is characterised by a well-defined movement of individual teeth or groups of teeth that can be achieved with continuous arch treatment (4).
• Anchorage- In consideration to the anchorage, thickness of the cortical bone and the density of the trabecular bone in addition to the thickness of the mucosa are factors that affect the prospects of orthodontic treatment. (4).

Reasons for Increased Number of Adults Patients (5)

• Proximity to aesthetic treatment options like lingual orthodontics and invisalign.
• Revolution in recent materials like ceramic brackets and tooth-coloured wires.
• Effective management of skeletal malocclusion with the help of advanced orthognathic surgical procedure.
• Role of dentists in the family.
• Role of social media and visual aids.
• Improved socio-economic status.
• Greater acknowledgement of health and aesthetic concerns.
• Enhanced desire of patients and dentists for treatment of mutilated problems using orthodontically induced tooth movement and fixed prostheses rather than removable restorations.
• Decreased periodontal complications as a result of improved tooth and occlusal function relationship.

LIMITING FACTORS FOR ADULTS IN ORTHODONTIC TREATMENT (6)

Major reasons for the dramatic rise in adult orthodontic treatment include increased social awareness of the availability of orthodontic treatment for adults, an increased appreciation of how orthodontics can facilitate other dental treatment to maintain the dentition, and improvements in orthodontic appliances. A considerable finding in adult patients is that they are apprehensive about enhancing their social acceptance and appearance than function as well as increased social acceptability of appliance therapy (5).

There are various factors among non growing individuals which require special considerations (6).
I. Absence or lack of growth.
II. Perio-restorative problems.
III. Anchorage control
IV. Closure of extraction spaces
V. Temporomandibular Disorders
VI. Psychological factors
VII. Age changes of varying degree
VIII. Treatment Time
IX. Stability
X. Role of Drugs

Orthodontist substantially considers the problem list as the diagnosis. Diagnosis entails the development of a comprehensive database of relevant information. The standard diagnostic methods consist of clinical diagnosis, skeletal diagnosis, temporo-mandibular joint and periodontal diagnosis. During clinical examination, age should be considered as salient as both lip length and lip thickness are related to age (7). Also, less upper tooth substance is visible with increasing age. Following dental examination, periodontal status should be meticulously examined as adults usually have reduced bone level and are frequently seen with periodontal pockets, gingival recession or loss of attachment. The American Board of Orthodontics now recommends evidence of pretreatment periodontal condition for all adult patients (8). An orthodontist treating adult or non growing patients has a key role in diagnosing skeletal as well as temporomandibular joint complications that may worsen with age.

Adult patients require a distinct treatment approach from adolescents due to the following limiting factors:

Absence or Lack of Growth

Appliances for growth alterations (myofunctional appliances) including activator, bionator, twin block or Frankel Regulator cannot be used while treating adult or non growing patients as growth is already complete and limited scope is left for growth manipulation (5). The treatment of non growing patients will result in differences in response to mechanotherapy (9). Therefore, the treatment modalities are confined to dentoalveolar corrections, camouflage treatment or surgical corrections. The force delivery used for treating adults varies in several respects from that used in young growing individual. Skeletal discrepancies cannot be treated by any bone modification as growth is completed. Skeletal malocclusions have to be treated by orthognathic surgery or camouflage. The main consideration in adults is the insubstantial scope for growth modification and functional appliances (6).

Dysfunction of the stomatognathic system can result in excessive wear and abrasion of the dentition causing reduction in lower anterior facial height and deepening of the bite. Also, posterior tooth extraction or extrusion is avoided in adult patients as they can be one of the main etiologic factors of deepening of bite. Relative intrusion of incisors or extrusion of molars is avoided in adult patients with skeletal deep bite as there is a high chance of relapse of this movement. This is because adults have a strong jaw musculature on account of which molars return back to their original position (4).

Thus, it is important to highlight that at adult stage of life there is high potential to relapse during the orthodontic treatment, due to the cessation of growth and reduced ability to adapt to perioral muscles and temporomandibular joint to the new dental positions (10).

Perio-restorative Problems

Adults have pre-existing conditions that might not be present in young growing patients. Before beginning orthodontic treatment in adults, quantitative and qualitative evaluation of bone and periodontal support should be done as they need special consideration while planning anchorage (11). In adolescents, there is usually mild periodontal tissue destruction and is localised to certain teeth, but there is increasing loss of periodontal support with increasing age. Also, posterior tooth extraction should not be done as it causes supra-eruption of the opposing tooth that disrupts the occlusion. This situation causes increased risk of periodontal problems and patient may also lose chewing ability (4).

Periodontal disease is highly prevalent in patients with diabetes mellitus and there is an inter-relationship between the two with poor glycaemic control in diabetic patients with periodontal disease and periodontal tissue destruction diabetic patients (12). Lalla E et al., found the prevalence of periodontitis among different age groups (13). It was 4.8 times higher among diabetic patients than non diabetic patients. Periodontal inflammation can cause disruption of the periodontal fibres and alveolar bone which may disturb the dental equilibrium causing rotation, tilting or drifting of the teeth (14).

Adult patients have heavily restored teeth or endodontically treated teeth including placement of porcelain or metallic crowns, amalgam fillings which pose difficulty during placement of orthodontic appliance (15). Hence, bonding has to be taken into consideration. Bond strength of porcelain may be enhanced by using 9.6% hydrofluoric acid or 1.23% acidulated phosphate fluoride gel, along with silane primers and highly-filled composite resin. Then teeth can be temporarily restored with composite which makes bonding easier (16). Also, any excess adhesive material around the orthodontic attachments should be removed as the surface roughness of adhesive causes more retention of plaque (3). There must be reinforcement of strict oral hygiene procedures as patients with periodontal problems face difficulty to clean such areas. Every restoration must be polished to diminish plaque accumulation. Stainless steel ligature wires must be used instead of elastomeric modules for being less retentive to plaque. Alternatively, self ligating brackets can be used in such situations, as they are designed to be discrete, easy to clean and comfortable, without use of elastic ligature ties or modules which accumulates more plaque (17).

Anchorage Control

Anchorage in orthodontics is a sensitive matter independent of technique or philosophy followed by a clinician. Unwanted side-effects of loss of anchorage are often seen and inadequate anchorage is an important limiting factor of the orthodontic treatment (4). Poor anchorage control can be due to poor perio-restorative status or missing teeth.

Initial stability is essential for maintaining anchorage, but problems associated with oral health in adults like compromised periodontium, loss of bone or reduced bone density or problems associated with systemic alterations of bone metabolism which can be due to a disease or any medication, compromise the anchorage control thus limiting the orthodontic treatment in adults (4).

Also, adults may be reluctant to wear extra-oral anchorage control devices like headgear and it may be necessary to use other methods of anchorage control suchas palatal arches, two step space closure with frictionless mechanics can be used to reduce strain on anchorage or temporary anchorage devices like mini-implants including infrazygomatic implants, mini-plates can also be used to gain anchorage from bone and avoid depending on teeth for anchorage purpose (18).

Closure of Extraction Spaces

Adults usually present with loss of permanent teeth (mostly first molar) with the remaining extraction space. Adults mostly have less bone apposition with reduced vertical bone height in areas of extraction sites and these sites tend to narrow buccolingually. Thus, closure of such sites in itself poses a challenge to the orthodontists and requires reshaping of the cortical bone which responds more slowly than the cancellous bone (6).

Space closure can be difficult in the maxillary posterior region with low sinus as tooth movement through low sinus is restricted. Orthodontic treatment is extended and requires great control of mechanics with missing or extracted tooth. Furthermore, malocclusions in adults may be complicated due to migration of adjacent teeth into the old extraction sites, so functional and aesthetic results can be accomplished with the combination of orthodontics, surgery, and prosthodontic rehabilitation. Other than ancient extraction sites, space closure of recently extracted sites have better predictable results (19).

Temporomandibular Disorders

The role of occlusion in the development of Temporo-Mandibular Disorders (TMD’s) has been investigated thoroughly in orthodontic literature and is a debatable topic. TMD is common in people whether orthodontic treatment is carried out or not. There is no evidence to support the theory that orthodontic treatment causes TMD or cures it, since the cause of TMD is generally being accepted as multifactorial (20). In the general untreated population, 26–59% adult population have been shown to report at least one symptom of TMD (21). According to McNamara JA et al,. (22) with increase in age, signs and symptoms of TMD surge, therefore TMD that arises during the orthodontic therapy may not be related to the undergoing treatment. As there is higher risk of developing TMD in adult patient, even though it may or may not be related to orthodontic treatment, adults may seek orthodontic treatment due to TMD. Therefore, a thorough examination needs to be done for the signs of TMD in adults and explain that the disorder that is developing may not be associated to the orthodontic treatment (22).

Psychological Factors

Grown up patients have high expectations and treatment desires. Also, they are hesitant in accepting the orthodontic appliances that are visible. Tayer BH and Burek MJ found that nearly 74% of adults reveal that they had initial fears with regard to peer reaction to treatment (23).

Prolonged treatment duration, multifaceted nature of treatment, number of visits makes a curious about the details of orthodontic treatment. Patients even demand aesthetic brackets, aligners or lingual brackets mainly for social reasons. With the advancement in technology, it is possible to meet the aesthetic demands of the patient as they prefer less visible bracket system. These include tooth-coloured brackets with Teflon or epoxy coated or Nitanium tooth tone plastic coated archwires. Lingual appliances that are not seen on the labial surface at all. Lately, there has been an increasing demand for clear aligner therapy that has highlighted the public perception of aesthetic consideration offering the greatest advantage of being removable appliance. People adhere more to the guidelines given by the orthodontist like cleanliness, versatile wear, maintaining hygiene. Thus, it is necessary to advise adult patients about the restrictions or do’s and don’ts and unpredictability of the treatment, expanded treatment time and high backslide potential of relapse (24).

Age Changes of Varying Degree

Orthodontic tooth movement as a result of bone modelling and remodelling depends greatly on age related changes of the skeleton. According to Behrents RG, growth in the craniofacial region, is a continuous process that occurs even into later ages of life (25). On application of orthodontic force, adults are more vulnerable to root resorption as with increasing age, vascularisation in periodontal membrane decreases, becomes narrower and more inelastic and the cementum becomes thicker.

Also, the apical third of the root is firmly anchored in adults, posing difficulty in the movement of teeth, predisposing to resorption (26). Changes associated with age include gingival recession, loss of attachment, formation of black triangles or open gingival embrasures. Along with changes in gingiva, age related changes are seen in periodontium and bone as well (3).

Which includes reduced number of fibroblasts with enhanced irregular pattern, increased number of elastic fibres and reduced organic matrix production.

Cortical bone becomes denser while spongy bone reduces with age and structure of bone changes from that of honeycomb appearance to lace network. Also, haversian canals increase in size making the bone porous (6). Apical displacement of marginal bone level is a local factor that influences the biological backgrounds of tooth movement in adults. Therefore, mild forces should be used in adults and adult patients must be informed prior about the risk of root resorption and thoroughly examined for presence of any systemic disease, TMD, perio-restorative problems to check the susceptibility of root resorption (27).

Treatment Time

Commencement of tooth movement takes longer time in adults in contrast to growing patients. Bone remodelling accompanying tooth movement is slow in adults causing decrease in the movement of the teeth. Activation of appliance in adults is done mostly in 3-6 weeks than in adolescents in which activation is done in 2-4 week’s time. Increased treatment time is also found to be associated with iatrogenic effects like root resorption, white spot lesions and gingival inflammation which are interlinked to orthodontic appliances (28).

The delayed response to mechanical stimulus is suggested to be caused by insufficient source of preosteoblasts as a result of decreased vascularisation with increasing age. The duration of orthodontic treatment in adults mainly depends on patient compliance. Total treatment duration can take a little longer or can be at par in non growing patients, if patients cooperate appropriately with the orthodontists, which makes up slower tooth movement initially during tissue reaction (29).

Bisphosphonates (BPN) possibly stimulate the osteoblast activity and inhibit the osteoclastic activity. They are used in the prevention and treatment of osteoporosis in postmenopausal women to increase the bone mineral density and reduce the fracture rate (30). But high doses of I.v. BPN appear to increase the risk of Osteoradionecrosis in the jaws. Thus, careful oral evaluation for active dental problems and guiding the importance of maintaining oral hygiene after the start of treatment is helpful in limiting the development of osteoradionecrosis (31). BPNs can hinder tooth movement and set back the treatment time. Teeth under orthodontic treatment can be retained and anchored by topical application of BPN (32).

There are potential age-related changes that constantly occur throughout life including minute changes in the relationship between the maxilla and mandible and the changes in the pressure of soft tissues on the dentition. Therefore, dentition is a biological environment where changes are constantly occurring and there is potential for changes to occur in the alignment of occlusal relationships and alignment throughout the life and these changes are perhaps considered as normal age changes thus increasing the chances of relapse in adults (33).

Orthodontic treatment should be followed-up for at least five years so that long term stability of the results can be considered in relation to aging, periodontal status, caries, duration of therapy, cost invested, efforts and tooth restorations (34). Also, informed consent should be taken prior to the treatment. An important aspect of informed consent is the need for the patient to completely understand the long-term risk associated with relapse, and appreciate the procedures to minimise the risk.

Stability

Stability is attained only after death. Biological changes occur continuously throughout life. But changes occurring after orthodontic therapy are a combination of the tendency towards the return to the pretreatment situation, which occur mainly in the early post-treatment period, and life-long age-related development (4). It is important to achieve an adequate periodontal and functional condition before finalising the treatment. Teeth may be splinted and permanent retention is usually needed to prevent spontaneous migration of teeth into the extraction space or missing tooth space. Traditional retainers may not be indicated in case of severe periodontal bone loss or mobile teeth. This is mainly due to the fact that, marginal bone loss might have displaced the centre of resistance of the teeth further apically, leading to absence of equilibrium between the forces and the resistance (35).

Adults exhibit higher relapse tendencies compared to adolescents, either due to the tendency of the teeth to move back to their original position or the ageing process that is continuous throughout life, requiring permanent retention in most of the cases (36) like periodontically compromised patients. Also, as in adult patients, movement of teeth is to be accommodated in non growing arches, they have greater incidence of post-treatment relapse (37).

Role of Drugs

Systemic diseases may have a positive or negative effect on tooth movement in adults. During the course of the treatment, medications may be prescribed for pain or TMDs but apart from these, patients may also consume vitamins and minerals for various systemic diseases (Table/Fig 1) (38).

Conclusion

Adults tend to be excellent orthodontic patients, due to their high motivation and co-operation. Since expectations may also be high, the limitations of orthodontic treatment must be made clear. In the current era, more consideration is paid to understand the orthodontic limitations in adults. While treating an adult for orthodontic concerns, an individualised custom-made treatment plan according to the patient’s requirement and condition that is crucial for proper outcome and accomplishment of treatment on the basis of careful assessment of complex interaction of various biological, mechanical and psychological factors.

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Tables and Figures
[Table / Fig - 1]
DOI and Others

DOI: 10.7860/JCDR/2022/50504.15932

Date of Submission: May 27, 2021
Date of Peer Review: Jul 24, 2021
Date of Acceptance: Nov 23, 2021
Date of Publishing: Feb 01, 2022

AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? NA
• Was informed consent obtained from the subjects involved in the study? NA
• For any images presented appropriate consent has been obtained from the subjects. NA

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