Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Dr Mohan Z Mani

"Thank you very much for having published my article in record time.I would like to compliment you and your entire staff for your promptness, courtesy, and willingness to be customer friendly, which is quite unusual.I was given your reference by a colleague in pathology,and was able to directly phone your editorial office for clarifications.I would particularly like to thank the publication managers and the Assistant Editor who were following up my article. I would also like to thank you for adjusting the money I paid initially into payment for my modified article,and refunding the balance.
I wish all success to your journal and look forward to sending you any suitable similar article in future"

Dr Mohan Z Mani,
Professor & Head,
Department of Dermatolgy,
Believers Church Medical College,
Thiruvalla, Kerala
On Sep 2018

Prof. Somashekhar Nimbalkar

"Over the last few years, we have published our research regularly in Journal of Clinical and Diagnostic Research. Having published in more than 20 high impact journals over the last five years including several high impact ones and reviewing articles for even more journals across my fields of interest, we value our published work in JCDR for their high standards in publishing scientific articles. The ease of submission, the rapid reviews in under a month, the high quality of their reviewers and keen attention to the final process of proofs and publication, ensure that there are no mistakes in the final article. We have been asked clarifications on several occasions and have been happy to provide them and it exemplifies the commitment to quality of the team at JCDR."

Prof. Somashekhar Nimbalkar
Head, Department of Pediatrics, Pramukhswami Medical College, Karamsad
Chairman, Research Group, Charutar Arogya Mandal, Karamsad
National Joint Coordinator - Advanced IAP NNF NRP Program
Ex-Member, Governing Body, National Neonatology Forum, New Delhi
Ex-President - National Neonatology Forum Gujarat State Chapter
Department of Pediatrics, Pramukhswami Medical College, Karamsad, Anand, Gujarat.
On Sep 2018

Dr. Kalyani R

"Journal of Clinical and Diagnostic Research is at present a well-known Indian originated scientific journal which started with a humble beginning. I have been associated with this journal since many years. I appreciate the Editor, Dr. Hemant Jain, for his constant effort in bringing up this journal to the present status right from the scratch. The journal is multidisciplinary. It encourages in publishing the scientific articles from postgraduates and also the beginners who start their career. At the same time the journal also caters for the high quality articles from specialty and super-specialty researchers. Hence it provides a platform for the scientist and researchers to publish. The other aspect of it is, the readers get the information regarding the most recent developments in science which can be used for teaching, research, treating patients and to some extent take preventive measures against certain diseases. The journal is contributing immensely to the society at national and international level."

Dr Kalyani R
Professor and Head
Department of Pathology
Sri Devaraj Urs Medical College
Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka
On Sep 2018

Dr. Saumya Navit

"As a peer-reviewed journal, the Journal of Clinical and Diagnostic Research provides an opportunity to researchers, scientists and budding professionals to explore the developments in the field of medicine and dentistry and their varied specialities, thus extending our view on biological diversities of living species in relation to medicine.
‘Knowledge is treasure of a wise man.’ The free access of this journal provides an immense scope of learning for the both the old and the young in field of medicine and dentistry as well. The multidisciplinary nature of the journal makes it a better platform to absorb all that is being researched and developed. The publication process is systematic and professional. Online submission, publication and peer reviewing makes it a user-friendly journal.
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I wish JCDR a great success and I hope that journal will soar higher with the passing time."

Dr Saumya Navit
Professor and Head
Department of Pediatric Dentistry
Saraswati Dental College
On Sep 2018

Dr. Arunava Biswas

"My sincere attachment with JCDR as an author as well as reviewer is a learning experience . Their systematic approach in publication of article in various categories is really praiseworthy.
Their prompt and timely response to review's query and the manner in which they have set the reviewing process helps in extracting the best possible scientific writings for publication.
It's a honour and pride to be a part of the JCDR team. My very best wishes to JCDR and hope it will sparkle up above the sky as a high indexed journal in near future."

Dr. Arunava Biswas
MD, DM (Clinical Pharmacology)
Assistant Professor
Department of Pharmacology
Calcutta National Medical College & Hospital , Kolkata

Dr. C.S. Ramesh Babu
" Journal of Clinical and Diagnostic Research (JCDR) is a multi-specialty medical and dental journal publishing high quality research articles in almost all branches of medicine. The quality of printing of figures and tables is excellent and comparable to any International journal. An added advantage is nominal publication charges and monthly issue of the journal and more chances of an article being accepted for publication. Moreover being a multi-specialty journal an article concerning a particular specialty has a wider reach of readers of other related specialties also. As an author and reviewer for several years I find this Journal most suitable and highly recommend this Journal."
Best regards,
C.S. Ramesh Babu,
Associate Professor of Anatomy,
Muzaffarnagar Medical College,
On Aug 2018

Dr. Arundhathi. S
"Journal of Clinical and Diagnostic Research (JCDR) is a reputed peer reviewed journal and is constantly involved in publishing high quality research articles related to medicine. Its been a great pleasure to be associated with this esteemed journal as a reviewer and as an author for a couple of years. The editorial board consists of many dedicated and reputed experts as its members and they are doing an appreciable work in guiding budding researchers. JCDR is doing a commendable job in scientific research by promoting excellent quality research & review articles and case reports & series. The reviewers provide appropriate suggestions that improve the quality of articles. I strongly recommend my fraternity to encourage JCDR by contributing their valuable research work in this widely accepted, user friendly journal. I hope my collaboration with JCDR will continue for a long time".

Dr. Arundhathi. S
MBBS, MD (Pathology),
Sanjay Gandhi institute of trauma and orthopedics,
On Aug 2018

Dr. Mamta Gupta,
"It gives me great pleasure to be associated with JCDR, since last 2-3 years. Since then I have authored, co-authored and reviewed about 25 articles in JCDR. I thank JCDR for giving me an opportunity to improve my own skills as an author and a reviewer.
It 's a multispecialty journal, publishing high quality articles. It gives a platform to the authors to publish their research work which can be available for everyone across the globe to read. The best thing about JCDR is that the full articles of all medical specialties are available as pdf/html for reading free of cost or without institutional subscription, which is not there for other journals. For those who have problem in writing manuscript or do statistical work, JCDR comes for their rescue.
The journal has a monthly publication and the articles are published quite fast. In time compared to other journals. The on-line first publication is also a great advantage and facility to review one's own articles before going to print. The response to any query and permission if required, is quite fast; this is quite commendable. I have a very good experience about seeking quick permission for quoting a photograph (Fig.) from a JCDR article for my chapter authored in an E book. I never thought it would be so easy. No hassles.
Reviewing articles is no less a pain staking process and requires in depth perception, knowledge about the topic for review. It requires time and concentration, yet I enjoy doing it. The JCDR website especially for the reviewers is quite user friendly. My suggestions for improving the journal is, more strict review process, so that only high quality articles are published. I find a a good number of articles in Obst. Gynae, hence, a new journal for this specialty titled JCDR-OG can be started. May be a bimonthly or quarterly publication to begin with. Only selected articles should find a place in it.
An yearly reward for the best article authored can also incentivize the authors. Though the process of finding the best article will be not be very easy. I do not know how reviewing process can be improved. If an article is being reviewed by two reviewers, then opinion of one can be communicated to the other or the final opinion of the editor can be communicated to the reviewer if requested for. This will help one’s reviewing skills.
My best wishes to Dr. Hemant Jain and all the editorial staff of JCDR for their untiring efforts to bring out this journal. I strongly recommend medical fraternity to publish their valuable research work in this esteemed journal, JCDR".

Dr. Mamta Gupta
(Ex HOD Obs &Gynae, Hindu Rao Hospital and associated NDMC Medical College, Delhi)
Aug 2018

Dr. Rajendra Kumar Ghritlaharey

"I wish to thank Dr. Hemant Jain, Editor-in-Chief Journal of Clinical and Diagnostic Research (JCDR), for asking me to write up few words.
Writing is the representation of language in a textual medium i e; into the words and sentences on paper. Quality medical manuscript writing in particular, demands not only a high-quality research, but also requires accurate and concise communication of findings and conclusions, with adherence to particular journal guidelines. In medical field whether working in teaching, private, or in corporate institution, everyone wants to excel in his / her own field and get recognised by making manuscripts publication.

Authors are the souls of any journal, and deserve much respect. To publish a journal manuscripts are needed from authors. Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards. Both ways its true "No authors-No manuscripts-No journals" and "No journals–No manuscripts–No authors". Reviewing a manuscript is also a very responsible and important task of any peer-reviewed journal and to be taken seriously. It needs knowledge on the subject, sincerity, honesty and determination. Although the process of reviewing a manuscript is a time consuming task butit is expected to give one's best remarks within the time frame of the journal.
Salient features of the JCDR: It is a biomedical, multidisciplinary (including all medical and dental specialities), e-journal, with wide scope and extensive author support. At the same time, a free text of manuscript is available in HTML and PDF format. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb 2007 of its first issue, it contained 5 articles only, and now in its recent volume published in April 2011, it contained 67 manuscripts. This e-journal is fulfilling the commitments and objectives sincerely, (as stated by Editor-in-chief in his preface to first edition) i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help. JCDR provides authors help in this regards.
Timely publication of journal: Publication of manuscripts and bringing out the issue in time is one of the positive aspects of JCDR and is possible with strong support team in terms of peer reviewers, proof reading, language check, computer operators, etc. This is one of the great reasons for authors to submit their work with JCDR. Another best part of JCDR is "Online first Publications" facilities available for the authors. This facility not only provides the prompt publications of the manuscripts but at the same time also early availability of the manuscripts for the readers.
Indexation and online availability: Indexation transforms the journal in some sense from its local ownership to the worldwide professional community and to the public.JCDR is indexed with Embase & EMbiology, Google Scholar, Index Copernicus, Chemical Abstracts Service, Journal seek Database, Indian Science Abstracts, to name few of them. Manuscriptspublished in JCDR are available on major search engines ie; google, yahoo, msn.
In the era of fast growing newer technologies, and in computer and internet friendly environment the manuscripts preparation, submission, review, revision, etc and all can be done and checked with a click from all corer of the world, at any time. Of course there is always a scope for improvement in every field and none is perfect. To progress, one needs to identify the areas of one's weakness and to strengthen them.
It is well said that "happy beginning is half done" and it fits perfectly with JCDR. It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb 2007. This had been made possible due to the efforts and the hard work put in it. The way the JCDR is improving with every new volume, with good quality original manuscripts, makes it a quality journal for readers. I must thank and congratulate Dr Hemant Jain, Editor-in-Chief JCDR and his team for their sincere efforts, dedication, and determination for making JCDR a fast growing journal.
Every one of us: authors, reviewers, editors, and publisher are responsible for enhancing the stature of the journal. I wish for a great success for JCDR."

Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
On May 11,2011

Dr. Shankar P.R.

"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
Most of the manuscripts are published within 3 to 4 months of their submission if they are found to be suitable after the review process. JCDR is published bimonthly and the accepted articles were usually published in the next issue. Recently, due to the increased volume of the submissions, the review process has become slower and it ?? Section can take from 4 to 6 months for the articles to be reviewed. The journal has an extensive author support system and it has recently introduced a paid expedited review process. The journal also mentions the average time for processing the manuscript under different submission systems - regular submission and expedited review.
Strengths of the journal: The journal has an online first facility in which the accepted manuscripts may be published on the website before being included in a regular issue of the journal. This cuts down the time between their acceptance and the publication. The journal is indexed in many databases, though not in PubMed. The editorial board should now take steps to index the journal in PubMed. The journal has a system of notifying readers through e-mail when a new issue is released. Also, the articles are available in both the HTML and the PDF formats. I especially like the new and colorful page format of the journal. Also, the access statistics of the articles are available. The prepublication and the manuscript tracking system are also helpful for the authors.
Areas for improvement: In certain cases, I felt that the peer review process of the manuscripts was not up to international standards and that it should be strengthened. Also, the number of manuscripts in an issue is high and it may be difficult for readers to go through all of them. The journal can consider tightening of the peer review process and increasing the quality standards for the acceptance of the manuscripts. I faced occasional problems with the online manuscript submission (Pre-publishing) system, which have to be addressed.
Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work."

Dr. P. Ravi Shankar
KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
On April 2011

Dear team JCDR, I would like to thank you for the very professional and polite service provided by everyone at JCDR. While i have been in the field of writing and editing for sometime, this has been my first attempt in publishing a scientific paper.Thank you for hand-holding me through the process.

Dr. Anuradha
On Jan 2020

Important Notice

Original article / research
Year : 2023 | Month : November | Volume : 17 | Issue : 11 | Page : MC05 - MC10 Full Version

Application of Coblation for Airway Disorder Management in ENT Practice: A Prospective Cohort Study

Published: November 1, 2023 | DOI:
Pooja Shriwastav, Hetal Marfatia, Anoushka Sahai, Ashwini Kumar Gaikwad, Monankita Sharma

1. Senior Resident, Department of ENT, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India. 2. Head, Department of ENT, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India. 3. Senior Resident, Department of ENT, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India. 4. Senior Resident, Department of ENT, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India. 5. Resident, Department of ENT, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India.

Correspondence Address :
Dr. Anoushka Sahai,
Acharya Dhonde Marg, Parel, Mumbai-400012, Maharashtra, India.


Introduction: Coblation, a form of radiofrequency surgery, involves using radiofrequency energy to create a plasma field through a conductive medium. This technique dissociates the medium into high-energy ions that break intercellular bonds, leading to tissue dissociation. Coblation is performed at low temperatures, making it less painful and conducive to healing in airway surgeries.

Aim: To evaluate the indications, advantages, and outcomes of coblation-assisted airway surgeries.

Materials and Methods: A prospective cohort study was conducted from November 2019 to May 2021 at the Department of Ear, Nose and Throat (ENT), Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India. Patients with breathing difficulties, voice changes, or airway obstruction symptoms were included. A detailed history, physical examination, and diagnostic procedures were carried out. Coblation was employed under general anaesthesia for laryngeal or tracheal pathology. Data on intraoperative findings, blood loss, hospital stay, and postoperative improvements were recorded in a worksheet-based program, Numbers version 13.1 for macOS. Deductions based on the data were presented using bar charts and diagrams. Continuous variables were summarised using summary statistics, while categorical values were estimated using frequencies and percentages.

Results: A total of 15 patients underwent coblation-assisted surgeries. Breathlessness was the most common symptom 11 (73.33%), followed by stridor in 10 (66.67%) and decreased oxygen levels in 8 (53.3%) were observed. Indirect laryngoscopy showed no findings compared to 70-degree scopy in detecting subglottic stenosis. Intraoperatively, 40% had Grade-II, and 27% had Grade-III subglottic stenosis. The average postoperative stay was five days. At one month, 73% showed improvement, particularly those with subglottic stenosis, while no improvement was seen in 27% of cases.

Conclusion: Coblation-assisted airway surgeries offer benefits like minimal collateral damage and reduced blood loss. In this study, 73% of patients showed improvement, suggesting coblation’s potential advantages over other modalities. Although cost remains a concern, coblation’s ability to reduce postoperative morbidity and improve healing time makes it a promising tool in airway surgeries.


Airways, Angiofibroma, Endoscopy, Haemostasis, Laryngostenosis, Papillomatosis, Radiofrequency

Coblation (Controlled Ablation) technology has emerged as a revolutionary tool in the field of airway surgeries within ENT medicine, revolutionising the way delicate procedures are performed with enhanced precision and minimal tissue damage (1). This innovative technique harnesses the principles of controlled plasma-mediated ablation, offering a superior alternative to traditional methods.

At the heart of coblation technology lies its intricate mechanism, which involves the application of radiofrequency energy to a conductive medium, often a saline solution. The energy excites the ions within the medium, forming a precisely controlled plasma field due to the dissociation of saline into high-energy ions (sodium and chloride ions). This plasma, while maintaining a relatively low temperature (between 60°C and 70°C), efficiently breaks down tissue on a molecular level. As a result, tissue is gently disintegrated without the undesirable collateral damage associated with high-temperature cautery techniques. This finely tuned process ensures that surrounding healthy tissue remains largely unaffected, leading to reduced postoperative pain, faster recovery times, and improved patient outcomes (2).

The most compelling benefit of coblation is its ability to operate at lower temperatures, thereby mitigating the risks of thermal injury to adjacent tissues. This translates to reduced scarring, less disruption of delicate structures, and minimised complications during airway surgeries. Moreover, the precision of coblation technology allows for intricate procedures in challenging anatomical areas, such as the vocal cords, trachea, nasal passages, tonsils, and adenoids, where the preservation of healthy tissue is paramount for optimal functionality (3).

The present study was conducted at the tertiary care centre to evaluate the indications, advantages, and outcomes of coblation-assisted airway surgeries. During the course of the study, the importance of thorough clinical and radiological evaluations was highlighted to accurately diagnose various airway pathologies presenting at the centre.

Material and Methods

A single-centre prospective cohort study was conducted at the Department of ENT of Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India from November 2019 to May 2021. The study was conducted in accordance with ethical standards and received approval from the Institutional Ethics Committee (IEC) (IEC(II)/OUT/679/2020) on December 31, 2020, for project number EC/141/2019. Consents were obtained from the patients using the approved format provided by the ethics committee.

Inclusion criteria: Patients who presented to the ENT-Outpatient Department (OPD) with symptoms indicating airway pathology. These symptoms included stridor, breathlessness, fall in oxygen saturation, changes in voice, nasal obstruction, and other miscellaneous symptoms.

Exclusion criteria: Patients with tonsillar-adenoid hypertrophy or those deemed unfit for surgery were excluded from the study.

Due to the COVID-19 pandemic and the resulting lockdown in India, the number of elective procedures performed was significantly reduced as our hospital served as a COVID-19 care centre. Additionally, the lack of public transportation during the lockdown prevented patients from seeking medical care. Therefore, the study included patients who presented to the department during the pandemic after proper screening for COVID-19 infection.

Before surgery, a detailed history of presenting complaints, present illness, past medical history, and personal history was recorded. Special attention was given to rule out any previous surgeries or past traumas. Physical examinations were conducted, including anterior rhinoscopy, diagnostic nasal endoscopy, indirect laryngoscopy, and 70-degree scopy. All patients underwent Computed Tomography (CT) scans from the skull base to the mediastinum with contrast, including the paranasal sinuses, to assess the level of obstruction before planning for surgery.

Patients with tracheal/laryngeal stenosis were graded preoperatively based on severity and compared with postoperative grading. The Cotton-Myer grading system was used for the paediatric age group, with Grade 1 indicating 0-50% obstruction, Grade 2 indicating 51-70% obstruction, Grade 3 indicating 71-99% obstruction, and Grade 4 indicating no detectable lumen (4).

The McCaffery classification was utilised for grading laryngotracheal stenosis in adults based on the subsites and length of the stenosis. Stage 1 encompassed subglottic or tracheal lesions less than 1 cm in length, Stage 2 involved subglottic lesions longer than 1 cm without tracheal involvement, Stage 3 included subglottic lesions with tracheal involvement but not affecting the glottis, and Stage 4 consisted of subglottic, tracheal, and glottic lesions with fixed vocal cords (5).

Patients received counseling regarding the nature of the disease, available treatment options, benefits and limitations of surgery, postoperative care, postoperative medical treatment, and the potential for success or complications. Prior to surgery, all patients were started on prophylactic broad-spectrum antibiotics (amoxicillin-clavulanic acid) with the dosage adjusted based on their weight. Patients with laryngotracheal pathologies underwent preoperative nebulisation with budesonide. In cases of Juvenile Nasopharyngeal Angiofibroma (JNAF), preoperative embolisation was performed to reduce tumour vascularity. The goal of these interventions was to minimise airway secretions, oedema, and facilitate bronchodilation in lower airway procedures. Nebulisation using budecort and levosalbutamol was administered. For upper airway procedures, nasal decongestion was achieved by applying a patty dipped in a solution of 4% lignocaine plus 4cc adrenaline.

In cases of laryngeal or tracheal pathology, the procedure was performed under general anaesthesia with the patient in a supine position. Orotracheal intubation or intermittent apnoea was used for tracheal pathology. The patient was placed in Boyce’s position, and a micro-laryngoscope with chest suspension was used to open their mouth wide (6). After positioning the direct laryngoscope, the laryngeal lesions or tracheal pathology were fully visualised, and the micro-laryngoscope tube was pushed posteriorly.

The Laryngeal Coblation Wand was then introduced transorally, set to 5 for coblation and 3 for coagulation. Saline irrigation and a suction apparatus were connected via tubing. The tissue was gently coblated and separated from the laryngeal lesions using the coblator. A laser endotracheal tube was unnecessary since the risk of fire was not present. The base of the laryngeal lesion was completely coblated, ensuring no gross remnant lesions remained.

Any bleeding points were immediately cauterised, with minimal damage to the adjacent healthy mucosa.
For nasal pathology, coblation system for sinonasal tumours were utilised. The mass was dissected using the coblator wand and removed in its entirety. Any bleeding points were cauterised using the coagulation mode. Hemostasis was achieved with minimal blood loss.

Postoperatively, patients with laryngotracheal stenosis who underwent coblation-assisted surgery were admitted to the postoperative ward. They were given a course of steroids and antibiotics (dexamethasone in tapering doses and broad-spectrum antibiotics, such as amoxicillin-clavulanic acid, as per departmental protocol) to prevent postoperative oedema and infection. Patients who underwent glottic procedures were advised complete voice rest for 10 days to facilitate proper wound healing. In the case of nasopharyngeal mass removal, nasal packs were removed on postoperative day 2.

All patients were followed-up at intervals of one month, three months, and six months after surgery for assessment. Assessment included findings from the 70-degree examination and airway assessment under general anaesthesia for laryngotracheal pathologies. Stenosis grade was determined in cases of stenosis. For nasal and palatal pathologies, endoscopy was performed to check for recurrence or new pathology.

Statistical Analysis

All the data obtained were recorded in a predesigned case record form. The data obtained from all patient case records were entered into a worksheet-based program, specifically Numbers version 13.1 for macOS. Relevant deductions based on the data were presented using bar charts and diagrams. Summary statistics were used to summarize continuous variables, while frequencies and percentages were calculated for categorical values.


The present study included 15 cases in which coblation-assisted surgery was performed, out of which 9 (60%) were males and 6 (40%) were females.

Among the 15 patients, breathlessness was the most prevalent symptom 11 (73.3%), followed closely by stridor 10 (66.67%). Nasal obstruction and miscellaneous symptoms, including epistaxis and oral mass, were less common, each affecting 6.67% of the patients (Table/Fig 1),(Table/Fig 2).

In the present study, indirect laryngoscopy and 70-degree scopy were conducted in all patients, except for the patient with a palatal cyst where it was not possible due to complete obstruction of the oral cavity and oropharynx. Out of 14 patients (Table/Fig 3), vocal cord in a paramedian position and polypoidal masses on the anterior commissure were each identified in one patient through indirect laryngoscopy and the 70-degree examination. Glottic stenosis was found in two patients using both methods. Subglottic stenosis was exclusively detected in four (28.57%) patients via the 70-degree examination. In the majority of cases, no significant findings were observed, with 10 patients identified through indirect laryngoscopy and six through the 70-degree examination.

The aetiologies identified in the study were classified based on anatomical site into the laryngo-tracheal region, nasopharyngeal and sinuses, and oral and oropharyngeal region (Table/Fig 4).

In the present study, subglottic narrowing was observed in 8 (53.3%) cases on CT scan [Table/Fig-5,6]. Radiological investigation was not conducted for the patient with a palatal mass.

Among the 15 patients, the most common intraoperative finding (Table/Fig 7) was adult Grade-II subglottic stenosis (five patients) (Table/Fig 8), followed by adult Grade-III subglottic stenosis (two patients) and adult Grade-III glottic stenosis (two patients). Other findings included granulations (Table/Fig 9), small polypoidal masses (laryngeal papillomatosis), bilateral abductor vocal cord palsy with a minimal chink, a pinkish globular mass in the left nasal cavity (Table/Fig 10), and a large palatal mass in one patient each.

Intraoperative blood loss was less than 10 mL in 13 patients who underwent coblation-assisted surgeries for laryngotracheal pathologies. It was approximately 15 mL for the patient with palatal mass excision and approximately 600 mL in the patient who underwent JNAF excision.

The majority of the patients (60%) in the present study had a hospital stay of approximately five days after coblation-assisted surgeries (Table/Fig 11).

At the end of one month, five patients improved from Grade-II to Grade-I subglottic stenosis, followed by two patients who improved from Grade-III subglottic stenosis to Grade-II subglottic stenosis. No improvement was found in three patients, out of which two patients had Grade-III subglottic stenosis and one patient had Grade-II subglottic stenosis. One patient had minimal scar tissue over the posterior subglottis. The patient with laryngeal papillomatosis had minimal scarring in the subglottis in the postoperative period. The patient with bilateral vocal cord palsy showed no improvement on follow-up. The remaining two patients (patients with JNAF and palatal cyst) showed good results in the postoperative period. Postoperative changes seen in the first month remained almost the same at the end of the third and sixth months (Table/Fig 12).

The majority of the patients, showed improvement, while no improvement was noticed in 4 (27%) of the cases (Table/Fig 13).


Airways refer to the passages through which air travels in and out of the respiratory system. They are divided into two main sections: groupthe upper airways, which include the nose, mouth, pharynx, and larynx, and the lower airways, comprising the trachea beyond the carina, bronchi, and lungs. These divisions play a crucial role in maintaining proper airflow and filtering and conditioning the inhaled air (7).

The present study was conducted in the Department of ENT at a tertiary care hospital in Mumbai to highlight the importance of coblation in various airway procedures.

Study comprised 15 patients, with the majority (60%) being males and 40% being females. In the present study, the majority of cases were in the age group between 31 to 40 years, followed by the younger age groups. Comparing different age groups with affected airway aetiologies is not significant as it depends on the availability of cases at a particular centre. Several studies have been undertaken that highlight the importance of coblation in different age groups (8),(9).

With the development of the healthcare sector, more patients are presenting at an earlier stage of the disease, enabling us to operate on them at a younger age. Coblation used in these patients leads to a rapid improvement in symptoms and shorter hospital stays (10),(11).

The majority of the patients in present study had laryngeal or tracheal pathology, and hence breathlessness was one of the most common symptoms among them. It was present in 11 patients, out of which 10 had stridor, and decreased oxygen levels were observed in eight of them. Al-Bazzaz F et al., and Geffin B have reported that a laryngo-tracheal narrowing that reduces the airway diameter to 8 mm produces symptoms during exertion, while a stenosis that reduces the airway to 5 mm causes inspiratory obstruction and stridor at rest (12),(13).

Most of the patients presented with respiratory distress (73.33%) and a fall in oxygen saturation, along with stridor (53.33%). Chan CL et al., conducted a study on 10 patients, where all of them presented with a certain degree of respiratory distress and two had marked stridor (9). Respiratory distress and/or stridor are not seen unless there is an obstruction in the central airway, which can lead to acute airway obstruction, often a dire medical emergency. A drop in oxygen saturation is an alarming sign and indicates an acute airway obstruction, which is more commonly seen in glottic and subglottic pathologies (14),(15).

During 70-degree scopy, airway obstruction was found in eight patients, whereas indirect laryngoscopy detected airway pathology in only four cases. Indirect laryngoscopy showed no findings compared to 70-degree scopy in detecting subglottic stenosis. It can be concluded that 70-degree scopy provides an enhanced view, better clarity, and improved visualisation of hidden areas compared to indirect laryngoscopy. Therefore, subglottic stenosis was evident on 70-degree scopy, which was not visulised on indirect laryngoscopy.

Using a 70-degree scope to visualise laryngeal lesions provides a better understanding of the pathology as it offers a clearer field of vision and reduces the chance of fogging, enabling visualisation of hidden areas on indirect laryngoscopy (16),(17).

However, CT scan has become the investigation of choice before surgery to determine the exact site and extent of the lesion. Virtual bronchoscopy, in particular, is noteworthy as it provides a 3D reconstruction of the airway, aiding in better understanding of the location and extent of the lesion (18),(19). As part of our protocol, CT scan was performed on all the patients, which revealed subglottic stenosis in 53.3% and glottic stenosis in 20% of cases. Therefore, a CT scan may be the best tool for diagnosing airway compromise.

CT is a valuable and sensitive imaging modality for detecting airway pathologies (20). All patients underwent coblation-assisted airway surgery under general anaesthesia. Intraoperative findings were noted, revealing Grade-II subglottic stenosis in 40% of patients and Grade-III subglottic stenosis in 27% of cases. The remaining 33% of cases had other causes of upper airway obstruction.

Coblation was used to release laryngeal obstructions, and in the majority of cases (87%), blood loss was less than 10 mL. There was minimal collateral damage and limited scar tissue formation, consistent with other studies (4),(9),(21),(22).

The average hospital stay observed in the majority of the patients was five days, with no significant postoperative complications.

In present study, five patients showed improvement from Grade-II to Grade-I subglottic stenosis, while two patients improved from Grade-III to Grade-II subglottic stenosis. However, three cases did not show any improvement. Similar results have been reported in studies on coblation-assisted subglottic stenosis release (23). Huang J et al., have also emphasised the precise and rapid ablation integrated with suction and coagulation functions of this technique compared to traditional surgical resection and anastomosis (24).

One case of laryngeal papillomatosis that was successfully removed using coblation. On follow-up, the patient did not show any recurrence. She CP et al., studied 21 cases of laryngeal papillomatosis treated with coblation and reported four cases of recurrence (25). Few long-term follow-up studies have shown a reduction in the frequency of disease recurrence per year per patient with increasing age, suggesting that the disease may improve as immunity improves (26). However, in the present study, the presence of a single patient and a shorter follow-up period can be confounding factors.

In this study, a patient with bilateral abductor vocal cord palsy was treated using Dennis Kashima’s surgery with coblation. However, the patient did not showed significant improvement on follow-up. This finding was not in line with the study conducted by Benninger MS et al., which demonstrated a 100% improvement in cases of bilateral vocal cord palsy without postoperative stenosis, concluding that this technique was a safe and effective approach for treating bilateral abductor vocal cord palsy (27). The non concordance in present study may be attributed to the presence of a single case compared to other studies. Moreover, it has been postulated that under-correction of the airway is better than over-correction, as it allows for simpler revision surgery if needed. Over-correction during the initial airway procedure often results in a poorer voice outcome and can make revision surgery more challenging (28). In our patient, fibrosis had developed, which is considered a common phenomenon (29), and it can be reduced by preserving the inter-arytenoid mucosa.

JNAF is a benign, locally invasive vascular tumour that typically affects young males and is located in the sinonasal region. Due to the absence of a tunica media layer, this tumour is prone to intraoperative bleeding, which can limit resection and increase the risk of complications. In present study, endoscopic JNAF excision using the coblation technique resulted in minimal intraoperative blood loss and only postoperative fibrotic changes on follow-up was observed, with no evidence of recurrence in the patient (30).

A similar study conducted by Cannon DE et al., on a series of four patients who underwent coblation-assisted endoscopic resection also suggested that coblation is a relatively safe and efficient modality (31). It reduces bleeding, decreases the need for instrumentation, and improves visualisation during surgery.

In present study, on subsequent follow-up at one month, three months, and six months, 73% of the patients showed improvement, while no improvement was seen in 27% of the cases. Coblation reduces postoperative morbidity, and direct endoscopic visualisation ensures complete excision of the pathology. The use of small tips for dissection allows access to all areas, resulting in a significant reduction in residual tissue. Additionally, minimal damage to surrounding tissue is an added advantage, leading to shorter hospital stays. However, the high cost of the coblator wand limits its use, particularly in patients from lower socio-economic backgrounds.

This study highlights the potential of coblation technology to revolutionise airway surgeries, but further research and larger-scale studies are necessary to establish its efficacy across a broader patient population.


The study is limited by a small sample size, which consisted of only 15 patients. This sample size was chosen due to the limited availability of patients at the tertiary care centre during the COVID-19 pandemic. The pandemic resulted in a reduced number of patients seeking medical care, as well as our hospital being designated as a COVID-19 referral centre during the study period. Additionally, our hospital primarily serves the economically disadvantaged population, which further limited patient recruitment due to the lack of financial support for acquiring the expensive wands required for coblation surgeries.

Another limitation was that the study was conducted at a single tertiary care centre, which limits the diversity of patient demographics and clinical presentations. This may affect the generalisability of the findings to a broader population.

It is important to acknowledge these limitations and consider them when interpreting the results of the study. Further research with larger sample sizes and multicentre studies are needed to overcome these limitations and provide more robust evidence regarding the efficacy of coblation in airway surgeries.


Coblation-assisted surgeries offer precise treatment for various pathologies, leading to positive outcomes in conditions such as subglottic stenosis and laryngeal papillomatosis. The study showed that 73% of patients demonstrated improvement after undergoing coblation-assisted procedures, highlighting the potential benefits of this technique compared to traditional methods. Additionally, the study revealed that patients who underwent coblation-assisted surgeries experienced shorter hospital stays, with the majority requiring only five days of hospitalisation. Furthermore, these patients also showed improved healing.


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DOI and Others

DOI: 10.7860/JCDR/2023/66953.18665

Date of Submission: Aug 08, 2023
Date of Peer Review: Aug 25, 2023
Date of Acceptance: Oct 07, 2023
Date of Publishing: Nov 01, 2023

• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? Yes
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes

• Plagiarism X-checker: Aug 09, 2023
• Manual Googling: Sep 14, 2023
• iThenticate Software: Oct 05, 2023 (5%)

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