Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Dr Mohan Z Mani

"Thank you very much for having published my article in record time.I would like to compliment you and your entire staff for your promptness, courtesy, and willingness to be customer friendly, which is quite unusual.I was given your reference by a colleague in pathology,and was able to directly phone your editorial office for clarifications.I would particularly like to thank the publication managers and the Assistant Editor who were following up my article. I would also like to thank you for adjusting the money I paid initially into payment for my modified article,and refunding the balance.
I wish all success to your journal and look forward to sending you any suitable similar article in future"



Dr Mohan Z Mani,
Professor & Head,
Department of Dermatolgy,
Believers Church Medical College,
Thiruvalla, Kerala
On Sep 2018




Prof. Somashekhar Nimbalkar

"Over the last few years, we have published our research regularly in Journal of Clinical and Diagnostic Research. Having published in more than 20 high impact journals over the last five years including several high impact ones and reviewing articles for even more journals across my fields of interest, we value our published work in JCDR for their high standards in publishing scientific articles. The ease of submission, the rapid reviews in under a month, the high quality of their reviewers and keen attention to the final process of proofs and publication, ensure that there are no mistakes in the final article. We have been asked clarifications on several occasions and have been happy to provide them and it exemplifies the commitment to quality of the team at JCDR."



Prof. Somashekhar Nimbalkar
Head, Department of Pediatrics, Pramukhswami Medical College, Karamsad
Chairman, Research Group, Charutar Arogya Mandal, Karamsad
National Joint Coordinator - Advanced IAP NNF NRP Program
Ex-Member, Governing Body, National Neonatology Forum, New Delhi
Ex-President - National Neonatology Forum Gujarat State Chapter
Department of Pediatrics, Pramukhswami Medical College, Karamsad, Anand, Gujarat.
On Sep 2018




Dr. Kalyani R

"Journal of Clinical and Diagnostic Research is at present a well-known Indian originated scientific journal which started with a humble beginning. I have been associated with this journal since many years. I appreciate the Editor, Dr. Hemant Jain, for his constant effort in bringing up this journal to the present status right from the scratch. The journal is multidisciplinary. It encourages in publishing the scientific articles from postgraduates and also the beginners who start their career. At the same time the journal also caters for the high quality articles from specialty and super-specialty researchers. Hence it provides a platform for the scientist and researchers to publish. The other aspect of it is, the readers get the information regarding the most recent developments in science which can be used for teaching, research, treating patients and to some extent take preventive measures against certain diseases. The journal is contributing immensely to the society at national and international level."



Dr Kalyani R
Professor and Head
Department of Pathology
Sri Devaraj Urs Medical College
Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka
On Sep 2018




Dr. Saumya Navit

"As a peer-reviewed journal, the Journal of Clinical and Diagnostic Research provides an opportunity to researchers, scientists and budding professionals to explore the developments in the field of medicine and dentistry and their varied specialities, thus extending our view on biological diversities of living species in relation to medicine.
‘Knowledge is treasure of a wise man.’ The free access of this journal provides an immense scope of learning for the both the old and the young in field of medicine and dentistry as well. The multidisciplinary nature of the journal makes it a better platform to absorb all that is being researched and developed. The publication process is systematic and professional. Online submission, publication and peer reviewing makes it a user-friendly journal.
As an experienced dentist and an academician, I proudly recommend this journal to the dental fraternity as a good quality open access platform for rapid communication of their cutting-edge research progress and discovery.
I wish JCDR a great success and I hope that journal will soar higher with the passing time."



Dr Saumya Navit
Professor and Head
Department of Pediatric Dentistry
Saraswati Dental College
Lucknow
On Sep 2018




Dr. Arunava Biswas

"My sincere attachment with JCDR as an author as well as reviewer is a learning experience . Their systematic approach in publication of article in various categories is really praiseworthy.
Their prompt and timely response to review's query and the manner in which they have set the reviewing process helps in extracting the best possible scientific writings for publication.
It's a honour and pride to be a part of the JCDR team. My very best wishes to JCDR and hope it will sparkle up above the sky as a high indexed journal in near future."



Dr. Arunava Biswas
MD, DM (Clinical Pharmacology)
Assistant Professor
Department of Pharmacology
Calcutta National Medical College & Hospital , Kolkata




Dr. C.S. Ramesh Babu
" Journal of Clinical and Diagnostic Research (JCDR) is a multi-specialty medical and dental journal publishing high quality research articles in almost all branches of medicine. The quality of printing of figures and tables is excellent and comparable to any International journal. An added advantage is nominal publication charges and monthly issue of the journal and more chances of an article being accepted for publication. Moreover being a multi-specialty journal an article concerning a particular specialty has a wider reach of readers of other related specialties also. As an author and reviewer for several years I find this Journal most suitable and highly recommend this Journal."
Best regards,
C.S. Ramesh Babu,
Associate Professor of Anatomy,
Muzaffarnagar Medical College,
Muzaffarnagar.
On Aug 2018




Dr. Arundhathi. S
"Journal of Clinical and Diagnostic Research (JCDR) is a reputed peer reviewed journal and is constantly involved in publishing high quality research articles related to medicine. Its been a great pleasure to be associated with this esteemed journal as a reviewer and as an author for a couple of years. The editorial board consists of many dedicated and reputed experts as its members and they are doing an appreciable work in guiding budding researchers. JCDR is doing a commendable job in scientific research by promoting excellent quality research & review articles and case reports & series. The reviewers provide appropriate suggestions that improve the quality of articles. I strongly recommend my fraternity to encourage JCDR by contributing their valuable research work in this widely accepted, user friendly journal. I hope my collaboration with JCDR will continue for a long time".



Dr. Arundhathi. S
MBBS, MD (Pathology),
Sanjay Gandhi institute of trauma and orthopedics,
Bengaluru.
On Aug 2018




Dr. Mamta Gupta,
"It gives me great pleasure to be associated with JCDR, since last 2-3 years. Since then I have authored, co-authored and reviewed about 25 articles in JCDR. I thank JCDR for giving me an opportunity to improve my own skills as an author and a reviewer.
It 's a multispecialty journal, publishing high quality articles. It gives a platform to the authors to publish their research work which can be available for everyone across the globe to read. The best thing about JCDR is that the full articles of all medical specialties are available as pdf/html for reading free of cost or without institutional subscription, which is not there for other journals. For those who have problem in writing manuscript or do statistical work, JCDR comes for their rescue.
The journal has a monthly publication and the articles are published quite fast. In time compared to other journals. The on-line first publication is also a great advantage and facility to review one's own articles before going to print. The response to any query and permission if required, is quite fast; this is quite commendable. I have a very good experience about seeking quick permission for quoting a photograph (Fig.) from a JCDR article for my chapter authored in an E book. I never thought it would be so easy. No hassles.
Reviewing articles is no less a pain staking process and requires in depth perception, knowledge about the topic for review. It requires time and concentration, yet I enjoy doing it. The JCDR website especially for the reviewers is quite user friendly. My suggestions for improving the journal is, more strict review process, so that only high quality articles are published. I find a a good number of articles in Obst. Gynae, hence, a new journal for this specialty titled JCDR-OG can be started. May be a bimonthly or quarterly publication to begin with. Only selected articles should find a place in it.
An yearly reward for the best article authored can also incentivize the authors. Though the process of finding the best article will be not be very easy. I do not know how reviewing process can be improved. If an article is being reviewed by two reviewers, then opinion of one can be communicated to the other or the final opinion of the editor can be communicated to the reviewer if requested for. This will help one’s reviewing skills.
My best wishes to Dr. Hemant Jain and all the editorial staff of JCDR for their untiring efforts to bring out this journal. I strongly recommend medical fraternity to publish their valuable research work in this esteemed journal, JCDR".



Dr. Mamta Gupta
Consultant
(Ex HOD Obs &Gynae, Hindu Rao Hospital and associated NDMC Medical College, Delhi)
Aug 2018




Dr. Rajendra Kumar Ghritlaharey

"I wish to thank Dr. Hemant Jain, Editor-in-Chief Journal of Clinical and Diagnostic Research (JCDR), for asking me to write up few words.
Writing is the representation of language in a textual medium i e; into the words and sentences on paper. Quality medical manuscript writing in particular, demands not only a high-quality research, but also requires accurate and concise communication of findings and conclusions, with adherence to particular journal guidelines. In medical field whether working in teaching, private, or in corporate institution, everyone wants to excel in his / her own field and get recognised by making manuscripts publication.


Authors are the souls of any journal, and deserve much respect. To publish a journal manuscripts are needed from authors. Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards. Both ways its true "No authors-No manuscripts-No journals" and "No journals–No manuscripts–No authors". Reviewing a manuscript is also a very responsible and important task of any peer-reviewed journal and to be taken seriously. It needs knowledge on the subject, sincerity, honesty and determination. Although the process of reviewing a manuscript is a time consuming task butit is expected to give one's best remarks within the time frame of the journal.
Salient features of the JCDR: It is a biomedical, multidisciplinary (including all medical and dental specialities), e-journal, with wide scope and extensive author support. At the same time, a free text of manuscript is available in HTML and PDF format. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb 2007 of its first issue, it contained 5 articles only, and now in its recent volume published in April 2011, it contained 67 manuscripts. This e-journal is fulfilling the commitments and objectives sincerely, (as stated by Editor-in-chief in his preface to first edition) i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help. JCDR provides authors help in this regards.
Timely publication of journal: Publication of manuscripts and bringing out the issue in time is one of the positive aspects of JCDR and is possible with strong support team in terms of peer reviewers, proof reading, language check, computer operators, etc. This is one of the great reasons for authors to submit their work with JCDR. Another best part of JCDR is "Online first Publications" facilities available for the authors. This facility not only provides the prompt publications of the manuscripts but at the same time also early availability of the manuscripts for the readers.
Indexation and online availability: Indexation transforms the journal in some sense from its local ownership to the worldwide professional community and to the public.JCDR is indexed with Embase & EMbiology, Google Scholar, Index Copernicus, Chemical Abstracts Service, Journal seek Database, Indian Science Abstracts, to name few of them. Manuscriptspublished in JCDR are available on major search engines ie; google, yahoo, msn.
In the era of fast growing newer technologies, and in computer and internet friendly environment the manuscripts preparation, submission, review, revision, etc and all can be done and checked with a click from all corer of the world, at any time. Of course there is always a scope for improvement in every field and none is perfect. To progress, one needs to identify the areas of one's weakness and to strengthen them.
It is well said that "happy beginning is half done" and it fits perfectly with JCDR. It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb 2007. This had been made possible due to the efforts and the hard work put in it. The way the JCDR is improving with every new volume, with good quality original manuscripts, makes it a quality journal for readers. I must thank and congratulate Dr Hemant Jain, Editor-in-Chief JCDR and his team for their sincere efforts, dedication, and determination for making JCDR a fast growing journal.
Every one of us: authors, reviewers, editors, and publisher are responsible for enhancing the stature of the journal. I wish for a great success for JCDR."



Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
E-mail: drrajendrak1@rediffmail.com
On May 11,2011




Dr. Shankar P.R.

"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
Most of the manuscripts are published within 3 to 4 months of their submission if they are found to be suitable after the review process. JCDR is published bimonthly and the accepted articles were usually published in the next issue. Recently, due to the increased volume of the submissions, the review process has become slower and it ?? Section can take from 4 to 6 months for the articles to be reviewed. The journal has an extensive author support system and it has recently introduced a paid expedited review process. The journal also mentions the average time for processing the manuscript under different submission systems - regular submission and expedited review.
Strengths of the journal: The journal has an online first facility in which the accepted manuscripts may be published on the website before being included in a regular issue of the journal. This cuts down the time between their acceptance and the publication. The journal is indexed in many databases, though not in PubMed. The editorial board should now take steps to index the journal in PubMed. The journal has a system of notifying readers through e-mail when a new issue is released. Also, the articles are available in both the HTML and the PDF formats. I especially like the new and colorful page format of the journal. Also, the access statistics of the articles are available. The prepublication and the manuscript tracking system are also helpful for the authors.
Areas for improvement: In certain cases, I felt that the peer review process of the manuscripts was not up to international standards and that it should be strengthened. Also, the number of manuscripts in an issue is high and it may be difficult for readers to go through all of them. The journal can consider tightening of the peer review process and increasing the quality standards for the acceptance of the manuscripts. I faced occasional problems with the online manuscript submission (Pre-publishing) system, which have to be addressed.
Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work."



Dr. P. Ravi Shankar
KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
E-mail: ravi.dr.shankar@gmail.com
On April 2011
Anuradha

Dear team JCDR, I would like to thank you for the very professional and polite service provided by everyone at JCDR. While i have been in the field of writing and editing for sometime, this has been my first attempt in publishing a scientific paper.Thank you for hand-holding me through the process.


Dr. Anuradha
E-mail: anuradha2nittur@gmail.com
On Jan 2020

Important Notice

Research Protocol
Year : 2024 | Month : November | Volume : 18 | Issue : 11 | Page : ZK08 - ZK10 Full Version

Effect of Full Mouth Oral Rehabilitation on Bite Force and Body Mass Index in Patients with Early Childhood Caries: A Study Protocol


Published: November 1, 2024 | DOI: https://doi.org/10.7860/JCDR/2024/72955.20354
Rutuja Pralhad Patil, Monika Khubchandani, Harikishan Kanani

1. Postgraduate Student, Department of Paediatric and Preventive Dentistry, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India. 2. Assistant Professor, Department of Paediatric and Preventive Dentistry, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India. 3. Postgraduate Student, Department of Paediatric and Preventive Dentistry, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India.

Correspondence Address :
Dr. Rutuja Pralhad Patil,
Postgraduate Student, Department of Paediatric and Preventive Dentistry, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha-442107, Maharashtra, India.
E-mail: rutupatil4498@gmail.com

Abstract

Introduction: Early Childhood Caries (ECC) is a common condition affecting children, including chewing, aesthetics, the development of permanent teeth and phonetics. Full-mouth rehabilitation is crucial for addressing both immediate dental consequences and long-term oral health. Rehabilitating bite force can help detect stomatognathic system diseases and in understanding mandibular movements. Untreated dental caries can lead to malnutrition, linear growth failure and a negative Body Mass Index (BMI).

Need of the Study: Bite force assessment in the context of full-mouth rehabilitation of ECC will help measure functionality, monitor stability, finding issues early, ensuring treatment effectiveness and recommend any necessary adjustments for the child’s best dental health, to improve post-treatment quality of life.

Aim: The study aims to evaluate the effects of comprehensive oral rehabilitation on ECC patients by measuring bite forces and assessing changes in BMI in a paediatric population with primary dentition.

Materials and Methods: An experimental study will be conducted in the Department of Paediatric and Preventive Dentistry at Sharad Pawar Dental College and Hospital, Maharashtra, India, from August 2024 to December 2025. The Maximum Bite Force (MBF) in young children aged 4-5 years will be recorded at the central incisors and the right and left molar regions using a Portable Bite Force Measurement Device (BYTE). Anthropometric measurements of height and weight will be taken using scales, a portable stadiometer and a calibrated electronic device. The child’s BMI will be derived through weight and height calculations using an established equation. Participants will undergo bite force measurements and BMI evaluations both pre- and post-full mouth rehabilitation (which includes patient education along with preventive treatments like fluoride application and restorative procedures such as fillings, crowns and extractions). Anthropometric measurements will be taken post-treatment and results will be compared before and after the treatment. Statistical analysis will be done using the paired t-test and Pearson’s correlation test. Results will be considered statistically significant when the p-value is <0.05.

Keywords

Anthropometric measurements, Bite force measurement device, Dental caries, Full mouth rehabilitation

The ECC is a highly prevalent condition in children. Sometimes, even with all the oral health measures taken, there are concerns about maintaining the oral health of children with ECC (1).

The development of phonetics, the mastication system, aesthetics and preserving enough room for permanent teeth in the growing dentition are all influenced by primary teeth (2),(3). Severe Early Childhood Caries (S ECC) in children aged 3 to 5 is characterised as one or more deciduous maxillary anterior teeth that are cavitated, missing (from caries), or have smooth surface caries, or by DMFS scores of ≥4 (age 3), ≥5 (age 4), or ≥6 (age 5) (4). Children who lose their anterior teeth at a young age may have psychological effects, altered oral habits, diminished vertical dimension, an unpleasant facial expression and mispronunciation of labiodental sounds like “f” and “v (5).” As a result, this may hinder the development of a child’s personality and conduct. To restore all functions, including the child’s appearance, dental rehabilitation and prosthetic therapy are crucial (6). To address the acute dental problems associated with ECC, full mouth rehabilitation is vital for maintaining optimal dental function and alignment in the long-term. A comprehensive strategy to treat and prevent ECC in young children may include rehabilitation of biting force. The distribution of these balanced forces, such as the MBF or Maximum Voluntary Bite Force (MVBF), may be measured to create an index that can be used to determine how normal or deviant dental health is. The evaluation of occlusion and the stresses experienced by the stomatognathic system when in occlusion can help quantify a patient’s clinical difficulties in any impaired dentition (7). The bite force is an important factor in evaluating masticatory system performance. Bakke (2006) defines masticatory force as “the pressure exerted on the occlusal surfaces of teeth by the masticatory muscles.” Deviations in craniofacial biomechanics can lead to alterations in the jaw elevator muscles (8). Maximum Occlusal Bite Forces (MOBFs) vary depending on the developmental stage of dentition; during the early primary stage, it is 176 N, in the late primary stage, it is 240 N, whereas during the early mixed dentition, it increases to 289 N, in the late mixed dentition stage, it is 433 N and it reaches its highest value in the permanent dentition, which is 527 N (9). Various factors have been identified as influencing the intensity of biting strength, including age, gender, temporomandibular joint function, arch form, pain, dental occlusion, density and function of the masticatory muscles, the degree of dental caries, the existence of clinical signs (such as discomfort and abscesses in the teeth), the count of teeth in occlusal alignment, stages of dental eruption and the condition of dentition (10),(11).

Untreated dental caries may impact the development and growth of young children. Inadequate dietary intake combined with recurrent infections can lead to malnourishment, stunted growth and changes in BMI in children (12). Full mouth rehabilitation can positively impact a child’s BMI by improving their ability to chew and process food, leading to better nutrition and overall growth. This study aims to evaluate the effects of comprehensive oral rehabilitation on patients with ECC by measuring bite forces and assessing changes in BMI in a paediatric population with primary dentition.

Primary objective: To evaluate the Maximum Comfortable Voluntary Bite Force (MCVBF) at baseline, immediately after treatment completion and at 1-month follow-up.

Secondary objectives: To compare BMI at baseline and at the 1-month follow-up and to correlate bite force and BMI.

Null hypothesis: There will be no significant correlation between the bite force and BMI after full mouth rehabilitation in ECC patients.

Alternate hypothesis: There will be a significant correlation between bite force and BMI after full mouth rehabilitation in ECC patients.

Review Of Literature

Many conditions, such as various joint and muscle problems, occlusion disorders, dentures, age, gender, orthognathic surgery, psychological issues and trauma, may affect the function of the stomatognathic system. The force exerted by the masticatory muscles during tooth occlusion is known as the bite force. Understanding individual bite forces in different dentitions helps dentists evaluate the therapeutic effects of restorative rehabilitation and comprehend the mechanics of mastication (9).

In a study conducted by Singh R et al., 30 children with deciduous and mixed dentition were subjected to an in-vivo examination to measure maximal voluntary biting strength before and after dental intervention. The study revealed a mean biting intensity of 167.83 N, with males exhibiting 175.39 N and females 166.29 N. Following treatment, the mean biting force increased to 182.60 N. The study concluded that dental cavities and clinical signs have an adverse effect on maximal biting force (12).

Raghu R et al., conducted a study to evaluate the change in oral health-related quality of life in children under five undergoing complete oral rehabilitation under general anaesthesia. The study involved 50 healthy children affected by ECC. Quality of life was assessed using the Early Childhood Oral Health Impact Scale (ECOHIS) questionnaire, with significant reductions observed in all domains and total ECOHIS scores between baseline and one month and baseline and three months post-treatment. The study concluded that oral health-related quality of life significantly improved after complete oral rehabilitation under general anaesthesia and this improvement was sustained beyond the immediate post-treatment period (13).

Nandini K et al., studied 288 children aged 4 to 6 to determine maximal molar biting force. The research revealed that boys exhibited higher overall occlusal bite force than girls and non-carious teeth demonstrated higher masticatory bite force. Additionally, the flush terminal plane molar relationship exhibited the greatest occlusal force (14).

Mountain G et al., investigated biting forces in deciduous dentition and the impact of caries and malocclusion on maximal bite force in 251 children aged three to six. The study identified significant intra- and inter-individual variance in bite forces (15).

Amirabadi F et al., explored the effect of ECC treatment on the BMI of children aged 3-6 years (16). The study, involving 96 children divided into three groups, revealed significant changes in mean BMI within six months. Group I, which received comprehensive dental treatment under general anaesthesia at baseline, exhibited significantly greater BMI changes than the other two groups. The study concluded that although a significant negative relationship was found between ECC and BMI, oral hygiene and nutritional behaviour were the main confounding variables (16). The findings suggest that the treatment of ECC had a significant positive effect on BMI, highlighting the importance of healthcare professionals in identifying and treating at-risk children.

Material and Methods

An experimental study will be conducted in the Department of Paediatric and Preventive Dentistry at Sharad Pawar Dental College and Hospital, Maharashtra, India, from August 2024 to December 2025. The Institutional Ethics Committee has granted ethical approval for the research project (REF. NO. DMIHER(DU)/IEC/2024/235). The procedure will be explained to the parents and kids who are participating in the study. In addition, written informed parental consent will be obtained.

Inclusion criteria:

• Children aged 4 to 5 years.
• Children with primary dentition.
• Children with a Frankel behaviour rating score of positive (+) or definitely positive (++).
• Children with atleast two opposing carious primary molars.
• Children in good psychological and physical health.

Exclusion criteria:

• Children requiring specialised healthcare.
• Children with developmental dental anomalies.
• Children with temporomandibular joint disorders.
• Children with malocclusions.
• Children with parafunctional habits.
• Children with traumatic injuries.

Sample size calculation: Calculation using the T statistic and non centrality parameter:

A value of N=48.3030 gives the following calculations:
NCP=Non Centrality Parameter=vN * E/S?=2.8601 (12):
DF=Degrees of freedom=N-1=47.3030.
tα=Inverse of the two-tailed T distribution given probability of 1-(α/2) and DF of 47.3030=2.0114.
Beta (tα, DF, NCP)=0.199998. If N was calculated correctly, this should closely approximate the selected value of β1 above.
The ‘N’ calculated is rounded up to the next highest integer to give the group size.
N Group size ‘N’: 49

Study Procedure

Evaluating occlusal bite force: All bite force measurements will be recorded with the help of the Portable Bite Force Measurement Device (BYTE). It analyses force using a 12-bit ADC resolution with a mean range of 0 to 4096. Force measurements will be recorded in Newtons, weight (in kg) and pressure (in kPa) as SI units (17). Medical standards, Electrostatic Sensitive Instrumentation (ESI)/Electromagnetic Interference (EMI)-certified and safety standards will be used to evaluate the occlusal bite force before and after full-mouth rehabilitation of ECC patients. Full-mouth rehabilitation interventions in ECC patients will include restorative procedures such as fillings, crowns and extractions, with preventive treatments like fluoride application and oral hygiene education. These interventions will be administered comprehensively within two weeks to ensure uniformity and allow for consistent follow-up measurements.

To evaluate the bite force, the child should sit straight, facing ahead, with their head in a natural, unsupported posture and their back comfortably supported. The Frankfurt plane should be aligned with the ground and their feet should rest flat on the ground. Before recording, the child will be trained to perform their highest possible bite force without moving their head for 3 to 4 seconds. A 60-second break between multiple recordings will be given to avoid fatigue of the masticatory muscles. The greatest value will be selected as the peak bite force. Bite forces will be measured at the central incisors and the right and left molar regions (14). Next, the biting circular part with an acrylic stent will be placed exactly between the affected segment or group of teeth or the quadrant teeth and a single-use plastic bag cover will be placed at the biting end of the head. The program will instantly display changes on the reading Organic Light-emitting Diode (OLED) screen as soon as the youngster begins to bite. The measurements will go back to zero after the patient stops biting (18).

Anthropometric measurements: A weight and height scale will be used to collect anthropometric data, such as weight and height measurements. The child’s height will be measured to the closest 1.0 mm using a portable stadiometer. The child will stand against the measuring scale with their head in the Frankfurt plane, maintaining an upright posture and their feet correctly positioned about the foot posture corrector. A calibrated electronic portable instrument will be used to determine the child’s weight. BMI will be computed using a standard formula that considers height and weight (19).

Body Mass Index (BMI)= Weight (kg)/{Height (m)}2

The BMI-for-age percentile growth charts will be used according to the Centres for Disease Control and Prevention, as shown in (Table/Fig 1) (20). Every participant will have their BMI and biting force measured three times. The first measurement will be taken right before dental treatment begins. The same bite force measurements will be taken after the necessary dental treatment is completed and repeated four weeks±seven days later. Height and weight assessments will also be taken using the same format used for the pretreatment measurements.

Primary outcome: The primary outcome of this study is to evaluate the change in bite force in ECC patients after undergoing full-mouth oral rehabilitation. This will be measured using a bite force transducer or a similar device before and after the rehabilitation procedure to assess improvements in masticatory efficiency and functional bite strength.

Secondary outcome: BMI measurements will be taken before and after the rehabilitation to determine if improved oral health and function contribute to better nutritional intake and overall growth in young children.

Statistical Analysis

The results of the outcome variables will be tabulated and described using descriptive statistics and analysed using the Statistical Package for Social Sciences, Version 19.0 (SPSS) for Windows (SPSS Inc., Chicago, IL). A paired t-test will be used to compare the differences between the bite force values. Pearson’s correlation test will be used to correlate bite force and BMI. The results will be considered statistically significant when the p-value is <0.05.

References

1.
Meyer F, Enax J. Early childhood caries: Epidemiology, aetiology, and prevention. Int J Dent. 2018;2018:1415873. [crossref][PubMed]
2.
Thribhuvanan L. Full mouth rehabilitation of a 4-year-old child with severe early childhood caries: A case report. J Paediatr Dent. 2021;7(3):00-00. [crossref]
3.
Vittoba Setty J. Knowledge and awareness of primary teeth and their importance among parents in Bengaluru City, India. Int J Clin Paediatr Dent. 2016;9(1):56-61. [crossref][PubMed]
4.
Anil S, Anand PS. Early childhood caries: Prevalence, risk factors, and prevention. Front Paediatr. 2017;5:157. [crossref][PubMed]
5.
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DOI and Others

DOI: 10.7860/JCDR/2024/72955.20354

Date of Submission: May 17, 2024
Date of Peer Review: Jul 05, 2024
Date of Acceptance: Oct 01, 2024
Date of Publishing: Nov 01, 2024

AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. NA

PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: May 18, 2024
• Manual Googling: Jul 12, 2024
• iThenticate Software: Sep 24, 2024 (13%)

ETYMOLOGY: Author Origin

EMENDATIONS: 6

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