Scrub Typhus Induced Thrombotic Thrombocytopenia: A Rare Case Report
Correspondence Address :
Dr. Maharshi Patel,
Resident, Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha-442005, Maharashtra, India.
E-mail: maharship083@gmail.com
Scrub typhus is a zoonotic disease caused by Orientia tsutsugamushi. The bacterial infection is spread via Trombiculidae mites. A 50-year-old male patient was admitted with a complaint of fever, cough, breathlessness, and irrelevant talk for five days. The patient was chronic alcoholic and hypertensive for one year. After investigation patient was positive for scrub typhus. The patient had hepatitis, renal failure, thrombocytopenia, and right lower lobe pneumonia. The cause of thrombocytopenia in scrub typhus individuals could be the development of Thrombotic Thrombocytopenic Purpura (TTP), Disseminated Intravascular Coagulation (DIC), and thrombotic microangiopathy. In scrub typhus patients, TTP and Multiple Organ Dysfunction Syndrome (MODS) can be avoided with early diagnosis and effective treatment. Further research is warranted in such conditions to understand the molecular mechanism as well as to prevent mortality.
Bacteria, Hepatitis, Mites, Pneumonia, Renal failure
DOI: 10.7860/JCDR/2025/64201.20492
Date of Submission: Mar 21, 2023
Date of Peer Review: Apr 29, 2023
Date of Acceptance: May 23, 2023
Date of Publishing: Jan 01, 2025
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Mar 23, 2023
• Manual Googling: May 18, 2023
• iThenticate Software: May 20, 2023 (3%)
ETYMOLOGY: Author Origin
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